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GCH1 Proteins

(GTP Cyclohydrolase 1 (GCH1))
This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described\; however, not all variants give rise to a functional enzyme. [provided by RefSeq, Jul 2008].
GCH1 Protein (AA 1-250) (GST tag) GCH1 Protein (AA 1-250) (GST tag) GCH1 Protein (AA 1-250) (GST tag) (ABIN1354910)

GCH1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

GCH1 Protein (AA 84-172) (GST tag) GCH1 Protein (AA 84-172) (GST tag) GCH1 Protein (AA 84-172) (GST tag) (ABIN1354912)

GCH1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

GCH1 Protein (AA 16-250) (His tag) (ABIN7422661)

GCH1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % WB, PC, SDS, Imm

GCH1 Proteins by Origin

Find GCH1 Proteins for a variety of species such as anti-Human GCH1, anti-Rat GCH1, anti-Chicken GCH1. The species listed below are among those available. Click on a link to go to the corresponding products.

GCH1 Proteins by Source

Here you will find GCH1 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

GCH1 Proteins by Protein Type

Here you can find GCH1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

GCH1 Proteins by Application

Find GCH1 Proteins validated for a specific application such as ELISA, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular GCH1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1354910
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1354912
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7422661
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3080453
Quantity 1 mg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2750202
Quantity 5 applications
Datasheet Datasheet
Reactivity Euglena gracilis
Source Yeast
Validations
Cat. No. ABIN1461743
Quantity 1 mg
Datasheet Datasheet
Reactivity Velvet bean (Mucuna pruriens)
Source Yeast
Validations
Cat. No. ABIN1608968
Quantity 1 mg
Datasheet Datasheet
Reactivity Rainbow Trout
Source Yeast
Validations
Cat. No. ABIN1608986
Quantity 1 mg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1474106
Quantity 1 mg
Datasheet Datasheet
Reactivity Chicken
Source Yeast
Validations
Cat. No. ABIN1459043
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our GCH1 Proteins

Widder, Chen, Li, Dikalov, Thöny, Hatakeyama, Harrison: "Regulation of tetrahydrobiopterin biosynthesis by shear stress." in: Circulation research, Vol. 101, Issue 8, pp. 830-8, (2007) (PubMed).

Aliases for GCH1 Proteins

GTP cyclohydrolase 1 (GCH1) Proteins
GTP cyclohydrolase 1 (Gch1) Proteins
GTP cyclohydrolase 1 (gch1) Proteins
GTP cyclohydrolase 1 (Weevi_1190) Proteins
GTP cyclohydrolase 1 (Halhy_0838) Proteins
GTP cyclohydrolase 1 (Sinme_1220) Proteins
GTP cyclohydrolase 1 (Sphch_1077) Proteins
GTP cyclohydrolase 1-like (LOC100136794) Proteins
DYT5 Proteins
DYT5a Proteins
DYT14 Proteins
GCH Proteins
Gch Proteins
gch1a Proteins
GTP-CH Proteins
GTP-CH-1 Proteins
GTPCH Proteins
GTPCH1 Proteins
HPABH4B Proteins
MGC89622 Proteins
wu:fc16b10 Proteins
zgc:195269 Proteins
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