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CYP2D6 Proteins

(Cytochrome P450, Family 2, Subfamily D, Polypeptide 6 (CYP2D6))
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug\; sparteine and propafenone, both anti-arrythmic drugs\; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population\; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme's substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
CYP2D6 Protein (AA 91-190) (GST tag) CYP2D6 Protein (AA 91-190) (GST tag) CYP2D6 Protein (AA 91-190) (GST tag) (ABIN1350974)

CYP2D6 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

CYP2D6 Protein (His tag) (ABIN7407760)

CYP2D6 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC

CYP2D6 Protein (AA 236-472) (His tag) (ABIN7401203)

CYP2D6 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC

CYP2D6 Proteins by Origin

Find CYP2D6 Proteins for a variety of species such as anti-Human CYP2D6, anti-Rat CYP2D6, anti-Bonobo CYP2D6. The species listed below are among those available. Click on a link to go to the corresponding products.

CYP2D6 Proteins by Source

Here you will find CYP2D6 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CYP2D6 Proteins by Protein Type

Here you can find CYP2D6 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

CYP2D6 Proteins by Application

Find CYP2D6 Proteins validated for a specific application such as WB, ELISA, SDS, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

CYP2D6 Proteins by Biological Activity

Find CYP2D6 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular CYP2D6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350974
Quantity 10 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7407760
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7401203
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3078040
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2712768
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2712769
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6238518
Quantity 50 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN6378889
Quantity 1 mg
Datasheet Datasheet
Reactivity Bonobo
Source Yeast
Validations
Cat. No. ABIN1625688
Quantity 1 mg
Datasheet Datasheet
Reactivity Chimpanzee
Source Yeast
Validations
Cat. No. ABIN1625989
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source
Validations
Cat. No. ABIN1062431
Quantity 1 mg
Datasheet Datasheet

Aliases for CYP2D6 Proteins

cytochrome P450 family 2 subfamily D member 6 (CYP2D6) Proteins
cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6) Proteins
cytochrome 2D6 (CYP2D6) Proteins
cytochrome P450, family 2, subfamily D, polypeptide 6 (cyp2d6-b) Proteins
cytochrome P450 family 2 subfamily D member 6 S homeolog (cyp2d6.S) Proteins
cytochrome P450 family 2 subfamily D member 6 (cyp2d6) Proteins
cytochrome P450 2D6 (CYP2D6) Proteins
cytochrome P450 2D6-like (LOC100988273) Proteins
CPD6 Proteins
CYP2D Proteins
cyp2d2 Proteins
CYP2D6 Proteins
cyp2d6-a Proteins
CYP2D7AP Proteins
CYP2D7BP Proteins
CYP2D7P2 Proteins
CYP2D8P2 Proteins
CYP2D42 Proteins
CYP2DL1 Proteins
CYPIID6 Proteins
MGC64445 Proteins
P450-DB1 Proteins
P450C2D Proteins
P450DB1 Proteins
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