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Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression.. Additionally we are shipping FGF15 Antibodies (9) and FGF15 Proteins (6) and many more products for this protein.
Showing 3 out of 18 products:
Mouse (Murine) FGF15 ELISA Kit for Competition ELISA - ABIN481717
Assini, Mulvihill, Burke, Sutherland, Telford, Chhoker, Sawyez, Drangova, Adams, Kharitonenkov, Pin, Huff: Naringenin prevents obesity, hepatic steatosis, and glucose intolerance in male mice independent of fibroblast growth factor 21. in Endocrinology 2015
Show all 2 Pubmed References
Fgf15 is the sonic hedgehog (show SHH ELISA Kits) downstream signal to control thalamic regionalization, neurogenesis, and neuronal differentiation by regulating the expression and mutual segregation of neurogenic and proneural regulatory genes.
human microbiota was able to reduce the levels of tauro-beta-muricholic acid and induce expression of FXR (show NR1H4 ELISA Kits) target genes Fgf15 and Shp (show LAMC1 ELISA Kits) in ileum after long-term colonization. We show that a human microbiota can change BA composition and induce FXR (show NR1H4 ELISA Kits) signaling in colonized mice, but the levels of secondary BAs produced are lower than in mice colonized with a mouse microbiota
This study demonstrates that the FGF19 (show FGF19 ELISA Kits)-SHP (show LAMC1 ELISA Kits)-LSD1 (show KDM1A ELISA Kits) axis maintains homeostasis by suppressing unnecessary autophagic breakdown of cellular components, including lipids, under nutrient-rich postprandial conditions.
The elevation in circulating levels of adiponectin and Fgf15 led to normalized hepatic and serum levels of bile acids, limited hepatic accumulation of toxic bile, attenuated inflammation, and amelioration of liver injury in the ethanol-fed mNT knockout mice.
This study reveals SHP (show LAMC1 ELISA Kits) as a global transcriptional partner of SREBP-2 (show SREBF2 ELISA Kits) in regulation of sterol biosynthetic gene networks and provides a potential mechanism for cholesterol-lowering action of FGF19 (show FGF19 ELISA Kits).
Protective effects of farnesoid X receptor on hepatic lipid accumulation are mediated by hepatic FXR (show NR1H4 ELISA Kits) and are independent of intestinal FGF15 signaling.
Intestinal PPARalpha (show PPARA ELISA Kits)-UDP- Glucuronyltransferases and downstream FXR (show NR1H4 ELISA Kits)-FGF15 signalling play vital roles in control of bile acid homeostasis and the pathological development of colitis.
a direct role of intestinal FGF15/19 in the regulation of SI P450 (show POR ELISA Kits) expression and may have profound implications for the prediction of drug exposure in patients with compromised hepatic P450 (show POR ELISA Kits) function
findings implicate the brain in the antidiabetic action of systemic FGF19 (show FGF19 ELISA Kits) and establish the brain's capacity to rapidly, potently, and selectively increase insulin (show INS ELISA Kits)-independent glucose disposal
Ileal Fibroblast Growth Factor-15 (FGF15) expression was significantly reduced in Asbt (show SLC10A2 ELISA Kits)(-/-)apoE (show APOE ELISA Kits)(-/-) mice and was inversely correlated with expression of hepatic cholesterol 7-hydroxylase (Cyp7a1 (show CYP7A1 ELISA Kits)).
Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression.
, fibroblast growth factor 15