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EPCAM encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. Additionally we are shipping EPCAM Proteins (46) and EPCAM Kits (35) and many more products for this protein.
Showing 10 out of 1021 products:
Human Monoclonal EPCAM Primary Antibody for IHC (fro), IF - ABIN111179
Balzar, Winter, de Boer, Litvinov: The biology of the 17-1A antigen (Ep-CAM). in Journal of molecular medicine (Berlin, Germany) 2000
Show all 11 references for ABIN111179
Human Monoclonal EPCAM Primary Antibody for IHC (fro), IHC (p) - ABIN111178
Joplin, Strain, Neuberger: Immuno-isolation and culture of biliary epithelial cells from normal human liver. in In vitro cellular & developmental biology : journal of the Tissue Culture Association 1990
Show all 9 references for ABIN111178
Human Monoclonal EPCAM Primary Antibody for CyTOF, ELISA - ABIN153141
Jordinson, El-Hariry, Calnan, Calam, Pignatelli: Vicia faba agglutinin, the lectin present in broad beans, stimulates differentiation of undifferentiated colon cancer cells. in Gut 1999
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Human Monoclonal EPCAM Primary Antibody for FACS, IF - ABIN614761
Edwards, Grzyb, Dressler, Mansel, Zava, Sledge, McGuire: Monoclonal antibody identification and characterization of a Mr 43,000 membrane glycoprotein associated with human breast cancer. in Cancer research 1986
Show all 7 references for ABIN614761
Human Monoclonal EPCAM Primary Antibody for FACS, IHC (fro) - ABIN356311
Litvinov, Velders, Bakker, Fleuren, Warnaar: Ep-CAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule. in The Journal of cell biology 1994
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Human Monoclonal EPCAM Primary Antibody for EIA, WB - ABIN114701
Abe, Kuroki, Imakiire, Yamauchi, Yamada, Arakawa, Kuroki: Preparation of recombinant MK-1/Ep-CAM and establishment of an ELISA system for determining soluble MK-1/Ep-CAM levels in sera of cancer patients. in Journal of immunological methods 2002
Show all 3 references for ABIN114701
Human Monoclonal EPCAM Primary Antibody for IHC (p) - ABIN180642
Epenetos, Canti, Taylor-Papadimitriou, Curling, Bodmer: Use of two epithelium-specific monoclonal antibodies for diagnosis of malignancy in serous effusions. in Lancet 1982
Show all 2 references for ABIN180642
Mouse (Murine) Monoclonal EPCAM Primary Antibody for IHC (fro), IP - ABIN1042592
Farr, Nelson, Truex, Hosier: Epithelial heterogeneity in the murine thymus: a cell surface glycoprotein expressed by subcapsular and medullary epithelium. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1991
Human Monoclonal EPCAM Primary Antibody for IHC, ELISA - ABIN969099
Kimura, Kato, Faried, Sohda, Nakajima, Fukai, Miyazaki, Masuda, Fukuchi, Kuwano: Prognostic significance of EpCAM expression in human esophageal cancer. in International journal of oncology 2006
Human Polyclonal EPCAM Primary Antibody for IF (p), IHC (p) - ABIN687592
Ahn, Lee, Ko: Optimization of ELISA conditions to quantify colorectal cancer antigen-antibody complex protein (GA733-FcK) expressed in transgenic plant. in Monoclonal antibodies in immunodiagnosis and immunotherapy 2014
EpCAM acts as a partner of E-cadherin (show CDH1 Antibodies) to control adhesiveness and integrity as well as plasticity and morphogenesis within simple epithelia
identification of EpCAM in a gain-of-function screen for inducers of abnormal tissue mixing during gastrulation
that epithelial cell adhesion molecule showed different expression pattern among salivary gland neoplasms and in different grades of mucoepidermoid carcinomas
we concluded that the peptide could be a better supplement to the EpCAM antibody for capturing Circulating tumor cells (CTCs) in microfluidic system with broader spectrum
This study presented a molecular characterization of congenital tufting enteropathy Italian patients, and identified three mutations in the EpCAM gene
EpCAM serves as a potential biomarker of prognostic significance that could be used to identify oral squamous cell carcinoma patients at high risk and to predict patient survival
Findings show that the EGF (show EGF Antibodies)-like domain of EpCAM is cleaved off in cancer cells which have undergone epithelial-mesenchymal transition.
Based on these results, it can be concluded that EpCAM is suitable for use as an EC biomarker, therapeutic target, and effective parameter for tumor transfer and prognosis evaluation by aptamer SYL3C staining
CHD4 (show CHD4 Antibodies) was abundantly expressed in EpCAM(+) hepatocellular carcinoma with expression of hepatic stem cell markers and poor prognosis in two independent cohorts.
Flow cytometry assay showed doxorubicin exposure decreased EpCAM positive cell quantities in three HCC (show FAM126A Antibodies) cell lines. EpCAM siRNA knock-down attenuated cell mortality after doxorubicin exposure
EpCAM based capture detects and recovers circulating tumor cells from all subtypes of breast cancer except those low claudin expression.
Positive staining for CK19 (show KRT19 Antibodies) suggests a possible LPC (show PCSK7 Antibodies) origin of the EpCAM positive hepatocellular carcinoma .
Knock-down EpCAM cell model of congenital tufting enteropathy was developed. In vivo inducible mouse model was developed resulting in mutant EpCAM protein.
in addition to converting to cholangiocyte-like cells, Sox9 (show SOX9 Antibodies)(+)EpCAM(-) cells provide luminal space near expanded ductular structures to prevent deterioration of the injuries and potentially supply new hepatocytes to repair damaged tissues
EpCAM is a highly conserved protein present in fishes, amphibians, reptiles, birds, marsupials, and placental mammals, and is subject to shedding, gamma-secretase-dependent regulated intramembrane proteolysis, and proteasome-mediated degradation.
Suggest pivotal role of EpCAM in intestinal epithelial structure and integrity, with mutations resulting in congenital tufting enteropathy.
mTrop1/Epcam knockout mice develop congenital tufting enteropathy through dysregulation of intestinal E-cadherin (show CDH1 Antibodies)/beta-catenin (show CTNNB1 Antibodies).
EpCAM contributes to formation of intestinal barrier by recruiting claudins to cell-cell junctions.
These results conclusively link EpCAM expression to Langerhan cell (LC) motility/migration and LC migration to immune regulation.
Results show that SSCs are the most concentrated in CD9 (show CD9 Antibodies)(+)EPCAM(low/-) population and also suggest that EPCAM plays an important role in progenitor cell amplification in the mouse spermatogenic system.
EpCAM could contribute substantially to the pathogenesis of lung cancer.
EpCAM was required for differentiation or survival of parietal trophoblast giant cells, normal development of the placental labyrinth and establishment of a competent maternal-fetal circulation.
Ep-CAM may act as a physical homophilic interaction molecule between IELs and IECs at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection [Ep-CAM]
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
, tumor-associated calcium signal transducer
, epithelial cell adhesion molecule
, tumor-associated calcium signal transducer 1
, CD7 antigen (p41)
, T-cell antigen CD7
, T-cell leukemia antigen
, T-cell surface antigen Leu-9
, p41 protein
, adenocarcinoma-associated antigen
, cell surface glycoprotein Trop-1
, epithelial glycoprotein 314
, human epithelial glycoprotein-2
, major gastrointestinal tumor-associated protein GA733-2
, membrane component, chromosome 4, surface marker (35kD glycoprotein)
, Trop-1 protein
, lymphocyte antigen 74
, panepithelial glycoprotein 314
, protein 289A
, epithelial glycoprotein