You are viewing an incomplete version of our website. Please click to reload the website as full version.

Dipeptidyl-Peptidase 4 Proteins (DPP4)

The protein encoded by DPP4 is a homodimeric integral membrane gelatinase belonging to the serine protease family. Additionally we are shipping DPP4 Antibodies (418) and DPP4 Kits (88) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DPP4 1803 P27487
DPP4 13482 P28843
DPP4 25253 P14740
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top DPP4 Proteins at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human Fc Tag 50 μg Log in to see 2 to 3 Days
$374.00
Details
HOST_HEK-293 Cells Human Un-conjugated 50 μg Log in to see 2 to 3 Days
$451.00
Details
HOST_Human Cells Human Fc Tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Cynomolgus Fc Tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Human His tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Mouse Fc Tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Cynomolgus Un-conjugated 10 μg Log in to see 16 Days
$250.80
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details

DPP4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , , ,
, , ,
Mouse (Murine) , ,
, ,
Rat (Rattus) ,

Top referenced DPP4 Proteins

  1. Human DPP4 Protein expressed in Human Cells - ABIN2003230 : Morimoto, Lord, Zhang, Duke-Cohan, Letvin, Schlossman: Role of CD26/dipeptidyl peptidase IV in human immunodeficiency virus type 1 infection and apoptosis. in Proceedings of the National Academy of Sciences of the United States of America 1994 (PubMed)
    Show all 5 references for ABIN2003230

  2. Cynomolgus DPP4 Protein expressed in Human Cells - ABIN2009956 : Hinke, Pospisilik, Demuth, Mannhart, Kühn-Wache, Hoffmann, Nishimura, Pederson, McIntosh: Dipeptidyl peptidase IV (DPIV/CD26) degradation of glucagon. Characterization of glucagon degradation products and DPIV-resistant analogs. in The Journal of biological chemistry 2000 (PubMed)
    Show all 5 references for ABIN2009956

  3. Human DPP4 Protein expressed in HEK-293 Cells - ABIN2180984 : Endo, Harigae, Nagai, Fujie, Meguro, Watanabe, Furuyama, Kameoka, Okuda, Hayashi: Two chronic myelogenous leukaemia cell lines which represent different stages of erythroid differentiation. in British journal of haematology 1994 (PubMed)
    Show all 5 references for ABIN2180984

  4. Mouse (Murine) DPP4 Protein expressed in Human Cells - ABIN2008231 : Reinhold, Kähne, Steinbrecher, Wrenger, Neubert, Ansorge, Brocke: The role of dipeptidyl peptidase IV (DP IV) enzymatic activity in T cell activation and autoimmunity. in Biological chemistry 2002 (PubMed)
    Show all 5 references for ABIN2008231

  5. Cynomolgus DPP4 Protein expressed in Human Cells - ABIN2009954 : Steinbrecher, Reinhold, Quigley, Gado, Tresser, Izikson, Born, Faust, Neubert, Martin, Ansorge, Brocke: Targeting dipeptidyl peptidase IV (CD26) suppresses autoimmune encephalomyelitis and up-regulates TGF-beta 1 secretion in vivo. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 5 references for ABIN2009954

  6. Human DPP4 Protein expressed in HEK-293 Cells - ABIN2180980 : Kameoka, Tanaka, Nojima, Schlossman, Morimoto: Direct association of adenosine deaminase with a T cell activation antigen, CD26. in Science (New York, N.Y.) 1993 (PubMed)
    Show all 5 references for ABIN2180980

  7. Human DPP4 Protein expressed in Human Cells - ABIN2003228 : Pro, Dang: CD26/dipeptidyl peptidase IV and its role in cancer. in Histology and histopathology 2004 (PubMed)
    Show all 4 references for ABIN2003228

More Proteins for Dipeptidyl-Peptidase 4 (DPP4) Interaction Partners

Human Dipeptidyl-Peptidase 4 (DPP4) interaction partners

  1. NPY is efficiently cleaved by FAP indicating a potential function for FAP in neuropeptide regulation within liver and cancer biology.

  2. degradomic study highlights cell-contextual proteolysis by FAPalpha with distinct positional profiles. Generally, our findings link FAPalpha to key aspects of CAF (show KAT2B Proteins) biology and attribute an important role in tumor-stroma interaction to FAPalpha

  3. Results identified heart expression of DPP4 to be coordinated with a gene expression signature characteristic for whole blood proliferation, potentially impacting peripheral stem cell mobilization.

  4. decreased T-cell expression and lower plasma levels in Indian patients with Post Kala-azar Dermal Leishmaniasis

  5. The effect of the DPP-4 inhibitor alogliptin on HbA1c.

  6. Data suggest that a DNA vaccine targeting human fibroblast activation protein alpha (show FAP Proteins) (FAPalpha) may be an attractive and effective cancer immunotherapy strategy.

  7. In this study, we show for the first time the expression of FAP in activated fibroblasts after MI and its activation by TGFbeta1 (show TGFB1 Proteins). Effects of FAP on fibroblast migration and gelatinolytic activity indicate a potential role in cardiac wound healing

  8. Lack of DPP4 expression may be the primary cause of limited MERS-CoV replication in the human upper respiratory tract and hence restrict transmission.

  9. FAP is expressed by activated, collagen-synthesizing fibroblasts, but not by inactive fibroblasts or fully differentiated myofibroblasts and non-fibroblast cells in the infarct.

  10. Loss of DPP4 is associated with Multi-Organ Damage in Human Dipeptidyl Peptidase 4 Transgenic Mice Infected with Middle East Respiratory Syndrome-Coronavirus.

