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anti-Diaphanous Homolog 3 (Drosophila) (DIAPH3) Antibodies

DIAPH3 encodes a member of the diaphanous subfamily of the formin family. Additionally we are shipping DIAPH3 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DIAPH3 290396  
DIAPH3 56419 Q9Z207
DIAPH3 81624 Q9NSV4
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Top anti-DIAPH3 Antibodies at

Showing 10 out of 60 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of DIAPH3 Antibody 0.4 mL Log in to see 6 to 8 Days
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.89 KDa) . 50 μL Log in to see 9 Days
Human Goat Un-conjugated ELISA   0.1 mg Log in to see 5 to 7 Days
Human Rabbit Un-conjugated IHC (p) IHC-P Image DIAPH3 antibody [C1C3] detects DIAPH3 protein at cytoplasm on human placenta by immunohistochemical analysis. Sample: Paraffin-embedded placenta. DIAPH3 antibody [C1C3] , dilution: 1:100. 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB DIAPH3 Antibody (C-term)  western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the DIAPH3 antibody detected the DIAPH3 protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 7 to 9 Days
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
Human Rabbit Un-conjugated IP, WB Immunoprecipitation of DIAPH3 transfected lysate using anti-DIAPH3 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with DIAPH3 purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of DIAPH3 expression in transfected 293T cell line by DIAPH3 MaxPab polyclonal antibody.Lane 1: DIAPH3 transfected lysate(98.1 KDa).Lane 2: Non-transfected lysate. 100 μL Log in to see 9 Days
Human Goat Un-conjugated ELISA   100 μg Log in to see 7 to 9 Days

DIAPH3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)

Mouse (Murine)

Human , , ,
, ,
, , , , ,

Top referenced anti-DIAPH3 Antibodies

  1. Human Polyclonal DIAPH3 Primary Antibody for EIA, WB - ABIN951910 : DeWard, Alberts: Ubiquitin-mediated degradation of the formin mDia2 upon completion of cell division. in The Journal of biological chemistry 2009 (PubMed)
    Show all 4 references for ABIN951910

  2. Human Polyclonal DIAPH3 Primary Antibody for ELISA, WB - ABIN566471 : Kyrkou, Soufi, Bahtz, Ferguson, Bai, Parton, Hoffmann, Zerial, Fotsis, Murphy: RhoD participates in the regulation of cell-cycle progression and centrosome duplication. in Oncogene 2013 (PubMed)

  3. Human Polyclonal DIAPH3 Primary Antibody for ELISA - ABIN449532 : Yang, Czech, Gerboth, Kojima, Scita, Svitkina: Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells. in PLoS biology 2007 (PubMed)

More Antibodies against DIAPH3 Interaction Partners

Mouse (Murine) Diaphanous Homolog 3 (Drosophila) (DIAPH3) interaction partners

  1. Ineffective erythropoiesis caused by binucleated late-stage erythroblasts in mDia2 hematopoietic specific knockout mice.

  2. the interactome of auto-inhibited and constitutively active mDia2, is reported.

  3. mDia2-deficient erythroid cells differentiate normally, though in a delayed manner, but exhibit cytokinesis failure with decreased accumulation of F-actin in the cleavage furrow during late differentiation from proerythroblasts

  4. Diaphanous homolog 3 (Diap3) overexpression causes progressive hearing loss and inner hair cell defects in a transgenic mouse model of human deafness.

  5. Dia1 (show CYB5R3 Antibodies) and Dia2 are dynamic components of meiotic spindle and pole complex during meiotic maturation of oocytes.

  6. Microtubules strongly inhibit actin polymerization by mDia2.

  7. Results indicate that ROCK-dependent phosphorylation of the mDia2 DAD is an important determinant of mDia2 activity and that this signalling mechanism affects actin polymerization and smooth muscle cell-specific gene expression.

