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Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 Proteins (CYP2C19)

CYP2C19 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2C19 Antibodies (32) and CYP2C19 Kits (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CYP2C19 1557 P33261
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Top CYP2C19 Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Yeast (Pichia pastoris) Human Un-conjugated   10 mg Log in to see 2 to 3 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

CYP2C19 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,

More Proteins for Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) Interaction Partners

Human Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) interaction partners

  1. Individuals with CYP2C19*17 may have increased risk of ischemic events following endovascular treatment, independent of clopidogrel responsiveness.

  2. This is the first report to show a relationship between the CYP2C19 polymorphism and valproic acid-induced weight gain in female patients with epilepsy.

  3. findings indicated that carrying a CYP2C19*2 allele with a functional CYP2C19*1 allele had no significant association with in-stent restenosis 1 year after percutaneous coronary intervention

  4. AUC of omeprazole was higher in females while its elimination also took longer compared with males. AUC of omeprazole was significantly higher in Homz PMs (show PRB1 Proteins) indicating that CYP2C19* displayed genetically deficient metabolism in its homozygous state.

  5. Among patients with minor ischemic stroke or transient ischemic attack, the use of clopidogrel plus aspirin compared with aspirin alone reduced the risk of a new stroke only in the subgroup of patients who were not carriers of the CYP2C19 loss-of-function alleles. These findings support a role of CYP2C19 genotype in the efficacy of this treatment.

  6. CYP2C19 gene polymorphisms associated with different responses to antiplatelet therapy in patients with coronary artery disease.

  7. In a retrospective study of 17 critically ill patients treated for invasive aspergillosis with voriconazole it was found that the metabolizing capacity of CYP2C19 depended on the genotype.

  8. CYP2C19 metabolizer status is not associated with the composite outcome of cardiovascular death, MI, or stroke in medically managed ACS patients treated with clopidogrel or prasugrel.

  9. CYP2C19 ultrarapid metabolizers were associated with reduced tolerance to a fixed titration schedule of open-label escitalopram in this autism spectrum disorder study sample.

  10. Results suggest that CYP2D6 (show CYP2D6 Proteins) and CYP2C19 genotyping alone probably do not improve the prediction of treatment resistance in schizophrenia

CYP2C19 Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

Gene names and symbols associated with CYP2C19

  • cytochrome P450, family 2, subfamily C, polypeptide 19 (CYP2C19)
  • CPCJ protein
  • CYP2C protein
  • P450C2C protein
  • P450IIC19 protein

Protein level used designations for CYP2C19

cytochrome P450 2C , (R)-limonene 6-monooxygenase , (S)-limonene 6-monooxygenase , (S)-limonene 7-monooxygenase , CYPIIC17 , CYPIIC19 , S-mephenytoin 4-hydroxylase , cytochrome P-450 II C , cytochrome P450 2C19 , cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19 , cytochrome P450-11A , cytochrome P450-254C , flavoprotein-linked monooxygenase , mephenytoin 4'-hydroxylase , mephenytoin 4-hydroxylase , microsomal monooxygenase , xenobiotic monooxygenase

510380 Bos taurus
1557 Homo sapiens
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