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Fragile X Mental Retardation 1 (FMR1) ELISA Kits

The protein encoded by FMR1 binds RNA and is associated with polysomes. Additionally we are shipping FMR1 Antibodies (157) and FMR1 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FMR1 2332 Q06787
Anti-Rat FMR1 FMR1 24948 Q80WE1
Anti-Mouse FMR1 FMR1 14265  
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Top FMR1 ELISA Kits at

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.105 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days

More ELISA Kits for FMR1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Fragile X Mental Retardation 1 (FMR1) interaction partners

  1. results support a model whereby dFMRP can modulate the neurotoxicity caused by TDP-43 (show TARDBP ELISA Kits) overexpression

  2. demonstrate that Zfrp8 genetically interacts with Fmr1 and tral (show LSM14A ELISA Kits) in an antagonistic manner. Zfrp8 and FMRP both control heterochromatin packaging, also in opposite ways

  3. dFmr1 protein is essential for proper cardiac function and establish the fly as a new model for studying the role(s) of FraX proteins in the heart.

  4. Driving expression of FMRpolyG enhanced induction of UPS impairment in cell models, while prevention of RAN translation attenuated UPS impairment in cells and suppressed the genetic interaction with UPS manipulation in Dr (show USP14 ELISA Kits)osophila

  5. These results show that dfmr1 acts in a neuron type-specific activity-dependent manner for sculpting dendritic arbors during early-use, critical period development of learning and memory circuitry in the Drosophila brain.

  6. upon the stimulation of replication stress, dFMR1 is associated with chromatin in a domain-specific manner, which is essential for its ability to induce the phosphorylation of H2Av (show H2AFV ELISA Kits).

  7. FMRP inhibits translation by binding directly to the L5 protein on the 80S ribosome.

  8. FMRP negatively regulates HSPG (show SDC2 ELISA Kits) co-receptors controlling trans-synaptic signaling during synaptogenesis

  9. FMRP and Ataxin-2 (show ATXN2 ELISA Kits) have roles in long-term olfactory habituation and neuronal translational control

  10. Dfmr1 mutants are less active than wild-type flies and interact with each other less often. Results raise the possibility of defective social expression with preserved receptive abilities.

Human Fragile X Mental Retardation 1 (FMR1) interaction partners

  1. PCR-P analysis of parents of female patients may discard or emphasize the suspicion of Fragile X Syndrome . If parents are normal for the mutation in the FMR1 gene, the patient can be concluded to be normal.

  2. Identified a tripartite correlation between schizophrenia, miR (show MLXIP ELISA Kits)-9-5p, and FMR1/FXR1 (show FXR1 ELISA Kits): functional overlaps and differences between FMR1 and its homologues could potentially shed light on both the function of miR (show MLXIP ELISA Kits)-9-5p and the etiology of schizophrenia.

  3. The correlation of ovarian reserve and serum anti-Mullerian hormone (show AMH ELISA Kits) levels and FMR1 CGG repeat number in women with <55 CGG repeats

  4. Advancing age, male sex, and lower X activation of the normal FMR1 allele in women carriers were significant in predicting worse postural balance

  5. found no evidence for a pathological increase in GSK3beta protein levels upon cellular loss of fragile x mental retardation protein

  6. Silencing of the fragile X mental retardation gene results in Autism spectrum disorder.

  7. An accumulation of 8 SNPs in the fragile gene family (FMR1, FXR1 (show FXR1 ELISA Kits) and FXR2 (show FXR2 ELISA Kits))were found associated with autistic traits in a sample of male patients.

  8. these data suggest that RAN translation of FMRpolyG ( FMR1)at CGG repeats triggers induction of UPS impairment and alterations in neuronal proteostasis that contribute to pathogenesis in Fragile X-associated tremor ataxia (show USP14 ELISA Kits) syndrome.

  9. Results suggest the genetic variation associated with FMR1 affects white matter microstructure independently of overall IQ.

  10. transcriptional silencing in fragile X syndrome via DNA methylation (show HELLS ELISA Kits) and hydroxymethylation

Zebrafish Fragile X Mental Retardation 1 (FMR1) interaction partners

  1. We identified thousands of clustered RNA editing sites in the zebrafish transcriptome and showed that Fmrp biochemically interacts with the Adar2a protein. The expression levels of the adar (show ADAR ELISA Kits) genes and Adar2 (show ADARB1 ELISA Kits) protein increased in fmr1-/- zebrafish

  2. Loss-of-function fmr1 mutants carrying an anti-fmr1 miRNA transgene show abnormal neuronal morphology and connectivity similar to that seen in human fragile X syndrome.

