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anti-Eomesodermin (EOMES) Antibodies

EOMES encodes a member of a conserved protein family that shares a common DNA-binding domain, the T-box. Additionally we are shipping EOMES Kits (5) and EOMES Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EOMES 8320 O95936
EOMES 316052  
EOMES 13813 O54839
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Top anti-EOMES Antibodies at

Showing 10 out of 81 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-EOMES Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate Human HepG2 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated WB WB Suggested Anti-EOMES Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: NCI-H226 cell lysate 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 10 to 12 Days
Mouse Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Mouse Rabbit Un-conjugated IHC, WB WB Suggested Anti-Eomes  Antibody Titration: 0.2-1 µg/mL  Positive Control: Mouse Muscle 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated WB EOMES Antibody (N-term) (ABIN1881298) western blot analysis in A375 cell line lysates (35 µg/lane). This demonstrates the EOMES antibody detected the EOMES protein (arrow). 400 μL Log in to see 10 to 11 Days
Human Mouse Un-conjugated FACS, ICC, WB Detection of EOMES in Differentiated BG01VHuman Cells by Flow Cytometry. BG01V human embryonic stem cells differentiated to mesendoderm were stained with Mouse Anti-Human EOMES Monoclonal Antibody. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. EOMES in Mesodermally Differentiated BG01V Human Stem Cells. EOMES was detected in immersion fixed BG01V human embryonic stem cells differentiated into mesoderm using Human EOMES Monoclonal Antibody. Specific staining was localized to nuclei. 100 μg Log in to see 6 to 7 Days
Human Rabbit Un-conjugated IHC, IHC (p) Immunocytochemistry/Immunofluorescence: EOMES Antibody [NBP1-80699] - Staining of human cell line A-431 shows positivity in nucleus. Immunohistochemistry-Paraffin: EOMES Antibody [NBP1-80699] - Staining of human kidney shows strong cytoplasmic positivity in subsets of tubules. 0.1 mL Log in to see 5 to 7 Days
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 14 Days
Human Rabbit Un-conjugated IHC (p), WB Human Thymus (formalin-fixed, paraffin-embedded) stained with EOMES antibody ABIN214110 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days

EOMES Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
, , ,
, , , , , , , , , , , , ,
Rat (Rattus)

Mouse (Murine) ,

Top referenced anti-EOMES Antibodies

  1. Human Polyclonal EOMES Primary Antibody for EIA, WB - ABIN4620401 : Intlekofer, Takemoto, Wherry, Longworth, Northrup, Palanivel, Mullen, Gasink, Kaech, Miller, Gapin, Ryan, Russ, Lindsten, Orange, Goldrath, Ahmed, Reiner: Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. in Nature immunology 2005 (PubMed)
    Show all 4 references for ABIN4620401

  2. Human Polyclonal EOMES Primary Antibody for WB - ABIN1881298 : Wang, Ge, Xue, Li: [Role of transcription factor T-bet and Eomes in IFN-gamma secretion of different human T cell subsets]. in Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 2010 (PubMed)
    Show all 3 references for ABIN1881298

  3. Human Monoclonal EOMES Primary Antibody for FACS, ICC - ABIN4900372 : Latos, Sienerth, Murray, Senner, Muto, Ikawa, Oxley, Burge, Cox, Hemberger: Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks. in Genes & development 2015 (PubMed)

  4. Human Polyclonal EOMES Primary Antibody for ICC, IF - ABIN4308348 : Mosenson, Zloza, Nieland, Garrett-Mayer, Eby, Huelsmann, Kumar, Denman, Lacek, Kohlhapp, Alamiri, Hughes, Bines, Kaufman, Overbeck, Mehrotra, Hernandez, Nishimura, Guevara-Patino, Le Poole: Mutant HSP70 reverses autoimmune depigmentation in vitiligo. in Science translational medicine 2013 (PubMed)

