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anti-Fibroblast Activation Protein (FAP) Antibodies

FAP belongs to the serine protease family.

list all antibodies Gene Name GeneID UniProt
FAP 14089 P97321
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Top anti-Fibroblast Activation Protein Antibodies at

Showing 4 out of 6 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated ELISA, WB Western blot using affinity purified anti-FAP antibody shows detection... 25 μL Log in to see 2 to 3 Days
Mouse Rabbit Un-conjugated ELISA, WB Western blot using affinity purified anti-FAP antibody shows detection... 100 μg Log in to see 2 to 3 Days
Human Mouse Un-conjugated FACS, IP, IHC   100 μg Log in to see 11 to 16 Days
Mouse Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 11 to 16 Days

FAP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


More Antibodies against Fibroblast Activation Protein Interaction Partners

Mouse (Murine) Fibroblast Activation Protein (FAP) interaction partners

  1. In two different models of pulmonary fibrosis, intratracheal bleomycin instillation and thoracic irradiation, the study finds increased mortality and increased lung fibrosis in FAP-deficient mice compared with wild-type mice.

  2. Mouse FGF-21 (show FGF21 Antibodies), however, lacks the FAP cleavage site and is not cleaved by FAP.

  3. Data indicate that indolamine-2,3-dioxygenase (IDO (show IDO1 Antibodies)) and Fibroblast activation protein alpha (FAPalpha) were detectable in B16 melanoma tumor-bearing mice.

  4. A transgenic mouse model for pulmonary fibrosis was generated. After bleomycin induction, luciferase cDNA under the control of the FAPa promoter presents strong luminescence in the lungs especially; the expression level reflects the degree of the disease.

  5. The FAP(+) stromal cell may have roles in two adverse consequences of cancer.

  6. In NIH 3T3 cells overexpressing recombinant mouse FAP, FAP enzymatic activity during matrix production is important for the topographical organization of the ECM (show MMRN1 Antibodies) fibers.

  7. Authors conclude that the proteolytic activity of FAP participates in matrix degradation, but other functions of the protein stimulate increased tumor growth.

  8. FAP may be a potentially useful marker for wound age determination.

  9. Results suggest that FAP, a product preferentially expressed by TAF, could function as an effective tumor rejection antigen.

  10. FAP depletion inhibits tumor cell proliferation indirectly, increases accumulation of collagen, decreases myofibroblast content, and decreases blood vessel density in tumors.

Fibroblast Activation Protein (FAP) Antigen Profile

Protein Summary

This gene belongs to the serine protease family. The encoded protein is an inducible cell-surface bound glycoprotein specifically expressed in tumor-associated fibroblasts and pericytes of epithelial tumors and has protease and gelatinase activity. The protein plays a role in remodeling of the extracellular matrix (ECM) and may affect tumorigenesis and tissue repair. Alternately spliced transcript variants of this gene are described in the literature (PMID 9139873), but the full-length sequence of these variants is not available.

Gene names and symbols associated with FAP

  • fibroblast activation protein (Fap) antibody

Protein level used designations for FAP

fibroblast activation protein alpha , integral membrane serine protease , seprase

14089 Mus musculus
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