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Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 Proteins (CYP2C19)

CYP2C19 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2C19 Antibodies (32) and CYP2C19 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CYP2C19 1557 P33261
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Top CYP2C19 Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Yeast (Pichia pastoris) Human Un-conjugated   10 mg Log in to see 2 to 3 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

CYP2C19 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,

More Proteins for Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) Interaction Partners

Human Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) interaction partners

  1. Letter: no association between presence or severity of endoscopic lesions and the MDR1 C3435T, CYP2C19*2 and CYP2C19*3 gene polymorphisms in gastro-duodenal diseases.

  2. We conclude that CYP2C9 (show CYP2C9 Proteins)/2C19 genotype is not relevant for variability in valproic acid exposure.

  3. While CYP2C19 genetic polymorphisms significantly affected plasma pantoprazole concentrations, polymorphisms of CYP2C19, CYP3A4 (show CYP3A4 Proteins) and MDR1 did not affect H. pylori eradication rates.

  4. In contradiction to their clinical impact in first-generation DES (show DES Proteins) era, CYP2C19 loss-of-function alleles may not affect clinical outcome of clopidogrel therapy in patients treated with newer-generation drug-eluting stent

  5. The CYP2C19 gene plays a potential maker to evaluate nephropathy in cardio-cerebral vascular disease patients.

  6. Patients treated with voriconazole with CYP2C19 poor metabolizer phenotype were associated with increased treatment success rate with and trough concentrations as compared with those with extensive metabolizer phenotype

  7. Although the genotypes of CYP2C19 variants were not statistically significant, the results of this study suggest a possible effect of the poor metabolizer genotype on the efficacy of H. pylori eradication.

  8. Our study identified CYP2C19*3 and CES1 (show CES1 Proteins) rs8192950 as genetic polymorphisms related to recurrent ischemic events in patients with extracranial or intracranial occlusive disease, demonstrating the important roles of CYP2C19 and CES1 (show CES1 Proteins) in patients treated with clopidogrel

  9. CYP2C19*2/*3 polymorphisms may be associated with clopidogrel resistance. Wild-type homozygote and single mutant heterozygote of CYP2C19*2/*3 can be given a normal dose of clopidogrel, while carriers with single mutant homozygote or double mutant heterozygote require ticagrelor antiplatelet therapy as an alternative.

  10. We found that CYP2C19 polymorphism did not have any significant effect on the diazepam dose requirement, time duration needed for successful treatment or on the persistent symptoms after loading dose of diazepam in South Indian population in acute alcohol withdrawal treatment.

CYP2C19 Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

Gene names and symbols associated with CYP2C19

  • cytochrome P450, family 2, subfamily C, polypeptide 19 (CYP2C19)
  • CPCJ protein
  • CYP2C protein
  • P450C2C protein
  • P450IIC19 protein

Protein level used designations for CYP2C19

cytochrome P450 2C , (R)-limonene 6-monooxygenase , (S)-limonene 6-monooxygenase , (S)-limonene 7-monooxygenase , CYPIIC17 , CYPIIC19 , S-mephenytoin 4-hydroxylase , cytochrome P-450 II C , cytochrome P450 2C19 , cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19 , cytochrome P450-11A , cytochrome P450-254C , flavoprotein-linked monooxygenase , mephenytoin 4'-hydroxylase , mephenytoin 4-hydroxylase , microsomal monooxygenase , xenobiotic monooxygenase

510380 Bos taurus
1557 Homo sapiens
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