anti-Ets Variant 6 (ETV6) Antibodies

ETV6 encodes an ETS family transcription factor. Additionally we are shipping ETV6 Proteins (5) and ETV6 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ETV6 2120 P41212
ETV6 312777  
ETV6 14011 P97360
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Top anti-ETV6 Antibodies at antibodies-online.com

Showing 10 out of 111 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-ETV6 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-ETV6 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from HeLa/HepG2/Jurkat cells, using ETV6 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using ETV6 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Chicken Rabbit Un-conjugated IC, IF, IP, IHC, WB Immunofluorescent analysis of TEL staining in Jurkat cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of TEL staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB 100 μL Log in to see 16 Days
$175.80
Details
Bat Rabbit Un-conjugated IHC, WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Bat Rabbit Un-conjugated IHC (p), WB Anti-ETV6 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958978 concentration 10 ug/ml. 50 μg Log in to see 7 to 9 Days
$676.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Mouse Rabbit Un-conjugated WB ETV6 Antibody (Center) (ABIN658417) western blot analysis in mouse lung tissue lysates (35 µg/lane). This demonstrates the ETV6 antibody detected the ETV6 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details

ETV6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus)


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Top referenced anti-ETV6 Antibodies

  1. Human Polyclonal ETV6 Primary Antibody for ICC, IF - ABIN4309682 : Noetzli, Lo, Lee-Sherick, Callaghan, Noris, Savoia, Rajpurkar, Jones, Gowan, Balduini, Pecci, Gnan, De Rocco, Doubek, Li, Lu, Leung, Landolt-Marticorena, Hunger, Heller, Gutierrez-Hartmann, Xiayuan et al.: Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia. ... in Nature genetics 2015 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal ETV6 Primary Antibody for IHC (p), ELISA - ABIN560810 : Meester-Smoor, Janssen, ter Haar, van Wely, Aarnoudse, van Oord, van Tilburg, Zwarthoff: The ETS family member TEL binds to nuclear receptors RAR and RXR and represses gene activation. in PLoS ONE 2011 (PubMed)
    Show all 2 Pubmed References

More Antibodies against ETV6 Interaction Partners

Zebrafish Ets Variant 6 (ETV6) interaction partners

  1. Dominant-negative truncated ETV6 with deletions of the ETS (show ETS1 Antibodies) domain or the PNT (show ETS2 Antibodies) domain interfered with repression by full-length ETV6 and affected expression of early hematopoietic and erythroid markers in embryos.

  2. the transcriptional repressor Tel plays an evolutionarily conserved role in angiogenesis: it is indispensable for the sprouting of human endothelial cells and for normal development of the Danio rerio blood circulatory system

Human Ets Variant 6 (ETV6) interaction partners

  1. Report ETV6-rearranged low-grade sinonasal adenocarcinomas.

  2. will also provide an overview of common clinical features as well as recommendations for patient screening and follow-up and will debate whether additional clinical features should be included with the germline ETV6 syndrome[review]

  3. The clinical significance of ETV6-RUNX1 (show RUNX1 Antibodies).

  4. Deliver the necessary promotional drive for the progression of ETV6-RUNX1 (show RUNX1 Antibodies)+ pre-leukaemic cells.

  5. Data suggest that, for ETV6 (which harbors only a single DNA contact interface for both specific and nonspecific interactions), intersegmental jumping represents a major molecular event that significantly modifies the thermodynamics and kinetics of DNA target search; site-specific DNA binding by ETV6 involves a kinetic intermediate at the cognate sequence.

  6. Our findings suggest ETV6-RUNX1 (show RUNX1 Antibodies) is associated with space-time clustering of childhood leukemia (CL) and are consistent with an infection interacting with that oncogene (show RAB1A Antibodies) in early life leading to clinical leukemia.

  7. EGFR (show EGFR Antibodies) activation leads to the induction of miR (show MLXIP Antibodies)-96 expression and suppression of ETV6, which contributes to prostate cancer progression.

  8. we demonstrate the expression of the ETV6-NTRK3 fusion (show NTRK3 Antibodies) oncogene (show RAB1A Antibodies) in a small subset of inflammatory myofibroblastic tumors

  9. ETV6-NTRK3 (show NTRK3 Antibodies) translocated papillary thyroid carcinomas are locoregionally aggressive and can metastasize distantly.