  5. Cow (Bovine) Polyclonal EOMES Primary Antibody for WB - ABIN2780686 : Baala, Briault, Etchevers, Laumonnier, Natiq, Amiel, Boddaert, Picard, Sbiti, Asermouh, Attié-Bitach, Encha-Razavi, Munnich, Sefiani, Lyonnet: Homozygous silencing of T-box transcription factor EOMES leads to microcephaly with polymicrogyria and corpus callosum agenesis. in Nature genetics 2007 (PubMed)

More Antibodies against EOMES Interaction Partners

Zebrafish Eomesodermin (EOMES) interaction partners

  1. Smad2 (show SMAD2 Antibodies) and Eomesodermin a (Eomesa) bind common genomic regions proximal to genes involved in mesoderm and endoderm formation, suggesting Eomesa forms a general component of the Smad2 (show SMAD2 Antibodies) signalling complex in zebrafish.

  2. Eomesa has a strictly maternal role in the initiation of epiboly, and is required for normal expression of the endoderm markers sox32, bon and og9x; however it is not essential for endoderm formation.

  3. Eomes is a Nodal-transducing factor that acts, directly and indirectly, in concert with FoxH1 (show FOXH1 Antibodies) to carry out all Nodal-dependent processes during early mesendoderm specification.

  4. Eomes plays a role in specifying the embryonic organizer.

  5. regulates the expression of a zygotic homeobox (show PRRX1 Antibodies) transcription factor mtx2 (show MTX2 Antibodies)

  6. Results suggest that eomesodermin promotes endoderm induction in marginal blastomeres by facilitating the assembly of a transcriptional activating complex on the casanova promoter.

  7. These results suggest that both Eomes genes are involved in the zebrafish immune response, particularly in lymphocyte function as has been found in mammals.

Pig (Porcine) Eomesodermin (EOMES) interaction partners

  1. the expression of T-bet, Eomes and GATA-3 (show GATA3 Antibodies) in combination with additional differentiation molecules within CD4 (show CD4 Antibodies)+ and CD8beta+ T cell subsets from different organs of healthy pigs.

Human Eomesodermin (EOMES) interaction partners

  1. EOMES expression was low in multiple sclerosis (MS), and stable over time. The low EOMES/TBX21 phenotype in MS reflects cd56 (show NCAM1 Antibodies)+ cell dysregulation.

  2. we identified a higher Eomes mRNA expression as an independent good prognostic factor for OS and PFS in mRCC patients treated with sorafenib.

  3. Eomes(+) CD4(+) T cells are increased in the peripheral blood and cerebrospinal fluid from patients in a progressive state of multiple sclerosis.

  4. the level of T-bet and Eomesodermin, two T-box transcription factors regulating lymphocyte effector functions, is strongly reduced in NK cells from allogeneic hematopoietic stem cell transplantation recipients compared with healthy control subjects.

  5. This study showed that EOMES (rs2724509; flanking) associated with Alzheimer disease.

  6. This study supports the concept that poor human viral-specific CD8 (show CD8A Antibodies)(+) T cell functionality is due to an inverse expression balance between T-bet and Eomes

  7. Report a global loss of 5hmC identified three new genes (ECM1 (show ECM1 Antibodies), ATF5 (show ATF5 Antibodies), and EOMES) with potential anti-cancer functions that may promote the understanding of the molecular mechanisms of hepatocellular carcinoma development and progression.

  8. HHEX (show HHEX Antibodies) promotes hepatic specification by repressing EOMES expression.

  9. CD127 (show IL7R Antibodies) is downregulated at a transcriptional level in memory CD8 (show CD8A Antibodies) T cells in association with upregulation of Eomes expression in HIV infected patients.

  10. The autoimmune disease-associated transcription factors EOMES and TBX21 are dysregulated in multiple sclerosis and define a molecular subtype of disease.

