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FOSL1 antibody (Middle Region)

FOSL1 Reactivity: Human, Rat, Mouse, Dog, Cow, Rabbit, Horse, Guinea Pig, Zebrafish (Danio rerio), Sheep WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777265
  • Target See all FOSL1 Antibodies
    FOSL1 (FOS-Like Antigen 1 (FOSL1))
    Binding Specificity
    • 15
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 41
    • 33
    • 27
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Dog, Cow, Rabbit, Horse, Guinea Pig, Zebrafish (Danio rerio), Sheep
    Host
    • 39
    • 2
    • 2
    Rabbit
    Clonality
    • 43
    Polyclonal
    Conjugate
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FOSL1 antibody is un-conjugated
    Application
    • 35
    • 13
    • 13
    • 13
    • 11
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    TDFLQAETDK LEDEKSGLQR EIEELQKQKE RLELVLEAHR PICKIPEGAK
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 85%, Zebrafish: 85%
    Characteristics
    This is a rabbit polyclonal antibody against FOSL1. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human FOSL1
    Top Product
    Discover our top product FOSL1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 271 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Seitz, Schürmann, Pfeilschifter, Frank, Sader: "Identification of the Fra-1 transcription factor in healing skin flaps transplants: a potential role as a negative regulator of VEGF release from keratinocytes." in: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, Vol. 40, Issue 4, pp. 379-86, (2012) (PubMed).

    Kashiwada, Cassel, Colgan, Rothman: "NFIL3/E4BP4 controls type 2 T helper cell cytokine expression." in: The EMBO journal, Vol. 30, Issue 10, pp. 2071-82, (2011) (PubMed).

  • Target
    FOSL1 (FOS-Like Antigen 1 (FOSL1))
    Alternative Name
    FOSL1 (FOSL1 Products)
    Synonyms
    FRA antibody, FRA1 antibody, fra-1 antibody, AW538199 antibody, Fra1 antibody, Fra-1 antibody, fosl1 antibody, sb:eu506 antibody, si:ch211-145o7.4 antibody, FOS like 1, AP-1 transcription factor subunit antibody, fos-like antigen 1 antibody, FOS-like antigen 1a antibody, FOSL1 antibody, Fosl1 antibody, fosl1a antibody
    Background
    The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
    Alias Symbols: FRA1, fra-1, FRA
    Protein Interaction Partner: NME7, CREB5, USF1, LDOC1, JUNB, MAFB, MAF, JUN, DDIT3, ATF2, CEBPG, CEBPE, CEBPA, ATF4, ATF3, PARVG, WFDC1, TAB2, ATXN1, MYC, KPNA1, PSMC3, EP300, CREBBP, TRIM24, UBC, HDAC1, CALCOCO1, ATF1, CREB1, SRF, ELK1,
    Protein Size: 271
    Molecular Weight
    29 kDa
    Gene ID
    8061
    NCBI Accession
    NM_005438, NP_005429
    UniProt
    P15407
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