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Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 Proteins (CYP2C19)

CYP2C19 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2C19 Antibodies (32) and CYP2C19 Kits (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CYP2C19 1557 P33261
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Top CYP2C19 Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Yeast (Pichia pastoris) Human Un-conjugated   10 mg Log in to see 2 to 3 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

CYP2C19 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,

More Proteins for Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) Interaction Partners

Human Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) interaction partners

  1. Data suggest that primary cytochrome P450 in liver microsomes catalyzing 9-hydroxylation of (-)-cis (show CISH Proteins)- and (-)-trans-rose oxide is CYP2B6 (show CYP2B6 Proteins) (and CYP2C19 to some extent); rose oxide is aroma compound from essential oils and is used in food and perfume.

  2. The mean plasma concentrations and the mean dose-corrected (C/D) plasma levels of DCIT were significantly higher in patients with the CYP2C19*1/*1 genotype.

  3. a significant association was found between CYP2C19*2 and PLA1 (show POU2F3 Proteins)/A2 in clopidogrel semi-responders.

  4. This study demonstrated that Clinical evaluation of analgesic ineffectiveness and adverse effects led to the high likelihood of identifying patients with CYP2D6 (show CYP2D6 Proteins), CYP2C19, and CYP2C9 (show CYP2C9 Proteins) alleles associated with alterations in analgesic metabolism.

  5. Our results shed new light on CYP2C19 polymorphisms in Li individuals

  6. no evidence was found that CYP2C19 polymorphisms are associated with susceptibility to primary open-angle glaucoma.

  7. Individuals with CYP2C19*17 may have increased risk of ischemic events following endovascular treatment, independent of clopidogrel responsiveness.

  8. This is the first report to show a relationship between the CYP2C19 polymorphism and valproic acid-induced weight gain in female patients with epilepsy.

  9. findings indicated that carrying a CYP2C19*2 allele with a functional CYP2C19*1 allele had no significant association with in-stent restenosis 1 year after percutaneous coronary intervention

  10. AUC of omeprazole was higher in females while its elimination also took longer compared with males. AUC of omeprazole was significantly higher in Homz PMs (show PRB1 Proteins) indicating that CYP2C19* displayed genetically deficient metabolism in its homozygous state.

CYP2C19 Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

Gene names and symbols associated with CYP2C19

  • cytochrome P450, family 2, subfamily C, polypeptide 19 (CYP2C19)
  • CPCJ protein
  • CYP2C protein
  • P450C2C protein
  • P450IIC19 protein

Protein level used designations for CYP2C19

cytochrome P450 2C , (R)-limonene 6-monooxygenase , (S)-limonene 6-monooxygenase , (S)-limonene 7-monooxygenase , CYPIIC17 , CYPIIC19 , S-mephenytoin 4-hydroxylase , cytochrome P-450 II C , cytochrome P450 2C19 , cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19 , cytochrome P450-11A , cytochrome P450-254C , flavoprotein-linked monooxygenase , mephenytoin 4'-hydroxylase , mephenytoin 4-hydroxylase , microsomal monooxygenase , xenobiotic monooxygenase

510380 Bos taurus
1557 Homo sapiens
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