  8. Results show that targeting of mDia2 to the cleavage furrow requires not only its binding to RhoA (show RHOA Antibodies) but also its diaphanous-inhibitory domain, and identify anillin (show ANLN Antibodies) as a novel mDia2 interaction partner.

  9. Int (show TSC22D3 Antibodies)roduction of the mDia2 inhibitor DIP/WISH/SPIN90 into ce (show DIAPH2 Antibodies)lls triggers non-apoptotic membrane blebbing. The results infer a role for mDia2 in (show ACTR2 Antibodies)the maintenance of actin networks supporting the cell cortex.

  10. the bundling activities of FRL1 and mDia2, while producing phenotypically similar bundles, differ in mechanistic detail

Human Diaphanous Homolog 3 (Drosophila) (DIAPH3) interaction partners

  1. we use a simple cellular system to examine fundamental features of formin (show FMN1 Antibodies)-mediated filopodial assembly, using constitutively active constructs of the formins mDia2 and FMNL3 (show FMNL3 Antibodies)

  2. results suggest that inhibition of MT stability arising from DIAPH3 downregulation enhances susceptibility to MT poisons, and that the DIAPH3 network potentially reports taxane sensitivity in human tumors

  3. Dia1 (show CYB5R3 Antibodies), Dia2 (show DIAPH2 Antibodies), and Dia3 (show DIAPH2 Antibodies) are involved in ErbB2 (show ERBB2 Antibodies)-dependent capture of microtubules at the cell leading edge and ErbB2 (show ERBB2 Antibodies)-driven guided migration.

  4. An mDia2/ROCK signaling axis regulates invasive egress from epithelial ovarian cancer spheroids.

  5. TGF-beta promotes association of mDia2 with actin stress fibers, which further drives stress fiber formation and myofibroblast differentiation

  6. In human tumours, DIAPH3 down-regulation was associated with aggressive or metastatic disease.

  7. isoform-selective actin assembly by DIAPH3 exerts specific and differentially regulated functions during cell adhesion and motility.

  8. the amino terminus of mDia2 serves as a coincidence detection module, directing mDia2 to the plasma membrane through interactions with phospholipids and activated Rif

  9. These findings reveal a key role for mDia3 and its regulation by Aurora B (show AURKB Antibodies) phosphorylation in achieving proper stable kinetochore microtubule attachment.

  10. These studies further suggest that Rho GTPases significantly influence the activity of mDia family formins in driving cellular membrane remodeling through the regulation of actin dynamics.

DIAPH3 Antigen Profile

Protein Summary

This gene encodes a member of the diaphanous subfamily of the formin family. Members of this family are involved in actin remodeling and regulate cell movement and adhesion. Mutations in this gene are associated with autosomal dominant auditory neuropathy 1. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DIAPH3

  • diaphanous-related formin 3 (Diaph3) antibody
  • diaphanous homolog 3 (Drosophila) (DIAPH3) antibody
  • diaphanous-related formin 3 (DIAPH3) antibody
  • diaphanous homolog 3 (Drosophila) (Diap3) antibody
  • 4930417P13Rik antibody
  • AN antibody
  • AUNA1 antibody
  • DIA2 antibody
  • diap3 antibody
  • Diaph3 antibody
  • DRF3 antibody
  • mDia2 antibody
  • mKIAA4117 antibody
  • NSDAN antibody
  • p134MDia2 antibody

Protein level used designations for DIAPH3

diaphanous homolog 3 , protein diaphanous homolog 3 , diaphanous homolog 3 (Drosophila) , protein diaphanous homolog 3-like , diaphanous-related formin , diaphanous-related formin-3

290396 Rattus norvegicus
418824 Gallus gallus
100174272 Pongo abelii
485474 Canis lupus familiaris
525628 Bos taurus
452752 Pan troglodytes
100051814 Equus caballus
100011744 Monodelphis domestica
100475459 Ailuropoda melanoleuca
100517419 Sus scrofa
56419 Mus musculus
81624 Homo sapiens
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