DIAPH3 antibody (Center)

Catalog No. ABIN2855508

Product Details anti-DIAPH3 Antibody

Target: DIAPH3 (Diaphanous Homolog 3 (Drosophila) (DIAPH3))

Binding Specificity: Center

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIAPH3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Cow (Bovine)

Cross-Reactivity (Details): Bovine (90 %)

Characteristics: Rabbit polyclonal antibody to DIAPH3 (diaphanous homolog 3 (Drosophila))
DIAPH3 antibody [C1C3]

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human DIAPH3. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000*

Comment:

Positive Control: Target recombinant protein

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for DIAPH3

Target: DIAPH3 (Diaphanous Homolog 3 (Drosophila) (DIAPH3))

Alternative Name: DIAPH3 (DIAPH3 Products)

Synonyms: Diap3 antibody, DIAP3 antibody, DIAPH3 antibody, 4930417P13Rik antibody, Dia2 antibody, Diaph3 antibody, Drf3 antibody, mDia2 antibody, mKIAA4117 antibody, p134MDia2 antibody, AN antibody, AUNA1 antibody, DIA2 antibody, DRF3 antibody, NSDAN antibody, diap3 antibody, diaphanous-related formin 3 antibody, diaphanous related formin 3 antibody, diaphanous homolog 3 (Drosophila) antibody, Diaph3 antibody, DIAPH3 antibody

Background: Binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics.

Molecular Weight: 137 kDa

Gene ID: 81624