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anti-Fibrinogen-Like 2 (FGL2) Antibodies

The protein encoded by FGL2 is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. Additionally we are shipping Fibrinogen-Like 2 Kits (43) and Fibrinogen-Like 2 Proteins (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FGL2 10875 Q14314
FGL2 84586  
FGL2 14190 P12804
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Top anti-Fibrinogen-Like 2 Antibodies at

Showing 10 out of 80 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-FGL2 Antibody Titration: 0.2-1 ug/mlPositive Control... WB Suggested Anti-FGL2  Antibody Titration: 0.2-1 µg/mL  Positive Cont... 100 μL Log in to see 2 to 3 Days
Human Mouse Un-conjugated IHC (p), IP, ELISA, WB Immunoperoxidase of monoclonal antibody to FGL2 on formalin-fixed para... FGL2 monoclonal antibody (M01), clone 6D9 Western Blot analysis of FGL... 100 μg Log in to see 9 Days
Human Mouse Un-conjugated IHC, WB Western Blot analysis of FGL2 expression in transfected 293T cell line... 0.1 mg Log in to see 8 to 11 Days
Human Rabbit Un-conjugated WB Western blot analysis of FGL2 expression in HeLa (A), Jurkat (B), HuT7... 200 μL Log in to see 9 Days
Human Mouse Un-conjugated IHC (p), WB 0.1 mg Log in to see 3 to 4 Days
Mouse Rabbit Un-conjugated IHC, ELISA, WB   0.1 mg Log in to see 2 to 6 Days
Human Mouse Un-conjugated WB FGL2 monoclonal antibody (M02), clone 5A10. Western Blot analysis of F... 0.1 mg Log in to see 8 to 11 Days
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
Rat Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded: rat kidney tissue labeled with A... 100 μL Log in to see 3 to 7 Days
Human Rabbit FITC FACS, ELISA, WB   200 μL Log in to see 8 to 10 Days

FGL2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
, , , , ,
Rat (Rattus) , ,
, , , , , , , , , , ,
Mouse (Murine) ,

Top referenced anti-Fibrinogen-Like 2 Antibodies

  1. Human Monoclonal FGL2 Primary Antibody for IHC (p), IP - ABIN564725 : OBrien, Morrison, Smith: Expression of prothrombin and protease activated receptors in human myometrium during pregnancy and labor. in Biology of reproduction 2007 (PubMed)
    Show all 11 references for ABIN564725

  2. Mouse (Murine) Polyclonal FGL2 Primary Antibody for IHC, ELISA - ABIN1586047 : Jia, Wang, Wang, Chen, Chen, Li, Long, Chen, Shu, Liu, Wang: TNF-α upregulates Fgl2 expression in rat myocardial ischemia/reperfusion injury. in Microcirculation (New York, N.Y. : 1994) 2013 (PubMed)

  3. Human Monoclonal FGL2 Primary Antibody for IHC (p), WB - ABIN2473615 : Shalev, Liu, Koscik, Bartczak, Javadi, Wong, Maknojia, He, Liu, Diao, Winter, Manuel, McCarthy, Cattral, Gommerman, Clark, Phillips, Gorczynski, Zhang, Downey, Grant, Cybulsky, Levy: Targeted deletion of fgl2 leads to impaired regulatory T cell activity and development of autoimmune glomerulonephritis. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)

More Antibodies against Fibrinogen-Like 2 Interaction Partners

Human Fibrinogen-Like 2 (FGL2) interaction partners

  1. these results suggest that FGL-2 mediates angiogenesis and tumorigenesis not by thrombin (show F2 Antibodies)-mediated mechanism but rather through FGF-2 (show FGF2 Antibodies)/ERK (show EPHB2 Antibodies) signaling pathway.

  2. Results show that FGL2 functions as a key immune-suppressive modulator and has potential as an immunotherapeutic target for treating glioblastoma multiforme (GBM).

  3. FGL-2 prothrombinase (show F10 Antibodies) activity in PBMC of lymphoma patients is increased in active disease and normalizes during remission, thus being a potential marker for follow up of lymphoma patients.

  4. Studied fibrinogen-like protein 2 expression and its role in CRC (show CALR Antibodies) metastasis and underlying molecular mechanisms; results suggest that FGL2 plays an important oncogenic role in CRC (show CALR Antibodies) aggressiveness by inducing EMT (show ITK Antibodies).

  5. The selected peptide sequence NPG (show OPA1 Antibodies)-12 may be a critical domain for hfgl2 prothrombinase (show F10 Antibodies) activity.

