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FGL2 antibody (AA 24-123)

FGL2 Reactivity: Human WB, ELISA, IP, IHC (p) Host: Mouse Monoclonal 6D9 unconjugated
Catalog No. ABIN564725
  • Target See all FGL2 Antibodies
    FGL2 (Fibrinogen-Like 2 (FGL2))
    Binding Specificity
    • 16
    • 11
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-123
    Reactivity
    • 44
    • 37
    • 25
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 60
    • 5
    Mouse
    Clonality
    • 61
    • 4
    Monoclonal
    Conjugate
    • 30
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FGL2 antibody is un-conjugated
    Application
    • 53
    • 27
    • 23
    • 13
    • 13
    • 11
    • 6
    • 4
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant FGL2.
    Sequence
    NNETEEIKDE RAKDVCPVRL ESRGKCEEAG ECPYQVSLPP LTIQLPKQFS RIEEVFKEVQ NLKEIVNSLK KSCQDCKLQA DDNGDPGRNG LLLPSTGAPG
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    FGL2 (NP_006673, 24 a.a. ~ 123 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    6D9
    Isotype
    IgG2a
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Long, You, Li, Jin, Huang, Li, Liu, Wang: "Sodium tanshinone IIA sulfonate ameliorates experimental coronary no-reflow phenomenon through down-regulation of FGL2." in: Life sciences, Vol. 142, pp. 8-18, (2015) (PubMed).

    Dong, Ye, Chen, Chen, Xie, Li, Lin, Huang: "Intestinal and peripheral fibrinogen-like protein 2 expression in inflammatory bowel disease." in: Digestive diseases and sciences, Vol. 59, Issue 4, pp. 769-77, (2014) (PubMed).

    Li, Wang, Long, Su, Bukhory, Dai, Jin, Huang, Jia, Li, Fan, Liu, Wang: "Novel antibody against a glutamic acid-rich human fibrinogen-like protein 2-derived peptide near Ser91 inhibits hfgl2 prothrombinase activity." in: PLoS ONE, Vol. 9, Issue 4, pp. e94551, (2014) (PubMed).

    Sun, Xi, Ding, Wang, Zhou, Ning: "Soluble FGL2, a novel effector molecule of activated hepatic stellate cells, regulates T-cell function in cirrhotic patients with hepatocellular carcinoma." in: Hepatology international, Vol. 8, Issue 4, pp. 567-575, (2014) (PubMed).

    Xu, Chen, Yang, Li, Zheng, Wu: "C5a/C5aR pathway is essential for the pathogenesis of murine viral fulminant hepatitis by way of potentiating Fgl2/fibroleukin expression." in: Hepatology (Baltimore, Md.), Vol. 60, Issue 1, pp. 114-24, (2014) (PubMed).

    Xi, Wang, Ye, Luo, Ning: "Combined adenovirus-mediated artificial microRNAs targeting mfgl2, mFas, and mTNFR1 protect against fulminant hepatic failure in mice." in: PLoS ONE, Vol. 8, Issue 11, pp. e82330, (2013) (PubMed).

    Ye, Huai, Chen, Ding, Chen, Cai: "Correlation of fibrinogen-like protein 2 with disease progression in patients with severe acute pancreatitis." in: Experimental and therapeutic medicine, Vol. 7, Issue 1, pp. 85-89, (2013) (PubMed).

    Selzner, Liu, Boehnert, Adeyi, Shalev, Bartczak, Xue-Zhong, Manuel, Rotstein, McGilvray, Grant, Phillips, Levy, Selzner: "FGL2/fibroleukin mediates hepatic reperfusion injury by induction of sinusoidal endothelial cell and hepatocyte apoptosis in mice." in: Journal of hepatology, Vol. 56, Issue 1, pp. 153-9, (2011) (PubMed).

    Liu, Xu, Xiao, Xiong, Wang, Gao, Yan, Ning: "The FGL2/fibroleukin prothrombinase is involved in alveolar macrophage activation in COPD through the MAPK pathway." in: Biochemical and biophysical research communications, Vol. 396, Issue 2, pp. 555-61, (2010) (PubMed).

    OBrien, Morrison, Smith: "Expression of prothrombin and protease activated receptors in human myometrium during pregnancy and labor." in: Biology of reproduction, Vol. 78, Issue 1, pp. 20-6, (2007) (PubMed).

    Shalev, Liu, Koscik, Bartczak, Javadi, Wong, Maknojia, He, Liu, Diao, Winter, Manuel, McCarthy, Cattral, Gommerman, Clark, Phillips, Gorczynski, Zhang, Downey, Grant, Cybulsky, Levy: "Targeted deletion of fgl2 leads to impaired regulatory T cell activity and development of autoimmune glomerulonephritis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 1, pp. 249-60, (2007) (PubMed).

  • Target
    FGL2 (Fibrinogen-Like 2 (FGL2))
    Alternative Name
    FGL2 (FGL2 Products)
    Synonyms
    FGL2 antibody, wu:fj83c10 antibody, zgc:136619 antibody, si:ch211-276e22.3 antibody, fibroleukin antibody, T49 antibody, pT49 antibody, AI385601 antibody, musfiblp antibody, fibrinogen like 2 antibody, fibrinogen like 2 L homeolog antibody, fibrinogen-like 2a antibody, fibrinogen-like 2 antibody, fibrinogen-like protein 2 antibody, FGL2 antibody, fgl2.L antibody, fgl2a antibody, Fgl2 antibody
    Background
    Full Gene Name: fibrinogen-like 2
    Synonyms: T49,pT49
    Gene ID
    10875
    NCBI Accession
    NM_006682
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