Collagen, Type VII, alpha 1 (COL7A1) ELISA Kits

COL7A1 encodes the alpha chain of type VII collagen. Additionally we are shipping COL7A1 Antibodies (15) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
COL7A1 1294 Q02388
COL7A1 12836 Q63870
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Top COL7A1 ELISA Kits at antibodies-online.com

Showing 3 out of 9 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.078 ng/mL 0.312-20 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Mouse 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Human 0.045 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 2 to 3 Days
$658.90
Details

More ELISA Kits for COL7A1 Interaction Partners

Cow (Bovine) Collagen, Type VII, alpha 1 (COL7A1) interaction partners

  1. Study provides evidence that a nonsense mutation in the COL7A1 gene causes recessive epidermolysis bullosa in Vorderwald and Rotes Hohenvieh cattle.

  2. The identified mutation causes a premature stop codon which leads to a truncated protein representing a complete loss of COL7A1 function (p.R1586*). We thus have identified a candidate causative

Human Collagen, Type VII, alpha 1 (COL7A1) interaction partners

  1. COL7A1 harbored mutations in the overwhelming majority of patients with dystrophic epidermolysis bullosa, and most of them in this Iranian cohort were consistent with autosomal recessive inheritance. Ninety percent of these mutations were homozygous recessive, reflecting consanguinity in these families.

  2. miR (show MLXIP ELISA Kits)-29 Regulates COL7A1 in Recessive Dystrophic Epidermolysis Bullosa, directly through targeting its 3' untranslated region at two distinct seed regions and indirectly through targeting an essential transcription factor required for basal COL7A1 expression, SP1 (show PSG1 ELISA Kits).

  3. A total of 50% of the pro-alpha1 (VII (show TH ELISA Kits)) procollagen chains will contain the dominant COL7A1 mutation if a DDEB patient carries one mutant COL7A1 in 100% of skin cells, which will lead to dystrophic epidermolysis bullosa

  4. The results in these two brothers show that COL7A1 mutation leads to persistent blistering in adulthood indicating that DEB (show SNRPF ELISA Kits) may persist throughout life in a mild form.

  5. This study is conducive to highlighting the phenotypic diversity of EBP (show EBP ELISA Kits), expanding the database on COL7A1 mutations in EBP (show EBP ELISA Kits) and laying the foundation for this family's prenatal genetic counselling.

  6. TANGO1 (show MIA3 ELISA Kits) is thus pivotal in concentrating procollagen VII (show TH ELISA Kits) in the lumen and recruiting ERGIC membranes on the cytoplasmic surface of the endoplasmic reticulum.

  7. Novel dystrophic epidermolysis bullosa COL7a1 framshift mutation c.5493delG (p.K1831Nfs*10) in exon 64 leads to a premature termination codon located 10 amino acids downstream in exon 64 (p.K1831Nfs*10) and is expected to result in a loss of function.

  8. In conclusion, we identified a Japanese founder recurrent mutation of c.6216 + 5G > T, inducing aberrant splicing of COL7A1 and tending to cause a mild phenotype of recessive dystrophic epidermolysis bullosa

  9. COL7A1 mutations have a role in Recessive Dystrophic Epidermolysis Bullosa and can be corrected meganuclease-mediated homology-directed repair

  10. Type VII (show TH ELISA Kits) collagen suppresses TGFbeta (show TGFB1 ELISA Kits) signaling and angiogenesis in cutaneous SCC (show CYP11A1 ELISA Kits) (squamous cell carcinoma). Patients with recessive dystrophic epidermolysis bullosa (RDEB) SCC (show CYP11A1 ELISA Kits) may benefit from anti-angiogenic therapy.

Mouse (Murine) Collagen, Type VII, alpha 1 (COL7A1) interaction partners

  1. miR (show MLXIP ELISA Kits)-29 Regulates COL7A1 in Recessive Dystrophic Epidermolysis Bullosa, directly through targeting its 3' untranslated region at two distinct seed regions and indirectly through targeting an essential transcription factor required for basal COL7A1 expression, SP1 (show SP1 ELISA Kits)

  2. The cystine knot (show KCNK7 ELISA Kits) is N-terminal to the collagen triple helix in in collagen type VII (show TH ELISA Kits) and IX and therefore probably impedes unfolding of the collagen triple helix from the N terminus.

  3. COL7A1 is required for re-epithelialization through organization of laminin-332 at the dermal-epidermal junction during wound healing.

  4. Tissue-bound, but not circulating, complement-fixing COL7-specific autoantibodies are associated with T helper type (Th)1 (show TH1L ELISA Kits) cell type cytokine expression and response in mice seusceptible to epidermolysis bullosa acquisita.

  5. An interaction of mvWFA2 with its neighboring domain mFNIII-9 was characterized with NMR spectroscopy and SPR (show SPR ELISA Kits)

  6. transforming growth factor beta1 stimulation of Col7a1 transcription is dependent on a putative interaction between Smads and AP1 (show JUN ELISA Kits).

  7. single amino acid substitutions in procollagen VII (show TH ELISA Kits) alter its self-assembly

  8. All mice developed circulating IgG autoantibodies that recognized type VII (show TH ELISA Kits) collagen and bound to the lamina densa of the dermal-epidermal junction[type VII (show TH ELISA Kits) collagen]

  9. Results describe the generation of a collagen VII (show TH ELISA Kits) alpha 1 hypomorphic mouse that serves as an immunocompetent animal model for dystrophic epidermolysis bullosa.

COL7A1 Antigen Profile

Antigen Summary

This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen.

Gene names and symbols associated with COL7A1

  • collagen, type VII, alpha 1 (COL7A1) antibody
  • collagen, type VII, alpha 1 (col7a1) antibody
  • collagen, type VII, alpha 1 (Col7a1) antibody
  • AW209154 antibody
  • COL7A1 antibody
  • EBD1 antibody
  • EBDCT antibody
  • EBR1 antibody

Protein level used designations for COL7A1

collagen alpha-1(VII) chain , collagen, type VII, alpha 1 (epidermolysis bullosa, dystrophic, dominant and recessive) , collagen, type VII, alpha 1 , alpha 1 type VII collagen , collagen alpha-1(VII) chain-like , LC collagen , collagen VII, alpha-1 polypeptide , long-chain collagen , procollagen, type VII, alpha 1

GENE ID SPECIES
403467 Canis lupus familiaris
460347 Pan troglodytes
507133 Bos taurus
709354 Macaca mulatta
100454508 Pongo abelii
100489404 Xenopus (Silurana) tropicalis
100523209 Sus scrofa
1294 Homo sapiens
12836 Mus musculus
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