anti-Defensin, beta 1 (DEFB1) Antibodies

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Additionally we are shipping beta Defensin 1 Kits (47) and beta Defensin 1 Proteins (45) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DEFB1 13214 P56386
DEFB1 83687 O89117
DEFB1 1672 P60022
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Top anti-beta Defensin 1 Antibodies at antibodies-online.com

Showing 10 out of 161 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Anti-beta Defensin 1 antibody,Western blotting All lanes: Anti Defensin 1  at 0.5ug/ml WB : COLO320 Whole Cell Lysate at 40ug Predicted bind size: 7KD Observed bind size: 7KD Anti-beta Defensin 1 antibody, IHC(P) IHC(P): Lung Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Mouse Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$676.50
Details
Mouse Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-beta Defensin 1 Polyclonal Antibody, Unconjugated (ABIN738591) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded rat kidney labeled with Anti-beta Defensin 1 Polyclonal Antibody, Unconjugated (ABIN738591) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 2 to 6 Days
$327.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of Defensin beta 1 expression in HEK293T (A), mouse liver (B), rat heart (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Mouse Un-conjugated ELISA, WB   10 μg Log in to see 3 to 4 Days
$293.33
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Biotin EIA, WB 50 μg Log in to see 6 to 8 Days
$368.50
Details
Human Rabbit Biotin ELISA, WB 50 μg Log in to see 3 to 4 Days
$562.94
Details
Mouse Rabbit Cy5 IF (p)   100 μL Log in to see 14 to 21 Days
$405.90
Details

DEFB1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-beta Defensin 1 Antibodies

  1. Human Polyclonal beta Defensin 1 Primary Antibody for ELISA, WB - ABIN2473296 : Goldman, Anderson, Stolzenberg, Kari, Zasloff, Wilson: Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis. in Cell 1997 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal beta Defensin 1 Primary Antibody for IHC (p), ELISA - ABIN2473295 : Kelly, Glover, Campbell, Kominsky, Ehrentraut, Bowers, Bayless, Saeedi, Colgan: Fundamental role for HIF-1? in constitutive expression of human ? defensin-1. in Mucosal immunology 2013 (PubMed)
    Show all 2 Pubmed References

More Antibodies against beta Defensin 1 Interaction Partners

Cow (Bovine) Defensin, beta 1 (DEFB1) interaction partners

  1. Stimulation of umbilical-vein endothelial cells with S. aureus or LPS (show IRF6 Antibodies) induced the expression of bovine beta-defensin 1. This expression was regulated by the autocrine production of tumor necrosis factor-alpha (show TNF Antibodies).

  2. The synthetic peptides bovine enteric beta-defensin (EBD), bovine neutrophil beta-defensin (BNBD) 9 and BNBD 3 are chemotactic for immature dendritic cells.(

Mouse (Murine) Defensin, beta 1 (DEFB1) interaction partners

  1. Fenofibrate and gemfibrozil inhibit LPS (show TLR4 Antibodies)-induced inflammatory activation of macrophages via PPARalpha (show PPARA Antibodies)/beta-defensin 1/TLR4 (show TLR4 Antibodies) pathway.

  2. these studies demonstrate a role for the murine beta-defensin 1 peptide in early control of Candida infection in a murine model of mucosal candidiasis

  3. Akt1 (show AKT1 Antibodies) is involved in the regulation of defensin (show DEF Antibodies) expression and the innate immune response important for bacterial clearance

  4. Histopathology showed a greater inflammatory influx in the lungs of mBD-1((-/-)) mice at Day 3 postinfection compared with WT C57BL/6 mice

  5. The decreased production of antimicrobial peptides by burn-site epidermal keratinocytes influenced by Gr-1 (show GSR Antibodies)(+)CD11b (show ITGAM Antibodies)(+) cells was shown to be restored by glycyrrhizin.

  6. elimination of mBD-1 results in a defect in the ability of the host to clear H. influenzae from the lung, which is most consistent with this peptide functioning as an antibiotic at the airway surface.

  7. The expression of BD1 was significantly elevated in the lungs of cigarette smoke-exposed mice compared with air-exposed mice.

  8. Although both murine beta-defensin (mBD)-1 and mBD2 (show MBD2 Antibodies) are constitutively expressed in normal BALB/c and C57BL/6 corneas, mBD-1 is not required for host resistance against Pseudomonas aeruginosa-induced corneal infection.

