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anti-Endogenous Retrovirus Group W, Member 1 (ERVW-1) Antibodies

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. Additionally we are shipping ERVW-1 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ERVW-1 30816 Q9UQF0
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Top anti-ERVW-1 Antibodies at

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ERVWE1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-Syncytin 1/HERV Polyclonal Antibody, Unconjugated (ABIN682318) followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged ERVWE1 is approximately 0.1ng/ml as a capture antibody. 100 μg Log in to see 9 Days
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated WB ERVWE1 Antibody (C-term)  western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the ERVWE1 antibody detected the ERVWE1 protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days

ERVW-1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
, , , , ,
Mouse (Murine) ,

Rat (Rattus) ,

Top referenced anti-ERVW-1 Antibodies

  1. Human Polyclonal ERVW-1 Primary Antibody for EIA, WB - ABIN357849 : Oluwole, Yao, Conradi, Kristensson, Karlsson: Elevated levels of transcripts encoding a human retroviral envelope protein (syncytin) in muscles from patients with motor neuron disease. in Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 2007 (PubMed)
    Show all 3 references for ABIN357849

  2. Human Monoclonal ERVW-1 Primary Antibody for ELISA - ABIN526263 : Ruebner, Strissel, Langbein, Fahlbusch, Wachter, Faschingbauer, Beckmann, Strick: Impaired cell fusion and differentiation in placentae from patients with intrauterine growth restriction correlate with reduced levels of HERV envelope genes. in Journal of molecular medicine (Berlin, Germany) 2010 (PubMed)
    Show all 2 references for ABIN526263

  3. Human Polyclonal ERVW-1 Primary Antibody for IHC (p), WB - ABIN682318 : Díaz-Carballo, Acikelli, Klein, Jastrow, Dammann, Wyganowski, Guemues, Gustmann, Bardenheuer, Malak, Tefett, Khosrawipour, Giger-Pabst, Tannapfel, Strumberg: Therapeutic potential of antiviral drugs targeting chemorefractory colorectal adenocarcinoma cells overexpressing endogenous retroviral elements. in Journal of experimental & clinical cancer research : CR 2015 (PubMed)

  4. Human Polyclonal ERVW-1 Primary Antibody for WB - ABIN2782821 : Mangeney, Renard, Schlecht-Louf, Bouallaga, Heidmann, Letzelter, Richaud, Ducos, Heidmann: Placental syncytins: Genetic disjunction between the fusogenic and immunosuppressive activity of retroviral envelope proteins. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)

More Antibodies against ERVW-1 Interaction Partners

Human Endogenous Retrovirus Group W, Member 1 (ERVW-1) interaction partners

  1. Syncytin-1 and ASCT-2 (show SLC1A5 Antibodies) is localized at the acrosomal region and equatorial segment of the spermatozoa.

  2. The effect of ETS1 (show ETS1 Antibodies) on syncytialization of trophoblasts likely results, at least in part, from inhibition of syncytin expression.

  3. These results indicated that aberrant hypermethylation is involved in downregulation of syncytin-1, and epigenetic alterations may play a significant role in the development of preeclampsia

  4. Exosomes from cultured primary villous cytotrophoblasts and sera of pregnant women have syncytin-1 on their surfaces. It acts on cellular binding and uptake of exosomes.

  5. Increased trophoblast apoptosis and altered expression levels of syncytin-1, calpain 1 (show CAPN1 Antibodies), and AIF (show AIFM1 Antibodies) is observed in preeclamptic placentas.

  6. Syncytin-1 overexpression may be an indicator of urothelial cell carcinoma risk.

  7. Influenza A virus infection transactivated ERVWE1 by increasing the transcription of GCM1 (show GCM1 Antibodies).

  8. Overexpression of HERV-W envelope gene elevated the levels of SK3 (show KCNN3 Antibodies) channel in neuroblastoma (show ARHGEF16 Antibodies) cells.

  9. Syncytin-1 knockdown significantly inhibited BeWo cell growth and DNA synthesis and Syncytin-1 could promote the G1/S transition through p15 (show CDKN2B Antibodies) and CDK4 (show CDK4 Antibodies).

  10. This study linked decreased Syncytin-1 expression to an epigenetic hypermethylation of the entire promoter of ERVW-1.

ERVW-1 Antigen Profile

Protein Summary

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with ERVW-1

  • endogenous retrovirus group W, member 1 (ERVW-1) antibody
  • ENV antibody
  • ENVW antibody
  • ERVWE1 antibody
  • HERV-7q antibody
  • HERV-W-ENV antibody
  • HERV7Q antibody
  • HERVW antibody
  • HERVWENV antibody

Protein level used designations for ERVW-1

HERV-7q envelope protein , HERV-W Env glycoprotein , HERV-W envelope protein , HERV-W_7q21.2 provirus ancestral Env polyprotein , HERV-W{7q21.1} provirus ancestral Env polyprotein , HERV-tryptophan envelope protein , endogenous retroviral family W, env(C7), member 1 , endogenous retrovirus group W member 1 , env-W , envelope glycoprotein , envelope polyprotein gPr73 , envelope protein , enverin , human endogenous retrovirus W envC7-1 envelope protein , syncytin A , syncytin-1

30816 Homo sapiens
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