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Fragile X Mental Retardation 1 (FMR1) ELISA Kits

The protein encoded by FMR1 binds RNA and is associated with polysomes. Additionally we are shipping FMR1 Antibodies (174) and FMR1 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
FMR1 2332 Q06787
Anti-Rat FMR1 FMR1 24948 Q80WE1
Anti-Mouse FMR1 FMR1 14265  
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Top FMR1 ELISA Kits at antibodies-online.com

Showing 1 out of 5 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 11 to 13 Days
$910.56
Details

More ELISA Kits for FMR1 Interaction Partners

Fruit Fly (Drosophila melanogaster) Fragile X Mental Retardation 1 (FMR1) interaction partners

  1. dFMRP cooperates with Piwi in maintaining genome integrity by silencing heterochromatic genes and suppressing transposon expression.

  2. results show Fragile X Mental Retardation Protein (FMRP) shapes neuron class-specific calcium signaling in excitatory vs. inhibitory neurons in developing learning/memory circuitry, and that FMRP mediates activity-dependent regulation of calcium signaling specifically during the early-use critical period.

  3. results support a model whereby dFMRP can modulate the neurotoxicity caused by TDP-43 (show TARDBP ELISA Kits) overexpression

  4. demonstrate that Zfrp8 genetically interacts with Fmr1 and tral (show LSM14A ELISA Kits) in an antagonistic manner. Zfrp8 and FMRP both control heterochromatin packaging, also in opposite ways

  5. dFmr1 protein is essential for proper cardiac function and establish the fly as a new model for studying the role(s) of FraX proteins in the heart.

  6. These results show that dfmr1 acts in a neuron type-specific activity-dependent manner for sculpting dendritic arbors during early-use, critical period development of learning and memory circuitry in the Drosophila brain.

  7. upon the stimulation of replication stress, dFMR1 is associated with chromatin in a domain-specific manner, which is essential for its ability to induce the phosphorylation of H2Av (show H2AFV ELISA Kits).

  8. FMRP inhibits translation by binding directly to the L5 protein on the 80S ribosome.

  9. FMRP negatively regulates HSPG (show SDC2 ELISA Kits) co-receptors controlling trans-synaptic signaling during synaptogenesis

  10. FMRP and Ataxin-2 (show ATXN2 ELISA Kits) have roles in long-term olfactory habituation and neuronal translational control

Human Fragile X Mental Retardation 1 (FMR1) interaction partners

  1. FMR1 gene mutation is associated with fragile X syndrome.

  2. This large study did not demonstrate any substantial association between normal-range FMR1 repeat lengths and reproductive parameters

  3. FMR1 is a highly conserved gene whose interpretation and effect on outcomes remains controversial in the reproductive health setting. Recent re-evaluations of the commonly accepted normal range have yielded interesting tools for possibly explaining unexpected outcomes in assisted reproduction

  4. Our results indicate that there is a potential association between FMR1 intermediate expanded alleles and Parkinson disease.

  5. FMR1 Gene Missense SNPs

  6. Data show that CGG repeats within the testes of a fetus carrying a full Fragile X syndrome (FXS) mutation and another fetus carrying mosaicism FXS mutation in fragile X mental retardation 1 protein (FMR1).

  7. Despite increasing use, FMR1 CGG repeats in the normal range cannot be used as a predictor of ovarian response to gonadotrophin stimulation

  8. Results suggest that the skewed X chromosome inactivation of the normal FMR1 allele may be a risk factor for the development of fragile-X-associated tremor/ataxia (show USP14 ELISA Kits) syndrome

  9. Triplet expansion cytosine-guanine-guanine mutation dynamics of the FMR1 gene were observed in a family with primary ovarian insufficiency and tremor-ataxia (show USP14 ELISA Kits) syndrome.

  10. Full mutation/deletion FMR1 mosaicism was identified in five males with Fragile X syndrome.

Zebrafish Fragile X Mental Retardation 1 (FMR1) interaction partners

  1. We identified thousands of clustered RNA editing sites in the zebrafish transcriptome and showed that Fmrp biochemically interacts with the Adar2a protein. The expression levels of the adar (show ADAR ELISA Kits) genes and Adar2 (show ADARB1 ELISA Kits) protein increased in fmr1-/- zebrafish

  2. Loss-of-function fmr1 mutants carrying an anti-fmr1 miRNA transgene show abnormal neuronal morphology and connectivity similar to that seen in human fragile X syndrome.