Human Defensin, beta 1 (DEFB1) interaction partners

  1. It was concluded that bile acids can differentially regulate colonic epithelial beta-defensin expression and secretion; the authors discuss the implications for intestinal health and disease.-

  2. data provide important insight into the in vivo kinetics of HBD (show HBd Antibodies) expression, the mechanism of HBD1 induction by HIV-1, and the role of HBDs in the early innate response to HIV-1 during acute infection

  3. CpG methylation frequencies in the DEFB1 low CpG-content promoter were significantly higher in the prostate malignant tissues than in adjacent benign tissues.

  4. DEFB1 - genotypes were correlated with the hBD-1 salivary concentration.

  5. Coding missense and nonsense single nucleotide polymorphisms result in less active HBD1 antibacterial activity against Escherichia coli.

  6. A significant difference was found between the levels of staining of TLR-2 (show TLR2 Antibodies), TLR-4 (show TLR4 Antibodies) and hBD-1 in different lesions from the epidermis, inflammation region, dermis and skin appendages (p < 0.05) in patients with acne vulgaris.

  7. Expression of hBD-1, hBD-2 (show DEFB4 Antibodies), hBD-3 (show DEFB103A Antibodies), and hBD-4 (show DEFB104A Antibodies) in healthy and chronic periodontitis gingiva.

  8. The -44 CC genotype of the beta-defensin-1 gene (DEFB1 rs1800972) may be associated with susceptibility to chronic periodontitis in Japanese.

  9. No clear association was found between the DEFB1 polymorphisms and tuberculosis.

  10. DEFB1 polymorphisms alone may not influence pathology susceptibility, however they could possibly concur, together with other factors involved in the genetic control of innate immune system, in the predisposition towards recurrent tonsillitis

Pig (Porcine) Defensin, beta 1 (DEFB1) interaction partners

  1. pBD1 showed low hemolytic activity and high thermal stability. These properties are relevant for the biotechnological applications of the peptide.

  2. Zinc sulfate and L-isoleucine induce beta defensin expression in a porcine cell line.

  3. Presence of beta-defensin 1 in the upper respiratory tract is associated with resistance against respiratory infection with Bordetella pertussis in older piglets

beta Defensin 1 (DEFB1) Antigen Profile

Protein Summary

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.

Gene names and symbols associated with DEFB1

  • avian beta-defensin 3 (AvBD3) antibody
  • defensin beta 1 (DEFB1) antibody
  • beta defensin (LOC100296173) antibody
  • beta-defensin 1-like (LOC100861170) antibody
  • defensin beta 1 (Defb1) antibody
  • defensin, beta 1 (DEFB1) antibody
  • enteric beta-defensin (EBD) antibody
  • avian beta-defensin 1 (AvBD1) antibody
  • AW260221 antibody
  • BD-1 antibody
  • BD1 antibody
  • CBD1 antibody
  • DEFB-1 antibody
  • DEFB1 antibody
  • DEFB1-like antibody
  • DEFB101 antibody
  • EBD antibody
  • GAL3 antibody
  • HBD1 antibody
  • PBD-1 antibody
  • RHBD-1 antibody

Protein level used designations for DEFB1

Gal 3 , antimicrobial peptide-3 , beta-defensin 1 , beta-defensin 3 , beta-defensin prepropeptide , gal-3 , gallinacin-3 , Beta-defensin 1 , Defensin, beta 1 , BD-1 , rBD-1 , beta-defensin-1 , prepro-beta-defensin 1 , defensin, beta 1 (enteric) , enteric beta-defensin , enteric prepro-beta-defensin , beta defensin-1 homolog , cBD1 , Gal 1 , Gal 1-alpha , antimicrobial peptide 1 , antimicrobial peptide CHP2 , chicken heterophil peptide 2 , gal-1 alpha , gallinacin-1 alpha

GENE ID SPECIES
395363 Gallus gallus
611241 Canis lupus familiaris
100296173 Bos taurus
100861170 Capra hircus
13214 Mus musculus
83687 Rattus norvegicus
1672 Homo sapiens
396819 Sus scrofa
281743 Bos taurus
574187 Macaca mulatta
450100 Pan troglodytes
395841 Gallus gallus
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