Cow (Bovine) Eomesodermin (EOMES) interaction partners

  1. as conceptuses attach to the uterine epithelium, IFNT gene transcription is down-regulated by an increase in EOMES expression and EOMES-CREBBP (show CREBBP Antibodies) binding in the attached trophoblast cells.

Mouse (Murine) Eomesodermin (EOMES) interaction partners

  1. Results indicated that Eomes bound to the Ifng (show IFNG Antibodies) promoter and multiple conserved noncoding sequences in stimulation-dependent and stimulation-independent manners.

  2. Demonstrate by using the T-box brain-2(Cre) mouse line that progenitor cells derived cells contribute 67.5% of glutamatergic but not GABAergic or astrocytic cells to all cortical layers including the earliest generated subplate zone.

  3. a critical role for IRF4 (show IRF4 Antibodies) in regulating protective anti-viral CD8 (show CD8A Antibodies)+ T cell responses by ensuring a balanced ratio of T-bet to Eomes

  4. Eomes expression is a key determinant of conventional NK versus Type 1 helper Innate Lymphoid Cell maturation following lineage specification.

  5. T-cell-specific deletion of the Eomes gene remarkably ameliorates the late-onset experimental autoimmune encephalomyelitis.

  6. find that while stimulation of CD27 (show CD27 Antibodies) in isolation drives weak Eomesodermin(hi) T-bet(lo) CD8 (show CD8A Antibodies)(+) T-cell responses to OVA immunization

  7. The data identify a novel role for Eomes in CD4 (show CD4 Antibodies)+ T cells and indicate that Eomes expression may act by limiting Foxp3 (show FOXP3 Antibodies) induction, which may contribute to the association of EOMES to susceptibility to multiple sclerosis.

  8. type I interferon (show IFNA Antibodies) signalling in CD8 (show CD8A Antibodies)(+) T cells drives Eomes expression.

  9. TGF-beta (show TGFB1 Antibodies)/tbr2 receptor signaling pathway may be required for prevention of beta cell death after initial cell proliferation following pancreatectomy.

  10. Interleukin-4 (show IL4 Antibodies) regulates eomesodermin in CD8 (show CD8A Antibodies)+ T cell development and differentiation

EOMES Antigen Profile

Protein Summary

This gene encodes a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similiar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation.

Gene names and symbols associated with anti-Eomesodermin (EOMES) Antibodies

  • eomesodermin homolog (Xenopus laevis) (EOMES) antibody
  • eomesodermin (eomes) antibody
  • eomesodermin homolog a (eomesa) antibody
  • eomesodermin homolog (LOC100470077) antibody
  • eomesodermin (EOMES) antibody
  • eomesodermin homolog (LOC100545637) antibody
  • eomesodermin homolog (LOC100602343) antibody
  • eomesodermin homolog (LOC100622125) antibody
  • eomesodermin (Eomes) antibody
  • eomesodermin homolog (Xenopus laevis) (Eomes) antibody
  • C77258 antibody
  • eom antibody
  • eomes antibody
  • TBR-2 antibody
  • Tbr2 antibody
  • xeomes antibody

Protein level used designations for anti-Eomesodermin (EOMES) Antibodies

eomesodermin homolog (Xenopus laevis) , eomesodermin , eom-a , eomes1 , eomesodermin homolog , tbr2 , tbr2a , T-box brain protein 2 , T-brain-2

428443 Gallus gallus
470774 Pan troglodytes
100038065 Xenopus (Silurana) tropicalis
100051187 Equus caballus
100431463 Pongo abelii
100532741 Salmo salar
64603 Danio rerio
100470077 Ailuropoda melanoleuca
100524218 Sus scrofa
100545637 Meleagris gallopavo
100602343 Nomascus leucogenys
100622125 Sus scrofa
8320 Homo sapiens
485636 Canis lupus familiaris
316052 Rattus norvegicus
511947 Bos taurus
398065 Xenopus laevis
13813 Mus musculus
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