anti-D-Dopachrome Tautomerase (DDT) Antibodies

D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. Additionally we are shipping D-Dopachrome Tautomerase Kits (21) and D-Dopachrome Tautomerase Proteins (18) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DDT 29318 P80254
DDT 1652 P30046
DDT 13202 O35215
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Top anti-D-Dopachrome Tautomerase Antibodies at

Showing 10 out of 74 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC (p), WB Anti-DDT antibody, IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Log in to see 4 to 6 Days
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged DDT is approximately 3ng/ml as a capture antibody. Western Blot analysis of DDT expression in transfected 293T cell line by DDT monoclonal antibody (M01), clone 1G1.Lane 1: DDT transfected lysate(12.7 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 11 to 12 Days
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 7 to 9 Days
Human Mouse Un-conjugated IHC (p), WB 100 μL Log in to see 7 to 9 Days
Human Mouse Un-conjugated IF, IHC (p), WB 100 μL Log in to see 7 to 9 Days
Human Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IHC (p), IHC, WB Western Blot: DDT Antibody [NBP1-33461] - Sample (30 ug of whole cell lysate) A: Raji 15% SDS PAGE, antibody diluted at 1:500. Immunohistochemistry-Paraffin: DDT Antibody [NBP1-33461] - Paraffin-embedded NCIN87 xenograft, using antibody at 1:100 dilution. 100 μL Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded NCIN87 xenograft, using DDT, antibody at 1:100 dilution. WB Image Rat tissue extract (50 μg) was separated by 15% SDS-PAGE, and the membrane was blotted with DDT antibody [N1C3] , diluted at 1:500. 100 μL Log in to see 1 to 2 Days
Human Rabbit Un-conjugated ICC, IHC (p), ELISA, WB   100 μg Log in to see 4 to 6 Days

DDT Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus) , ,

Human , , , ,
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Mouse (Murine) , ,

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Top referenced anti-D-Dopachrome Tautomerase Antibodies

  1. Cow (Bovine) Polyclonal DDT Primary Antibody for WB - ABIN2782455 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)

  2. Human Monoclonal DDT Primary Antibody for ELISA, WB - ABIN560588 : Hiyoshi, Konishi, Uemura, Matsuzaki, Tsukamoto, Sugimoto, Takeda, Dakeshita, Kitayama, Takami, Sawachika, Kido, Arisawa: D-Dopachrome tautomerase is a candidate for key proteins to protect the rat liver damaged by carbon tetrachloride. in Toxicology 2008 (PubMed)

More Antibodies against D-Dopachrome Tautomerase Interaction Partners

Human D-Dopachrome Tautomerase (DDT) interaction partners

  1. Study demonstrated that DDT was over- expressed in pancreatic ductal adenocarcinoma (PDAC) tissues and cell lines in a pattern correlated with MIF (show AMH Antibodies), and knockdown of DDT and MIF (show AMH Antibodies) in PANC- 1 cells cooperatively inhibited cell proliferation, invasion and tumor formation. The tautomerase activities of both MIF (show AMH Antibodies) and DDT are required for their negative regulatory role in p53 (show TP53 Antibodies) and their tumor-promoting functions.

  2. DDT was increased in burn patients.

  3. Gene expression level of DDT is significantly higher in AD patients when compared to normal controls.

  4. High MIF-2 (show CENPC1 Antibodies) levels are predictive of the development of organ dysfunction in myocardial ischemia reperfusion injury.

  5. Both p53 (show TP53 Antibodies) wildtype and mutant human lung adenocarcinoma tumors rely on MIF (show AMH Antibodies) family members for maximal cell growth and survival.

  6. findings identify DDT as a functionally redundant but more potent cytokine to MIF (show AMH Antibodies) in cancer and suggest that current attempts to inhibit MIF (show AMH Antibodies) signaling may fail because of DDT compensation.

  7. D-dopachrome tautomerase secreted from adipocytes acts on preadipocytes to promote IL-6 (show IL6 Antibodies) expression and to inhibit adipogenesis by suppressing the induction of genes encoding adipogenic regulators

  8. DDT acts on adipocytes to regulate lipid metabolism through AMPK (show PRKAA1 Antibodies) and/or PKA pathway(s) and improves glucose intolerance caused by obesity.

  9. These data indicate that D-DT is a MIF (show AMH Antibodies)-like cytokine.

  10. D-DT-dependent beta-catenin (show CTNNB1 Antibodies) stabilization is regulated by COX-2 (show COX2 Antibodies) expression, suggesting the existence of an amplification loop between COX-2 (show COX2 Antibodies)- and beta-catenin (show CTNNB1 Antibodies)-mediated transcription in these cells

Mouse (Murine) D-Dopachrome Tautomerase (DDT) interaction partners

  1. cardiomyocyte secretion of DDT has important autocrine/paracrine effects during ischemia-reperfusion that protect the heart against injury

  2. These data point to a potential involvement of D-dopachrome tautomerase activity in the mature mouse brain, and suggest some functional and evolutionary relationship between innate immunity and tautomerization of D-dopachrome in mammalian species

  3. These data indicate that D-DT is a MIF (show MIF Antibodies)-like cytokine.

D-Dopachrome Tautomerase (DDT) Antigen Profile

Protein Summary

D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. The DDT gene is related to the migration inhibitory factor (MIF) in terms of sequence, enzyme activity, and gene structure. DDT and MIF are closely linked on chromosome 22.

Gene names and symbols associated with DDT

  • D-dopachrome tautomerase (ddt) antibody
  • D-dopachrome decarboxylase a (ddt-a) antibody
  • D-dopachrome decarboxylase b (ddt-b) antibody
  • D-dopachrome tautomerase (DDT) antibody
  • D-dopachrome tautomerase (Ddt) antibody
  • D-dopachrome tautomerase-like (LOC100337941) antibody
  • C78655 antibody
  • DDCT antibody
  • DDT antibody
  • ddt-a antibody
  • ddt-b antibody
  • wu:fb49f11 antibody
  • zgc:86714 antibody

Protein level used designations for DDT

D-dopachrome decarboxylase , D-dopachrome decarboxylase-A , D-dopachrome tautomerase-A , D-dopachrome decarboxylase-B , D-dopachrome tautomerase-B , D-dopachrome tautomerase , dopachrome isomerase , phenylpyruvate tautomerase II

415237 Danio rerio
447275 Xenopus laevis
494727 Xenopus laevis
550015 Xenopus (Silurana) tropicalis
699070 Macaca mulatta
699933 Macaca mulatta
747265 Pan troglodytes
747294 Pan troglodytes
100301489 Taeniopygia guttata
29318 Rattus norvegicus
1652 Homo sapiens
607589 Canis lupus familiaris
615999 Bos taurus
13202 Mus musculus
416937 Gallus gallus
100155535 Sus scrofa
100337941 Oryctolagus cuniculus
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