  10. We report 6 cases of secretory carcinomas of the skin harboring the ETV6-NTRK3 (show NTRK3 Antibodies) gene fusion

Mouse (Murine) Ets Variant 6 (ETV6) interaction partners

  1. Together with similar observations made in human PAX5 (show PAX5 Antibodies)-ETV6(+) B-ALLs, these data identified PAX5 (show PAX5 Antibodies)-ETV6 fusion as a potent oncoprotein that drives B-cell leukemia development.

  2. ETV6 DNA binding inhibition is established by the stability of its inhibitory helix

  3. Studied the combination of Etv6-RUNX1 (show RUNX1 Antibodies) and Pax5 (show PAX5 Antibodies)(+/-) alleles, they generated a transplantable B220 (show PTPRC Antibodies) + CD19 (show CD19 Antibodies)+ B-ALL with a significant disease incidence; RNA-seq analysis showed a gene expression pattern consistent with arrest at the pre-B stage.

  4. In murine models of B-cell progenitors, evidence found that ETV6- RUNX1 (show RUNX1 Antibodies) alters the expression of cytoskeletal regulatory genes, resulting in a block of the CDC42 (show CDC42 Antibodies) signaling pathway, and compromises the chemotactic response to CXCL12 (show CXCL12 Antibodies).

  5. ETV6-SAM (show TTN Antibodies) domain interface mutations block ETV6-NTRK3 (show NTRK3 Antibodies)-induced cellular transformation

  6. the autoinhibition of ETV6 DNA binding by sequences C-terminal to its ETS (show ETS1 Antibodies) domain

  7. find that both IRS1 (show IRS1 Antibodies) and kinase active IGF1R (show IGF1R Antibodies) are required for ETV6-NTRK3 (show NTRK3 Antibodies) transformation, that tyrosine phosphorylated IRS1 (show IRS1 Antibodies) is present in high molecular weight complexes with EN and IGF1R (show IGF1R Antibodies), and that EN colocalizes with IGF1R (show IGF1R Antibodies) at the plasma membrane

  8. Cytogenetic study of 33 children with ETV6-RUNX1 (show RUNX1 Antibodies) positive acute lymphoblastic leukemia predict long term survival.

  9. TEL binding to IRF-8 (show IRF8 Antibodies) for recruitment of HDAC3 (show HDAC3 Antibodies) is regulated by gamma-interferon (show IFNG Antibodies)

  10. the ability of TEL to repress transcription and suppress growth is regulated by sumoylation and nuclear export

ETV6 Antigen Profile

Protein Summary

This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

Gene names and symbols associated with anti-Ets Variant 6 (ETV6) Antibodies

  • ets variant gene 6 (TEL oncogene) (etv6) antibody
  • ets variant 6 (ETV6) antibody
  • ets variant 6 (etv6) antibody
  • ets variant 6 (LOC100352251) antibody
  • ets variant 6 (Etv6) antibody
  • ets variant gene 6 (TEL oncogene) (Etv6) antibody
  • ets variant gene 6 (TEL oncogene) (ETV6) antibody
  • AW123102 antibody
  • AW557856 antibody
  • etv-6 antibody
  • id:ibd2308 antibody
  • Tel antibody
  • TEL/ABL antibody

Protein level used designations for anti-Ets Variant 6 (ETV6) Antibodies

transcription factor ETV6 , ztel , ets variant gene 6 (TEL oncogene) , TEL oncogene , ets variant 6 , ETS translocation variant 6 , ETS-related protein Tel1 , TEL1 oncogene , translocation-ets-leukemia , ets domain protein

GENE ID SPECIES
114444 Danio rerio
473366 Pan troglodytes
486685 Canis lupus familiaris
549634 Xenopus (Silurana) tropicalis
100063341 Equus caballus
100352251 Oryctolagus cuniculus
2120 Homo sapiens
312777 Rattus norvegicus
504512 Bos taurus
14011 Mus musculus
395750 Gallus gallus
Selected quality suppliers for anti-ETV6 (ETV6) Antibodies
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