Mouse (Murine) Fragile X Mental Retardation 1 (FMR1) interaction partners

  1. the absence of fragile X mental retardation protein has divergent effects on the function of individual types of ion channels not only between brain regions

  2. Results of our study suggest that the eIF4E (show EIF4E ELISA Kits)/Fmr1 double mutant mouse may be a reliable model to study cognitive dysfunction in the context of autism spectrum disorder.

  3. The present demonstration of FMRP and key regulatory targets in the lens identifies a potential for the lens to provide a new research venue.

  4. examine the status of astrocytes and microglia in the cerebellum of Fmr1 mice during development and in adulthood

  5. Dysregulation of fragile X mental retardation protein-metabotropic glutamate receptor 5 (show GRM5 ELISA Kits) signaling pathway, accompanied with a downregulation of GABA(A) receptor beta3 subunit expression, may contribute to the 'autistic-like' features knockout mice.

  6. found no evidence for a pathological increase in GSK3beta protein levels upon cellular loss of FMRP, in contrast to what was found in the brain of Fmr1 knockout mice

  7. Overexpressing TRF2 (show TERF2 ELISA Kits)-S and silencing FMRP promotes mRNA entry to axons and enhances axonal outgrowth and neurotransmitter release from presynaptic terminals.

  8. fmr1 knock-out mice have deficits in motor learning-induced changes in dendritic spine turnover and new dendritic spine clustering, but not the motor learning-induced long-term stabilization of new dendritic spines.

  9. Fmr1 knockout mice had reduced synaptic vesicle unloading of hippocampal neurons and increased vesicle unloading in cerebellar neurons. FMRP plays a role in presynaptic functions.

  10. Findings unveil important roles for FMRP, FXR2P (show FXR2 ELISA Kits) and GluA1 (show GRIA1 ELISA Kits) in neuronal development, uncover a regulatory mechanism of GluA1 (show GRIA1 ELISA Kits), and reveal a functional convergence between fragile X proteins in neuronal development.

FMR1 Antigen Profile

Antigen Summary

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Gene names and symbols associated with FMR1

  • CG6203 gene product from transcript CG6203-RC (Fmr1) antibody
  • fragile X mental retardation 1 (FMR1) antibody
  • fragile X mental retardation 1 (Fmr1) antibody
  • fragile X mental retardation 1 (fmr1) antibody
  • fragile X mental retardation syndrome 1 (Fmr1) antibody
  • AT24755 antibody
  • BcDNA:GM08679 antibody
  • cg6203 antibody
  • dfmr antibody
  • dfmr1 antibody
  • dFmrp antibody
  • dfxr antibody
  • dfxr1 antibody
  • dFXRP antibody
  • Dmel\\CG6203 antibody
  • dmfr1 antibody
  • EP(3)3517 antibody
  • fmr antibody
  • Fmr-1 antibody
  • fmr1 antibody
  • Fmrp antibody
  • FRAXA antibody
  • FXR antibody
  • POF antibody
  • POF1 antibody
  • zFMR1 antibody

Protein level used designations for FMR1

CG6203-PA , CG6203-PB , CG6203-PC , CG6203-PD , CG6203-PE , CG6203-PF , CG6203-PG , CG6203-PH , CG6203-PI , Fmr1-PA , Fmr1-PB , Fmr1-PC , Fmr1-PD , Fmr1-PE , Fmr1-PF , Fmr1-PG , Fmr1-PH , Fmr1-PI , Fragile-X mental retardation protein , Fragile-X-related , dFmr1 , drosophila fragile X mental retardation protein , fragile X , fragile X mental retardation , fragile X mental retardation 1 , fragile X mental retardation gene , fragile X mental retardation protein , fragile X protein , fragile X related protein , fragile X-related , fragile x related , fragile-X , fragile X mental retardation protein 1 , fragile X mental retardation protein 1 homolog , fragile X mental retardation syndrome 1 homolog , fragile X mental retardation-1 protein , protein FMR-1 , ragile X mental retardation protein , fragile X mental retardation 1 protein , FMRP , mFmr1p

37528 Drosophila melanogaster
465894 Pan troglodytes
2332 Homo sapiens
481070 Canis lupus familiaris
24948 Rattus norvegicus
259191 Danio rerio
422395 Gallus gallus
100155078 Sus scrofa
507482 Bos taurus
100172902 Pongo abelii
14265 Mus musculus
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