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Dynein, Cytoplasmic 1, Heavy Chain 1 (DYNC1H1) ELISA Kits

Dyneins are a group of microtubule-activated ATPases that function as molecular motors. Additionally we are shipping DYNC1H1 Antibodies (21) and DYNC1H1 Proteins (2) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
DYNC1H1 29489 P38650
DYNC1H1 13424 Q9JHU4
DYNC1H1 1778 Q14204
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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.113 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
  96 Tests Log in to see 16 to 21 Days
Guinea Pig
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More ELISA Kits for DYNC1H1 Interaction Partners

Zebrafish Dynein, Cytoplasmic 1, Heavy Chain 1 (DYNC1H1) interaction partners

  1. Data show that basal body docking was unaffected in dynein 1 (dync1h1) mutation, but rab GTP-binding protein Rab6 expression was reduced.

  2. dync1h1 promotes axon ensheathment and myelin gene expression.

  3. This study provided evidence that Dync1h1 is also required for efficient myelination of peripheral axons by Schwann cells, perhaps by facilitating signal transduction necessary for myelination.

Mouse (Murine) Dynein, Cytoplasmic 1, Heavy Chain 1 (DYNC1H1) interaction partners

  1. These data unveil a previously unrecognized role for the dynein-dynactin (show DCTN1 ELISA Kits) motor complex in osteoclast formation and function.

  2. The Loa heterozygote phenotype is morphometrically depleted; in addition to dendritic axonal defects, the Loa mutation in a mouse model for mixed motor-sensory loss considers the entire neuraxis and is not a model for sensory loss.

  3. Snapin (show SNAPIN ELISA Kits)-dynein coupling is one of the primary mechanisms driving BDNF (show BDNF ELISA Kits)-TrkB (show NTRK2 ELISA Kits) retrograde transport, thus providing mechanistic insights into the regulation of neuronal growth and survival.

  4. Data show that amyloid precursor protein (APP (show APP ELISA Kits)) levels are well-correlated with the amount of the light chain of kinesin-1 (KLC1 (show KLC1 ELISA Kits)).

  5. neuromuscular junction defects in mice with mutation of dynein heavy chain 1

  6. Results provide genetic evidence that dynein plays a key role in lipid metabolism and thermogenesis.

  7. These results suggest a potential role for the dynein tail in motor function, and provide direct evidence for a link between single-motor processivity and disease.

  8. Impairment of retrograde transport by knockdown of DHC1 or BicD1 (show BICD1 ELISA Kits) inhibits stress-granule formation and P-body growth upon stress.

  9. results show that missense point mutations result in progressive motor neuron degeneration (show CLN8 ELISA Kits) in heterozygous mice, and in homozygotes this is accompanied by the formation of Lewy-like inclusion bodies, resembling key features of human pathology

  10. Results describe the gene encoding the dynein axonemal light intermediate chain Dnali1 (show DNALI1 ELISA Kits), and suggest that the C-terminal part of the cytoplasmic dynein heavy chain 1 is a putative interacting polypeptide of Dnali1 (show DNALI1 ELISA Kits).

Human Dynein, Cytoplasmic 1, Heavy Chain 1 (DYNC1H1) interaction partners

  1. Our findings suggest that DYNC1H1 variants can cause not only lower, but also upper motor neuron disease.

  2. The mutations in DYNC1H1 increase the interaction with its adaptor BICD2 (show BICD2 ELISA Kits).

  3. Dynactin functions as both a dynamic tether and brake during dynein-driven motility.

  4. These findings also reveal a possible new target for Amblyomin-X, i.e., dynein, and may serve as a tool for investigating tumor cell death associated with proteasome inhibition.

  5. These results reveal that conformational changes involving hexon hypervariable region 1 are the basis for a novel viral mechanism controlling capsid transport to the nucleus by dynein.

  6. Report expands the clinical spectrum of DYNC1H1-related spinal muscular atrophy to include generalized arthrogryposis

  7. Authors propose that Snapin connects chlamydial inclusions with the microtubule network by interacting with both Chlamydia psittaci IncB and dynein.

  8. Authors find that pharmacological or small interfering RNA (siRNA)-mediated inhibition of cytoplasmic dynein or the kinesin 1 heavy chain KIF5B (show KIF5B ELISA Kits) delays HIV-1 uncoating.

  9. single dynein molecules in the cell are autoinhibited through intramolecular head-head stacking

  10. Our results expand the set of pathological mutations in DYNC1H1, reinforce the role of cytoplasmic dynein in disorders of neuronal migration, and provide evidence for a syndrome including spinal nerve degeneration and brain developmental problems.

DYNC1H1 Antigen Profile

Antigen Summary

Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family.

Gene names and symbols associated with DYNC1H1

  • dynein, cytoplasmic 1, heavy chain 1 (dync1h1) antibody
  • dynein, cytoplasmic 1, heavy chain 1 (DYNC1H1) antibody
  • dynein cytoplasmic 1 heavy chain 1 (Dync1h1) antibody
  • 9930018I23Rik antibody
  • AI894280 antibody
  • DHC1 antibody
  • DHC1a antibody
  • DNCH1 antibody
  • Dnchc1 antibody
  • DNCL antibody
  • Dnec1 antibody
  • DNECL antibody
  • DYHC antibody
  • fk70a07 antibody
  • HL-3 antibody
  • Loa antibody
  • MAP1C antibody
  • mKIAA0325 antibody
  • P22 antibody
  • SMALED1 antibody
  • Swl antibody
  • wu:fk70a07 antibody

Protein level used designations for DYNC1H1

cytoplasmic dynein 1 heavy chain 1 , cytoplasmic dynein , MAP 1C , cytoplasmic dynein heavy chain 1 , dynein heavy chain, cytosolic , dynein, cytoplasmic, heavy chain 1 , dynein heavy chain, retrograde transport , legs at odd angle , sprawling , dynein, cytoplasmic, heavy polypeptide 1

335110 Danio rerio
423461 Gallus gallus
537748 Bos taurus
100126211 Xenopus (Silurana) tropicalis
29489 Rattus norvegicus
13424 Mus musculus
1778 Homo sapiens
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