Filamin C, gamma Proteins (FLNC)

FLNC encodes one of three related filamin genes, specifically gamma filamin. Additionally we are shipping FLNC Antibodies (40) and FLNC Kits (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse FLNC FLNC 68794 Q8VHX6
Rat FLNC FLNC 362332  
FLNC 2318 Q14315
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Top FLNC Proteins at

Showing 3 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 15 to 18 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days

FLNC Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for Filamin C, gamma (FLNC) Interaction Partners

Mouse (Murine) Filamin C, gamma (FLNC) interaction partners

  1. HSPB7 (show HSPB7 Proteins) is essential for maintaining muscle integrity, which is achieved through its interaction with FLNC

  2. The data of this study presented here provide further support that FLNC, a muscle-specific protein (show TXLNB Proteins), could be a potential novel player in FTD (show FTL Proteins) pathogenesis.

  3. Aciculin interacts with filamin C and Xin and is essential for myofibril assembly.

  4. KY, IGFN1 and FLNC are part of a Z-band associated protein complex likely to provide structural support to the skeletal muscle sarcomere.

  5. filamin C may function in signal transduction or cellular migration of the myogenic progenitor cell population

  6. These data provide the first evidence that FLNc has a crucial role in muscle development and maintenance of muscle structural integrity and suggest the presence of a TRIO (show TRIO Proteins)-FLNc-dependent pathway in maintaining proper myotube structure.

  7. MuRF3 (show TRIM54 Proteins) has an essential role in maintaining cardiac integrity and function after acute myocardial infarction and turnover of FHL2 (show FHL2 Proteins) and gamma-filamin contributes to this cardioprotective function of MuRF3 (show TRIM54 Proteins)

  8. Cbl (show CBL Proteins)-associated protein provides another link between the myofibril cytoskeleton and the plasma membrane of muscle cells, and it may play a dynamic role in the regulation and maintenance of muscle structural integrity

Human Filamin C, gamma (FLNC) interaction partners

  1. This study therefore identifies both BAG3 (show BAG3 Proteins) reduction and autophagy promotion as potential therapies for FLNC(W2710X) myofibrillar myopathy, and identifies protein insufficiency due to sequestration, compounded by impaired autophagy, as the cause.

  2. Biallelic variants in FLNC can cause congenital dilated cardiomyopathy.

  3. Truncating mutations in FLNC caused an overlapping phenotype of dilated and left-dominant arrhythmogenic cardiomyopathies complicated by frequent premature sudden death

  4. a compelling evidence of the involvement of FLNC in the development of Hypertrophic Cardiomyopathy . Most of the FLNC variants were associated with mild forms ofHypertrophic Cardiomyopathy and a reduced penetrance

  5. FLNC is a disease gene for autosomal-dominant Restrictive Cardiomyopathy and broadens the phenotype spectrum of filaminopathies.

  6. The identification of Filamin C as a novel KCNE2 (show KCNE2 Proteins) ligand not only enhances current understanding of ion channel function and regulation, but also provides valuable information about possible pathways likely to be involved in long-QT syndrome pathogenesis

  7. Findings indicate a functional role of filamin C in cancers.

  8. Mutations in the gene encoding the sarcomeric protein filamin C cause a new form of familial hypertrophic cardiomyopathy.

  9. Aciculin interacts with filamin C and Xin and is essential for myofibril assembly.

  10. alpha2C-adrenoreceptor interaction with filamin-2

FLNC Protein Profile

Protein Summary

This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with Filamin C, gamma Proteins (FLNC)

  • filamin C, gamma (FLNC)
  • filamin C, gamma (flnc)
  • filamin C, gamma (Flnc)
  • 1110055E19Rik protein
  • ABP-280 protein
  • ABP280A protein
  • ABPA protein
  • ABPL protein
  • FLN2 protein
  • MFM5 protein
  • MPD4 protein

Protein level used designations for Filamin C, gamma Proteins (FLNC)

filamin C, gamma (actin binding protein 280) , gamma filamin , filamin C, gamma , filamin-C-like , ABP-280-like protein , ABP-L , FLN-C , actin binding protein 280 , actin-binding protein 280 , actin-binding-like protein , filamin, gamma , filamin-2 , filamin-C , gamma-filamin , ABP-L, gamma filamin , filamin 2 , 260kDa actin-binding protein , cgABP260 actin-binding domain

463711 Pan troglodytes
734178 Xenopus laevis
100329116 Xenopus (Silurana) tropicalis
100475857 Ailuropoda melanoleuca
68794 Mus musculus
362332 Rattus norvegicus
2318 Homo sapiens
100730013 Cavia porcellus
100518997 Sus scrofa
482266 Canis lupus familiaris
528415 Bos taurus
395260 Gallus gallus
101104655 Ovis aries
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