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EPCAM encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. Additionally we are shipping EPCAM Proteins (44) and EPCAM Kits (43) and many more products for this protein.
Showing 10 out of 510 products:
Human Monoclonal EPCAM Primary Antibody for IHC (fro), IF - ABIN111179
Balzar, Winter, de Boer, Litvinov: The biology of the 17-1A antigen (Ep-CAM). in Journal of molecular medicine (Berlin, Germany) 2000
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Human Monoclonal EPCAM Primary Antibody for IHC (fro), IHC (p) - ABIN111178
Joplin, Strain, Neuberger: Immuno-isolation and culture of biliary epithelial cells from normal human liver. in In vitro cellular & developmental biology : journal of the Tissue Culture Association 1990
Show all 9 references for ABIN111178
Human Monoclonal EPCAM Primary Antibody for FACS, IF - ABIN614761
Edwards, Grzyb, Dressler, Mansel, Zava, Sledge, McGuire: Monoclonal antibody identification and characterization of a Mr 43,000 membrane glycoprotein associated with human breast cancer. in Cancer research 1986
Show all 7 references for ABIN614761
Human Monoclonal EPCAM Primary Antibody for FACS, IHC (fro) - ABIN356312
Litvinov, Velders, Bakker, Fleuren, Warnaar: Ep-CAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule. in The Journal of cell biology 1994
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Human Monoclonal EPCAM Primary Antibody for FACS, IHC (fro) - ABIN356311
Tsubura, Senzaki, Sasaki, Hilgers, Morii: Immunohistochemical demonstration of breast-derived and/or carcinoma-associated glycoproteins in normal skin appendages and their tumors. in Journal of cutaneous pathology 1992
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Human Monoclonal EPCAM Primary Antibody for EIA, WB - ABIN114701
Abe, Kuroki, Imakiire, Yamauchi, Yamada, Arakawa, Kuroki: Preparation of recombinant MK-1/Ep-CAM and establishment of an ELISA system for determining soluble MK-1/Ep-CAM levels in sera of cancer patients. in Journal of immunological methods 2002
Show all 3 references for ABIN114701
Human Monoclonal EPCAM Primary Antibody for IHC (p) - ABIN180642
Epenetos, Canti, Taylor-Papadimitriou, Curling, Bodmer: Use of two epithelium-specific monoclonal antibodies for diagnosis of malignancy in serous effusions. in Lancet 1982
Show all 2 references for ABIN180642
Human Polyclonal EPCAM Primary Antibody for IF (p), IHC (p) - ABIN687592
Ahn, Lee, Ko: Optimization of ELISA conditions to quantify colorectal cancer antigen-antibody complex protein (GA733-FcK) expressed in transgenic plant. in Monoclonal antibodies in immunodiagnosis and immunotherapy 2014
Human Monoclonal EPCAM Primary Antibody for IHC, ELISA - ABIN969099
Kimura, Kato, Faried, Sohda, Nakajima, Fukai, Miyazaki, Masuda, Fukuchi, Kuwano: Prognostic significance of EpCAM expression in human esophageal cancer. in International journal of oncology 2006
Mouse (Murine) Monoclonal EPCAM Primary Antibody for IHC (fro), IP - ABIN1042592
Farr, Nelson, Truex, Hosier: Epithelial heterogeneity in the murine thymus: a cell surface glycoprotein expressed by subcapsular and medullary epithelium. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1991
EpCAM acts as a partner of E-cadherin (show CDH1 Antibodies) to control adhesiveness and integrity as well as plasticity and morphogenesis within simple epithelia
identification of EpCAM in a gain-of-function screen for inducers of abnormal tissue mixing during gastrulation
We revealed a new molecular mechanism of MTA1 (show MTA1 Antibodies)-mediated invasion and metastasis in lung cancer through downstream target EpCAM, and interfering with EpCAM function may be a novel therapeutic strategy for treatment of MTA1 (show MTA1 Antibodies)-overexpressing lung carcinoma
Lower GA733-2 expression in cancer tissues appeared to correlate with lymph node metastases (P < 0.05). GA733-1 (show TACSTD2 Antibodies) gene expression was significantly higher in cancerous samples
knockdown of EpCAM can inhibition breast cancer cell growth and metastasis via inhibition of the Ras/Raf (show RAF1 Antibodies)/ERK (show EPHB2 Antibodies) signaling pathway and MMP-9 (show MMP9 Antibodies)
Results indicate that the anti-epithelial cell adhesion molecule (EpCAM) monoclonal antibodie can potentially be used for cancer-targeted therapy.
