EOMES antibody (C-Term)

Catalog No. ABIN2779928

This Rabbit Polyclonal antibody specifically detects EOMES in WB and IHC. It exhibits reactivity toward Mouse, Rat, Cow, Dog and Guinea Pig.

Quick Overview for EOMES antibody (C-Term) (ABIN2779928)

Target: EOMES (Eomesodermin (EOMES))

Reactivity: Mouse, Rat, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EOMES antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-EOMES Antibody

Binding Specificity: C-Term

Purpose: Eomes Antibody - C-terminal region

Sequence: SSDSGVYNSA CKRKRLSPST PSNGNSPPIK CEDINTEEYS KDTSKGMGAY

Predicted Reactivity: Cow: 80%, Dog: 80%, Guinea Pig: 80%, Mouse: 100%, Rat: 87%

Characteristics: This is a rabbit polyclonal antibody against Eomes. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human Eomes

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP37036-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for EOMES

Target: EOMES (Eomesodermin (EOMES))

Alternative Name: Eomes

Background:

Background Information: Eomes functions as a transcriptional activator playing a crucial role during development. Eomes functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification.Eomes plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Eomes also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes.

Gene Name: Eomesodermin homolog (Xenopus laevis)

Alternative Symbols: Tbr, Tbr2, TBR-2, C77258

Protein Name: Eomesodermin homolog

Molecular Weight: 75kDa

Gene ID: 13813

NCBI Accession: NP_034266

UniProt: O54839

Pathways: Stem Cell Maintenance