  6. The proliferation index of CD8 (show CD8A Antibodies)(+)T cells after blocking FGL2 was higher.

  7. immunomodulatory activity of FGL2 may be involved in the immunopathogenesis of inflammatory bowel disease

  8. Circulating fibrinogen-like protein 2 is increased in patients with systemic sclerosis.

  9. Serum fgl2 levels were increased among renal allograft recipients with acute rejection episodes to an extent dependent upon the pathological type and severity of the response.

  10. FGL2 contributes to hepatocellular carcinoma tumour growth and angiogenesis in a thrombin (show F2 Antibodies)-dependent manner, and downregulation of its expression might be of therapeutic significance in HCC (show FAM126A Antibodies).

Pig (Porcine) Fibrinogen-Like 2 (FGL2) interaction partners

  1. soluble FGL2 might be a potential renoprotective mediator involved in the renal self-repairing and remodeling.

  2. studies of pig-to-baboon kidney xenografts undergoing acute vascular rejection in vivo revealed induction of pfgl2 expression on graft vascular endothelial cells.

Mouse (Murine) Fibrinogen-Like 2 (FGL2) interaction partners

  1. FGL2 appears as one of the key players in immune regulatory processes favoring metacestode survival by promoting Regulatory T-cell activity and IL-17A (show IL17A Antibodies) production that contributes to FGL2-regulation.

  2. TNF-alpha (show TNF Antibodies), and FGL2 form an integral network that contributes to coagulation and complement activation, and suggest that those are potential therapeutic targets in viral FH intervention.

  3. these data strongly suggest that Treg cells expressing FGL2 mediate rapamycin-induced tolerance. Furthermore, a gene biomarker panel that includes fgl2 can distinguish between rejecting and tolerant grafts.

  4. Mouse susceptibility to MHV-3-induced fulminant hepatitis may rely on C5a/C5aR interactions, for which ERK1/2 (show MAPK1/3 Antibodies) and p38 (show CRK Antibodies) pathways participate in up-regulating Fgl2 expression.

  5. Targeted deletion of FGL2 leads to increased early viral replication and enhanced adaptive immunity in a murine model of acute viral hepatitis.

  6. Cysteines at positions 94, 97, 184 and 187, found in the coiled-coil domain were shown to be crucial for FGL2 oligomerization.

  7. FGL2 binding to the FcgammaRIIB receptor expressed on sinusoidal endothelial cells (SECs) is a critical event in the initiation of the hepatic reperfusion injury cascade through induction of SEC and hepatocyte death.

  8. The prothrombinase activity of FGL2 contributes to the pathogenesis of experimental arthritis.

  9. Fgl2 cleaves prothrombin (show F2 Antibodies) to thrombin (show F2 Antibodies) consistent with serine protease (show F2 Antibodies) activity and requires calcium, phospholipids, and factor Va for its full activity.

  10. While membrane-bound Fgl2 acts as a prothrombinase, soluble Fgl2 is an immunomodulatory protein that has the ability to modulate T cell responses and to alter dendritic cell (DC) maturation to favor production of tolerogenic DC.

Fibrinogen-Like 2 (FGL2) Antigen Profile

Protein Summary

The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites.

Gene names and symbols associated with FGL2

  • fibrinogen-like 2 (FGL2) antibody
  • fibrinogen-like 2 (fgl2) antibody
  • fibrinogen-like 2 (LOC100228349) antibody
  • fibrinogen-like 2 (LOC100351573) antibody
  • fibrinogen-like 2 (Fgl2) antibody
  • fibrinogen-like protein 2 (Fgl2) antibody
  • AI385601 antibody
  • FGL2 antibody
  • fibroleukin antibody
  • musfiblp antibody
  • pT49 antibody
  • si:ch211-276e22.3 antibody
  • T49 antibody
  • wu:fj83c10 antibody
  • zgc:136619 antibody

Protein level used designations for FGL2

fibrinogen-like 2 , fibroleukin , fibroleukin-like , fibrinogen-like protein 2 , associated with MHV-3 induced prothrombinase activity , cytotoxic T-lymphocyte-specific protein , prothrombinase

475902 Canis lupus familiaris
495355 Xenopus laevis
565637 Danio rerio
694856 Macaca mulatta
768821 Gallus gallus
100228349 Taeniopygia guttata
100351573 Oryctolagus cuniculus
100393441 Callithrix jacchus
100439476 Pongo abelii
100608696 Pan troglodytes
100619845 Monodelphis domestica
10875 Homo sapiens
84586 Rattus norvegicus
448808 Sus scrofa
511711 Bos taurus
14190 Mus musculus
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