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The Fos gene family consists of 4 members FOSL1, and FOSL2. Additionally we are shipping FOSL1 Kits (18) and FOSL1 Proteins (10) and many more products for this protein.
Showing 10 out of 89 products:
Cow (Bovine) Polyclonal FOSL1 Primary Antibody for IHC, WB - ABIN2777265
Debinski, Gibo: Fos-related antigen 1 modulates malignant features of glioma cells. in Molecular cancer research : MCR 2005
Show all 3 Pubmed References
Human Polyclonal FOSL1 Primary Antibody for ELISA, WB - ABIN251492
Belguise, Kersual, Galtier, Chalbos: FRA-1 expression level regulates proliferation and invasiveness of breast cancer cells. in Oncogene 2005
Study shows that FOSL1 is the main immediate early AP-1 (show JUN Antibodies) member induced by melanoma oncogenes; found that FOSL1 is involved in melanoma cell migration as well as cell proliferation and anoikis-independent growth.
a Fra-1-miR (show MLXIP Antibodies)-134 axis drives a positive feedback loop that amplifies ERK (show EPHB2 Antibodies)/JNK (show MAPK8 Antibodies) signaling and reduces chemosensitivity in ovarian cancer cells.
PKCtheta (show PRKCQ Antibodies);-induced phosphorylations control the ability of Fra-1 to stimulate gene expression and breast cancer cell migration.
Multivariate analysis identified Fra-1 as an independent prognostic factor. Fra-1 may be involved in the progress of hepatocellular carcinoma and could be a promising molecular candidate in the diagnosis and treatment of hepatocellular carcinoma.
Up-regulation of Fra-1 appeared in retinal ganglion cells following light-induced retina damage.
HGF (show HGF Antibodies)-induced FRA1 activation is associated with the fibrosis-dependent development of Hepatocellular Carcinoma.
Our results demonstrate that Fra-1 is an important determinant of the metastatic potential of human colon cancer cells, and that the Fra-1 classifier can be used as a prognostic predictor in colon cancer patients.
Results suggest that Fra-1 is upregulated in lung cancer tissues and functions by affecting the P53 (show TP53 Antibodies) signaling pathway.
SIRT1 (show SIRT1 Antibodies) expression correlated positively with Fra-1 expression, metastasis and overall survival in patients with colorectal cancer
We identified and confirmed that Fra-1 affected the expression level of CTTN (show CTTN Antibodies) and EZR (show EZR Antibodies) in vitro through LC-MS/MS analyses and western blot technology.
NF-kappaB (show NFKB1 Antibodies) and c-Jun (show JUN Antibodies) coregulate lipopolysaccharide-induced Fra-1 transcription.
Upon stimulation with poly(I:C), malaria parasite-infected red blood cells (iRBCs), or vesicular stomatitis virus (VSV), FOSL1 "translocated" from the nucleus to the cytoplasm, where it inhibited the interactions between TNF receptor-associated factor 3 (TRAF3 (show TRAF3 Antibodies)), TIR domain-containing adapter inducing IFN-beta (show IFNB1 Antibodies) (TRIF (show RNF138 Antibodies)), and Tank-binding kinase 1 (TBK1 (show TBK1 Antibodies)) via impairing K63-linked polyubiquitination of TRAF3 (show TRAF3 Antibodies) and TRIF (show RNF138 Antibodies).
Adipose-derived stromal cells overexpressing Fra-1 effectively protect against osteoarthritis.
Overexpression of Fosl1, which encodes a component of the AP-1 (show JUN Antibodies) transcription factor complex, in osteoblasts significantly blocked malleal capillary narrowing.
Fra-1 gene expression is activated in response lipopolysaccharide induced lung-injury in mice.
Data suggest that expression of Fra1 (fos-related antigen 1) in preadipocytes is up-regulated by arachidonic acid (AA) during late stages of adipogenesis; however, in early stage of adipogenesis, AA inhibits adipogenesis via Fra1-dependent mechanism.
Fra-1 plays a key role in promoting chronic CS-induced lung macrophagic inflammation in vivo
we demonstrate that Fra1 negatively controls plasma cell differentiation by repressing Blimp1 (show PRDM1 Antibodies) expression.
observations suggest that MyoD (show MYOD1 Antibodies) and pRb (show PGR Antibodies) work together cooperatively at the level of the intronic enhancer of Fra-1 during terminal cell cycle arrest
findings, based on a definitive genetic mouse model provide fundamental insights into mammary duct maturation and homeostasis and reveal that Scrib (show SCRIB Antibodies) loss activates a MAPK (show MAPK1 Antibodies)/Fra1 pathway that alters mammary progenitor activity
The Fos gene family consists of 4 members FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
, fos-related antigen 1
, FOS-like antigen 1