Hepatitis B virus X protein induces EpCAM expression via active DNA demethylation.
In this study, the authors developed a nanoparticle-mediated platform based on microfluidics to analyze the differential expressions of epithelial cell adhesion molecule (EpCAM) on CTCs in an animal model
TROP-1/Ep-CAM and CD24 (show CD24 Antibodies) may play key roles in the progression of ovarian cancer through promoting migration, proliferation, inhibiting cell apoptosis and adhesion, and disturbing cell cycle.
EpCAM can be used as a diagnostic biomarker for clinical detection of colorectal cancer.
A major role of CD24 (show CD24 Antibodies) and EpCAM for the preservation of self-renewal capacity in MCF-7 cells.
Results show that EpCAM overexpression in colorectal cancer cells is strongly associated with tumor progression, and may be regulated by epigenetic mechanisms.
Knock-down EpCAM cell model of congenital tufting enteropathy was developed. In vivo inducible mouse model was developed resulting in mutant EpCAM protein.
in addition to converting to cholangiocyte-like cells, Sox9 (show SOX9 Antibodies)(+)EpCAM(-) cells provide luminal space near expanded ductular structures to prevent deterioration of the injuries and potentially supply new hepatocytes to repair damaged tissues
EpCAM is a highly conserved protein present in fishes, amphibians, reptiles, birds, marsupials, and placental mammals, and is subject to shedding, gamma-secretase-dependent regulated intramembrane proteolysis, and proteasome-mediated degradation.
Suggest pivotal role of EpCAM in intestinal epithelial structure and integrity, with mutations resulting in congenital tufting enteropathy.
mTrop1/Epcam knockout mice develop congenital tufting enteropathy through dysregulation of intestinal E-cadherin (show CDH1 Antibodies)/beta-catenin (show CTNNB1 Antibodies).
EpCAM contributes to formation of intestinal barrier by recruiting claudins to cell-cell junctions.
These results conclusively link EpCAM expression to Langerhan cell (LC) motility/migration and LC migration to immune regulation.
Results show that SSCs are the most concentrated in CD9 (show CD9 Antibodies)(+)EPCAM(low/-) population and also suggest that EPCAM plays an important role in progenitor cell amplification in the mouse spermatogenic system.
EpCAM could contribute substantially to the pathogenesis of lung cancer.
EpCAM was required for differentiation or survival of parietal trophoblast giant cells, normal development of the placental labyrinth and establishment of a competent maternal-fetal circulation.
Ep-CAM may act as a physical homophilic interaction molecule between IELs and IECs at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection [Ep-CAM]
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
, tumor-associated calcium signal transducer
, epithelial cell adhesion molecule
, tumor-associated calcium signal transducer 1
, CD7 antigen (p41)
, T-cell antigen CD7
, T-cell leukemia antigen
, T-cell surface antigen Leu-9
, p41 protein
, adenocarcinoma-associated antigen
, cell surface glycoprotein Trop-1
, epithelial glycoprotein 314
, human epithelial glycoprotein-2
, major gastrointestinal tumor-associated protein GA733-2
, membrane component, chromosome 4, surface marker (35kD glycoprotein)
, Trop-1 protein
, lymphocyte antigen 74
, panepithelial glycoprotein 314
, protein 289A
, epithelial glycoprotein