DRAP1 Proteins
(DR1-Associated Protein 1 (Negative Cofactor 2 Alpha) (DRAP1))
Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq, Jul 2008].
| Catalog no. | Product | Reactivity | Host / Clonality | Application | Price & lead time |
|---|---|---|---|---|---|
| DRAP1 Protein (AA 1-205) (GST tag) | Human | Wheat germ |
|
$475.39
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| DRAP1 Protein (AA 4-198, partial) (GST tag) | Human | Escherichia coli (E. coli) |
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$493.16
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|
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| DRAP1 Protein (Myc-DYKDDDDK Tag) | Human | HEK-293 Cells |
|
$1,112.40
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|
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| DRAP1 Protein (AA 2-205) (His tag) | Cow | Yeast |
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$1,216.24
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|
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| DRAP1 Protein (AA 2-205) (His tag) | Rat | Yeast |
|
$1,216.24
View price
|
Protein
- AP (Affinity Purification: Listed application)
- AA (Antibody Array: Listed application)
- ELISA (ELISA: Listed application)
- WB (Western Blotting: Listed application)
- Origin
- Human
- Host
- Wheat germ
- Protein Type
- Recombinant
Catalog No. ABIN1352006
$475.39
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
(More quantities available)
Shipping to:
United States
Delivery in 11 to 14 Business Days
Protein
- SDS (SDS-PAGE: Validation image available)
- ELISA (ELISA: Listed application)
5 references - Origin
- Human
- Host
- Escherichia coli (E. coli)
- Protein Type
- Recombinant
- Purity
- 90 %
Catalog No. ABIN1046948
$493.16
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 13 to 17 Business Days
Protein
- WB (Western Blotting: Validation image available)
- AbP (Antibody Production: Listed application)
- STD (Standard: Listed application)
- Origin
- Human
- Host
- HEK-293 Cells
- Protein Type
- Recombinant
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
Catalog No. ABIN2719758
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to:
United States
Delivery in 11 to 12 Business Days
Protein
- ELISA (ELISA: Listed application)
- Origin
- Cow
- Host
- Yeast
- Protein Type
- Recombinant
- Purity
- > 90 %
Catalog No. ABIN7588632
$1,216.24
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 60 to 72 Business Days
Protein
- ELISA (ELISA: Listed application)
- Origin
- Rat
- Host
- Yeast
- Protein Type
- Recombinant
- Purity
- > 90 %
Catalog No. ABIN7584163
$1,216.24
Plus shipping costs $50.00
100 μg
(More quantities available)
Shipping to:
United States
Delivery in 60 to 72 Business Days
Latest Publications for our DRAP1 Proteins
: "Initial characterization of the human central proteome." in: BMC systems biology, Vol. 5, pp. 17, (2011) (PubMed).
: "NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein." in: Molecular and cellular biology, Vol. 24, Issue 22, pp. 10072-82, (2004) (PubMed).
: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).
: "A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains." in: The EMBO journal, Vol. 15, Issue 12, pp. 3105-16, (1996) (PubMed).
: "Requirement of a corepressor for Dr1-mediated repression of transcription." in: Genes & development, Vol. 10, Issue 8, pp. 1033-48, (1996) (PubMed).
: "NC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding protein." in: Molecular and cellular biology, Vol. 24, Issue 22, pp. 10072-82, (2004) (PubMed).
: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).
: "A mechanism for repression of class II gene transcription through specific binding of NC2 to TBP-promoter complexes via heterodimeric histone fold domains." in: The EMBO journal, Vol. 15, Issue 12, pp. 3105-16, (1996) (PubMed).
: "Requirement of a corepressor for Dr1-mediated repression of transcription." in: Genes & development, Vol. 10, Issue 8, pp. 1033-48, (1996) (PubMed).
Aliases for DRAP1 Proteins
DR1-associated protein 1 (negative cofactor 2 alpha) (drap1) ProteinsDR1 associated protein 1 (DRAP1) Proteins
Dr1 associated protein 1 (negative cofactor 2 alpha) (Drap1) Proteins
Dr1 associated protein 1 (Drap1) Proteins
2310074H19Rik Proteins
DRAP1 Proteins
fb26e10 Proteins
NC2-alpha Proteins
wu:fb26e10 Proteins
zgc:56003 Proteins
zgc:77337 Proteins
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