Fas Apoptotic Inhibitory Molecule 2 Proteins (FAIM2)

may mediate development and maintenance of the nervous system [RGD, Feb 2006].. Additionally we are shipping FAIM2 Antibodies (62) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FAIM2 23017 Q9BWQ8
FAIM2 72393 Q8K097
Rat FAIM2 FAIM2 246274 O88407
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Top FAIM2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days

FAIM2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

Top referenced FAIM2 Proteins

  1. Human FAIM2 Protein expressed in Wheat germ - ABIN1353388 : Müller, Maurer, Reimers, Vogt, Bucan: TRIM21, a negative modulator of LFG in breast carcinoma MDA-MB-231 cells in vitro. in International journal of oncology 2015 (PubMed)

More Proteins for Fas Apoptotic Inhibitory Molecule 2 (FAIM2) Interaction Partners

Human Fas Apoptotic Inhibitory Molecule 2 (FAIM2) interaction partners

  1. FAIM2 expression is significantly downregulated in human masticatory mucosa during wound healing

  2. our research showed that lncRNA-SNHG7 promotes the proliferation, migration and invasion, and inhibits apoptosis of lung cancer cells by enhancing the FAIM2 expression, suggesting that lncRNA-SNHG7 as a key regulator of gene expression, may be a promising therapeutic strategy for the treatment of lung cancer

  3. The interaction of TRIM21 (show TRIM21 Proteins) and LFG was analyzed by co-immunoprecipitation. To examine changes in regulatory processes, western blot analyses, real-time PCR, activity of apoptotic process and flow cytometric analyses were carried out.

  4. There are significant differences in the associations of the FAIM2 promoter methylation with sedentary behaviour and physical activity between obese and lean children.

  5. Methylation levels of the FAIM2 promoter are significantly associated with obesity and are independently associated with dyslipidaemia and its components in Chinese children.

  6. Low KRT13 (show KRT13 Proteins) mRNA expression is associated with oral squamous cell carcinoma.

  7. These results suggest that the TMBIM family has comparable functions in the maintenance of intracellular Ca(2 (show CA2 Proteins)) homeostasis in a wide variety of tissues

  8. Results indicated that FAIM2 beta-isoform is strongly expressed in breast tumour tissues. Fas (show FAS Proteins) sensitivity was reduced in the MCF10A breast cells expressing the FAIM2 beta-isoform.

  9. This study highlighted the importance of two candidate genes, SH2B1 (show SH2B1 Proteins) and FAIM2, in the risk of overweight/obesity.

  10. A polymorphism in FAIM2 is associated with higher myocardial infarction risk in type-2 diabetes mellitus subjects.

Mouse (Murine) Fas Apoptotic Inhibitory Molecule 2 (FAIM2) interaction partners

  1. Increased degeneration of dopaminergic neurons was found in animals with Faim2 deficiency.

  2. MiR (show MLXIP Proteins)-3202 can promote EC apoptosis in hyperglycemic conditions, which demonstrated that EC apoptosis induced by high-glucose conditions partly depends on miR (show MLXIP Proteins)-3202 targeting FAIM2.

  3. LFG plays a role in protecting T cells from apoptosis during antiviral immune response.

  4. Data suggest Faim2/LFG (lifeguard protein) protects against FasL-/Fas ligand (show FASL Proteins)-induced apoptosis by down-regulating calcium release from endoplasmic reticulum in cortical neurons.

  5. In Faim2-deficient mice, there was increased hippocampal cell death during acute bacterial meningitis.

  6. Expression of Faim2 is triggered, at least in part, by Fas-receptor (show FAS Proteins) activation and subsequent ERK (show EPHB2 Proteins) signaling.

  7. mechanism of action of LFG as an inhibitor of the Fas (show FAS Proteins) pathway and evidence of the neuroprotective role of LFG in cerebellar granule neurons and Purkinje cells in an organotypic cerebellar culture system

  8. This study demonistrated that lack of Faim2 caused an increase in susceptibility to combined oxygen-glucose deprivation in primary neurons as well as in caspase (show CASP3 Proteins)-associated cell death, stroke volume, and neurological impairment after cerebral ischemia.

  9. LFG is an endogenous inhibitor of FasL (show FASL Proteins)-mediated neuronal death detected in lipid rafts microdomains, and it mediates the FasL (show FASL Proteins) resistance of CNS differentiated neurons

FAIM2 Protein Profile

Protein Summary

may mediate development and maintenance of the nervous system

Gene names and symbols associated with FAIM2

  • Fas apoptotic inhibitory molecule 2 (FAIM2)
  • Fas apoptotic inhibitory molecule 2 (faim2)
  • Fas apoptotic inhibitory molecule 2a (faim2a)
  • fas apoptotic inhibitory molecule 2 (CpipJ_CPIJ015441)
  • Fas apoptotic inhibitory molecule 2 (Faim2)
  • 2900002L20Rik protein
  • faim2 protein
  • Lfg protein
  • Lfg2 protein
  • MGC84041 protein
  • MGC146456 protein
  • NGP35 protein
  • NMP25 protein
  • Nmp35 protein
  • TMBIM2 protein
  • zgc:110143 protein

Protein level used designations for FAIM2

Fas apoptotic inhibitory molecule 2 , protein lifeguard 2 , fas apoptotic inhibitory molecule 2 , neuromembrane protein 35 , neural membrane protein 35 , transmembrane BAX inhibitor motif-containing protein 2 , lifeguard

451885 Pan troglodytes
100196331 Salmo salar
100173980 Pongo abelii
444588 Xenopus laevis
541391 Danio rerio
779810 Xenopus (Silurana) tropicalis
6049123 Culex quinquefasciatus
23017 Homo sapiens
72393 Mus musculus
246274 Rattus norvegicus
426899 Gallus gallus
477613 Canis lupus familiaris
509790 Bos taurus
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