Cow (Bovine) Dipeptidyl-Peptidase 4 (DPP4) interaction partners

  1. Results describe a proline-rich cytokine from neurosecretory granules that represents a new natural substrate for Dipeptidyl Peptidase IV (DPPIV).

  2. Data demonstrate that dipeptidyl peptidase II (show DPP7 Proteins) can form a complex with adenosine deaminase (show ADA Proteins), but with one order of magnitude higher dissociation constant than that of DPPIV.

Pig (Porcine) Dipeptidyl-Peptidase 4 (DPP4) interaction partners

  1. This study shows that porcine DPP-IV is generally inhibited with greater potency by protein-derived peptides than is the human enzyme

  2. DPP-IV from porcine kidney cortex was characterized.

  3. Neutral endopeptidase 24.11 (show MME Proteins) and DPP-IV is superior to DPP-IV inhibition alone in preserving intact GLP-1 (show GCG Proteins), which implies possibility that the combination has therapeutic potential.

  4. Results describe the distribution of dipeptidyl peptidase IV-like activity enzymes in porcine tissue sections by RT-PCR.

Mouse (Murine) Dipeptidyl-Peptidase 4 (DPP4) interaction partners

  1. Data suggest that pharmacological stimulation of serotonin 5Ht1b (show HTR1B Proteins) receptor enhances up-regulation of plasma Glp1 (glucagon-like peptide 1 (show GCG Proteins)) induced by Dpp4 (dipeptidylpeptidase 4) inhibition independently of feeding and also improves glucose tolerance.

  2. Young euglycemic Dpp4 KO mice showed a cardioprotective response after transverse aortic constriction or doxorubicin administration, with reduced fibrosis; however, cardiac mRNA analysis revealed increased expression of inflammation-related transcripts.

  3. Dipeptidyl peptidase-4 inhibition by gemigliptin exerts a preventative effect on the proliferation and migration of VSMCs via Nrf2 (show NFE2L2 Proteins).

  4. The present study reveals the activation of autophagy to mediate the anti-diabetic effect of GLP-1 (show GCG Proteins).

  5. These results indicate that DPP-4 inhibitors pleiotropically exert a direct renoprotective effect, and may serve as an additional therapeutic strategy to protect proximal tubular cells against proteinuria in patients with diabetic nephropathy.

  6. DPP-4 and integrin beta1 interactions regulate key endothelial cell signal transduction in both physiological and pathological conditions including endothelial mesenchymal transformation.

  7. sDPP-4 enhances inflammatory actions via TLR pathway, while DPP-4 inhibition with either an enzymatic or binding inhibitor has anti-inflammatory effects.

  8. DPP4i restores cardiac remodeling and apoptosis caused by the pathological decline in circulating GLP-1 in response to pressure overload. EPAC1 is essential for cardiomyocyte survival via the cAMP/Rap1 activation independently of PKA.

  9. Combination of DPP-4 inhibitor and PPARgamma (show PPARG Proteins) agonist exerts protective effects on pancreatic beta-cells in diabetic db/db (show LEPR Proteins) mice through the augmentation of IRS-2 (show IRS2 Proteins) expression

  10. DPP4 inhibiton appeared to suppress neointimal formation by inhibiting inflammation, independently of its effects on glucose or cholesterol metabolism in atherogenic LDL receptor (show LDLR Proteins) KO mice.

DPP4 Protein Profile

Protein Summary

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.

Gene names and symbols associated with Dipeptidyl-Peptidase 4 Proteins (DPP4)

  • dipeptidyl-peptidase 9 (dpp9)
  • dipeptidyl-peptidase 4 (dpp4)
  • dipeptidyl-peptidase 4 (DPP4)
  • prolyl oligopeptidase family protein (AT5G24260)
  • dipeptidylpeptidase 4 (Dpp4)
  • fibroblast activation protein, alpha (FAP)
  • ADABP protein
  • ADCP2 protein
  • Cd26 protein
  • Dpp-4 protein
  • DPP4 protein
  • DPPIV protein
  • FAPA protein
  • im:7145318 protein
  • MGC81966 protein
  • MOP9.8 protein
  • MOP9_8 protein
  • si:ch73-2d23.3 protein
  • THAM protein
  • TP103 protein
  • zgc:152900 protein

Protein level used designations for Dipeptidyl-Peptidase 4 Proteins (DPP4)

dipeptidyl peptidase 9 , dipeptidyl-peptidase 4 , dipeptidyl-peptidase IV , dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) , dipeptidylpeptidase IV , dipeptidyl peptidase 4 , ADCP-2 , DPP IV , T-cell activation antigen CD26 , adenosine deaminase complexing protein 2 , dipeptidyl peptidase IV , dipeptidylpeptidase 4 , dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2) , ACT3 , ADCP-I , WC10 , activation molecule 3 , adenosine deaminase complexing protein , dipeptidyl-peptidase iv , thymocyte-activating molecule , GP110 glycoprotein , bile canaliculus domain-specific membrane glycoprotein , 170 kDa melanoma membrane-bound gelatinase , integral membrane serine protease , seprase

GENE ID SPECIES
768170 Danio rerio
397888 Xenopus laevis
459689 Pan troglodytes
478767 Canis lupus familiaris
654491 Macaca mulatta
832493 Arabidopsis thaliana
8955655 Sphingobium japonicum UT26S
100022348 Monodelphis domestica
100170324 Ovis aries
100173322 Pongo abelii
100605220 Nomascus leucogenys
1803 Homo sapiens
281122 Bos taurus
397492 Sus scrofa
493787 Felis catus
100301982 Danio rerio
13482 Mus musculus
25253 Rattus norvegicus
2191 Homo sapiens
Selected quality suppliers for DPP4 Proteins (DPP4)
Did you look for something else?