Mouse (Murine) Fragile X Mental Retardation 1 (FMR1) interaction partners

  1. Study showed that Fmr1 knock-out astrocytes affect the dendritic arborization of all subtypes of hippocampal neurons and that select populations of hippocampal neurons are more effected by this astrocyte-mediated developmental delay; specifically, the stellate neurons grown on Fmr1 knock-out astrocytes exhibit the most pervasive developmental delays

  2. The data reveal an age-dependent deficit in long-term potentiation in Fmr1KO mice, which may correlate to some of the complex age-related deficits in Fragile X syndrome.

  3. increased white matter seen in the FMR1-KO-FVB could be highlighting a structural over-connectivity, which could lead to some of the behavioral abnormalities seen with the FMR1-KO-FVB mice

  4. Study shows deficits in habituation of neural responses to repeated sounds in the Fragile X Mental Retardation gene (Fmr1) KO mice as seen in humans with fragile X syndrome.

  5. we find abnormal patterns of coupling between theta and gamma oscillations in perisomatic and dendritic hippocampal CA1 (show CA1 ELISA Kits) local field potentials of the Fmr1 knockout mice.

  6. This study demonstrated that in the active phase of the circadian cycle, Fmr1 KO mice are hyperactive, and demonstrate reduced anxiety and impaired learning and memory.

  7. Study reveals a mechanism for the local regulation of translation by miR (show MLXIP ELISA Kits)-181d and FMRP during axon development.

  8. Results indicate that, while the fragile X (Fmr1) mouse model effectively recapitulates many molecular and cellular aspects of fragile X syndrome, the cognitive profile of Fmr1 mice generally does not recapitulate the primary cognitive deficits in the human syndrome, even when diverse and challenging tasks are imposed.

  9. the absence of fragile X mental retardation protein has divergent effects on the function of individual types of ion channels not only between brain regions

  10. Results of our study suggest that the eIF4E (show EIF4E ELISA Kits)/Fmr1 double mutant mouse may be a reliable model to study cognitive dysfunction in the context of autism spectrum disorder.

FMR1 Antigen Profile

Antigen Summary

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Gene names and symbols associated with FMR1

  • CG6203 gene product from transcript CG6203-RC (Fmr1) antibody
  • fragile X mental retardation 1 (FMR1) antibody
  • fragile X mental retardation 1 (Fmr1) antibody
  • fragile X mental retardation 1 (fmr1) antibody
  • fragile X mental retardation syndrome 1 (Fmr1) antibody
  • AT24755 antibody
  • BcDNA:GM08679 antibody
  • cg6203 antibody
  • dfmr antibody
  • dfmr1 antibody
  • dFmrp antibody
  • dfxr antibody
  • dfxr1 antibody
  • dFXRP antibody
  • Dmel\\CG6203 antibody
  • dmfr1 antibody
  • EP(3)3517 antibody
  • fmr antibody
  • Fmr-1 antibody
  • fmr1 antibody
  • Fmrp antibody
  • FRAXA antibody
  • FXR antibody
  • POF antibody
  • POF1 antibody
  • zFMR1 antibody

Protein level used designations for FMR1

CG6203-PA , CG6203-PB , CG6203-PC , CG6203-PD , CG6203-PE , CG6203-PF , CG6203-PG , CG6203-PH , CG6203-PI , Fmr1-PA , Fmr1-PB , Fmr1-PC , Fmr1-PD , Fmr1-PE , Fmr1-PF , Fmr1-PG , Fmr1-PH , Fmr1-PI , Fragile-X mental retardation protein , Fragile-X-related , dFmr1 , drosophila fragile X mental retardation protein , fragile X , fragile X mental retardation , fragile X mental retardation 1 , fragile X mental retardation gene , fragile X mental retardation protein , fragile X protein , fragile X related protein , fragile X-related , fragile x related , fragile-X , fragile X mental retardation protein 1 , fragile X mental retardation protein 1 homolog , fragile X mental retardation syndrome 1 homolog , fragile X mental retardation-1 protein , protein FMR-1 , ragile X mental retardation protein , fragile X mental retardation 1 protein , FMRP , mFmr1p

GENE ID SPECIES
37528 Drosophila melanogaster
465894 Pan troglodytes
2332 Homo sapiens
481070 Canis lupus familiaris
24948 Rattus norvegicus
259191 Danio rerio
422395 Gallus gallus
100155078 Sus scrofa
507482 Bos taurus
100172902 Pongo abelii
14265 Mus musculus
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