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Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 Proteins (CYP2C9)

CYP2C9 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2C9 Antibodies (59) and CYP2C9 Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CYP2C9 1559 P11712
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Top CYP2C9 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Yeast (Pichia pastoris) Human Un-conjugated   10 mg Log in to see 2 to 3 Days
$157.50
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CYP2C9 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,

More Proteins for Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9) Interaction Partners

Human Cytochrome P450, Family 2, Subfamily C, Polypeptide 9 (CYP2C9) interaction partners

  1. P450 (Cytochrome) Oxidoreductase (show POR Proteins) Gene (POR (show POR Proteins)) Common Variant (POR (show POR Proteins)*28) Significantly Alters CYP2C9 Activity in Swedish, But Not in Korean Healthy Subjects

  2. VKORC1S1639 GG and the wild type CYP2C9*1*1 genotypes are associated with the high-dose requirement for warfarin therapy.

  3. This study demonstrated that Clinical evaluation of analgesic ineffectiveness and adverse effects led to the high likelihood of identifying patients with CYP2D6 (show CYP2D6 Proteins), CYP2C19 (show CYP2C19 Proteins), and CYP2C9 alleles associated with alterations in analgesic metabolism.

  4. Patients with variant CYP2C9 are at increased risk for cyclophosphamide-induced leukopenia but may have a better chance to respond to treatment.

  5. The novel mutation can greatly decrease the enzymatic activity of the CYP2C9 enzyme both in vitro and in vivo

  6. Rate of fall in INR (show INSR Proteins) on warfarin withdrawal is dependent on CYP2C9 genotype.

  7. There was no association between CYP2C9*2 and*3 and acenocoumarol or warfarin requirements.

  8. We did not observe any association of CYP2C8 (show CYP2C8 Proteins)*2, CYP2C8 (show CYP2C8 Proteins)*3, CYP2C9*2 and CYP2C9*3 with myocardial infarction

  9. The CYP2C9*3 is a reasonable predictive genetic marker to anticipate SCARs (severe cutaneous adverse reactions) from phenytoin.

  10. Our algorithm achieved a determination coefficient of 40% including the variables age, gender, weight, height, self-declared race, amiodarone use, enzyme inducers use, VKORC1 (show VKORC1 Proteins) genotypes and predicted phenotypes according to CYP2C9 polymorphisms

CYP2C9 Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

Gene names and symbols associated with CYP2C9

  • cytochrome P450, family 2, subfamily C, polypeptide 9 (CYP2C9)
  • CPC9 protein
  • CYP2C protein
  • CYP2C10 protein
  • CYPIIC9 protein
  • P450IIC9 protein

Protein level used designations for CYP2C9

cytochrome P-450 S-mephenytoin 4-hydroxylase , cytochrome P-450MP , cytochrome P450 2C9 , cytochrome P450 PB-1 , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase

GENE ID SPECIES
1559 Homo sapiens
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