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Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) ELISA Kits

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. Additionally we are shipping Glycoprotein Ib (Platelet), alpha Polypeptide Antibodies (196) and Glycoprotein Ib (Platelet), alpha Polypeptide Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat GP1BA GP1BA 691992  
GP1BA 14723 O35930
GP1BA 2811  
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Top Glycoprotein Ib (Platelet), alpha Polypeptide ELISA Kits at antibodies-online.com

Showing 3 out of 9 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.66 ng/mL 0.78-50 ng/mL 96 Tests Log in to see 9 to 11 Days
$700.00
Details
Mouse 11.72 pg/ml 46.88-3000 pg/mL   96 Tests Log in to see 11 to 13 Days
$910.56
Details
Dog 0.039 ng/ml 0.156-10 ng/mL   96 Tests Log in to see 11 to 13 Days
$1,026.67
Details

More ELISA Kits for Glycoprotein Ib (Platelet), alpha Polypeptide Interaction Partners

Cow (Bovine) Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) interaction partners

  1. both the gpIb-VWF (show VWF ELISA Kits) interaction and the integrin alpha(2 (show ITGA2 ELISA Kits))beta(1)-collagen interaction contribute to platelet adhesion under high shear stress; integrin alpha(II (show GSTA3 ELISA Kits))beta(1) makes a greater contribution to adhesion to type I collagen because less VWF (show VWF ELISA Kits) is bound

Mouse (Murine) Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) interaction partners

  1. Thrombin (show F2 ELISA Kits) cleavage of platelet PAR4 (show F2RL3 ELISA Kits) promotes leukocyte recruitment to sites of vascular injury. This process is negatively regulated by GPIbalpha.

  2. GPIbalpha-mediated interactions between platelets and endothelial cells, as well as leukocytes, support innate immune cell recruitment and promote arteriogenesis-establishing platelets as critical players in this process.

  3. Atherosclerosis reduction in mice lacking GPIbalpha may not result from the defective GPIbalpha-ligand binding, but more likely is a consequence of functional defects of GPIbalpha-/- platelets and reduced blood platelet counts.

  4. Data suggest that targeting platelet receptor glycoprotein Ibalpha (GPIbalpha)-von Willebrand factor VWF (show VWF ELISA Kits)-A1 binding interface may offer a therapeutic approach to reducing platelet-driven thrombosis.

  5. Following endothelial damage, platelet cross-linking during closure of the vessel lumen is mediated by GPIbalpha-VWF (show VWF ELISA Kits) interactions.

  6. Platelet IKKbeta (show IKBKB ELISA Kits) deficiency increases the formation of injury-induced arterial neointimal tissue via delayed glycoprotein Ibalpha shedding.

  7. these data demonstrate that coordinated expression of GPIbalpha and filamin (show FLNA ELISA Kits) is required for efficient trafficking of either protein to the cell surface, and for production of normal-sized platelets.

  8. Desialylation of platelet VWFR therefore triggers platelet clearance and primes GPIbalpha and GPV (show GP5 ELISA Kits) for MP-dependent cleavage.

  9. miscarriage occurred in the majority of pregnancies in a model of anti-GPIbalpha-mediated fetal and neonatal immune thrombocytopenia (FNIT), which was far more frequent than in anti-integrinbeta3-mediated FNIT

  10. Data show that the surface-bound VWF (show VWF ELISA Kits) appears as a large, linear structure on the surface of 50% of the PT-VWD (show VWF ELISA Kits) platelets.

Human Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) interaction partners

  1. GPIb alpha plays a critical role in the co-localization of thrombin (show F2 ELISA Kits) and factor XI and the resultant efficient activation of FXI (show F11 ELISA Kits)

  2. Hemoglobin interaction with GP1balpha induces platelet activation and apoptosis: a novel mechanism associated with intravascular hemolysis.

  3. Both GPIbalpha and PAR4 (show PAWR ELISA Kits) are required for thrombin (show F2 ELISA Kits)-induced reactive oxygen species formation

  4. Report no relationship, between polymorphisms of platelet membrane glycoprotein Ibalpha and risk of coronary heart disease in Chinese Han population.

  5. Molecular analysis demonstrated a novel homozygous c.800C>G substitution in GP1BA exon 2 leading to a serine 267 Ter (show TECR ELISA Kits) stop codon in all 3 siblings

  6. Whereas VWF (show VWF ELISA Kits)-D'D3 is the major regulator of soluble VWF (show VWF ELISA Kits) binding to platelet GpIbalpha, both the D'D3-domain and N-terminal peptide regulate platelet translocation and thrombus formation.

  7. Data indicate that GPIbalpha clustering induced by anti-GPIbalpha N-terminus antibody causes integrin alphaIIbbeta3-dependent platelet aggregation, phagocytosis, and rapid platelet clearance in the liver.

  8. Data show that force can switch the kinetics of bond formation between A1 domain of von Willebrand factor (VWF (show VWF ELISA Kits)) and glycoprotein Ibalpha (GPIbalpha).

  9. data indicated that GPIIb-IIIa and GPIb levels are mainly affected by platelet size (MPV) but not by their genetic variations; in some acute coronary syndrome patients, production of large platelets with high GPIIb-IIIa and GPIb contents might be stimulated by elevated thrombopoietin (show THPO ELISA Kits)

  10. Data indicate a G > T in platelet glycoprotein Ib alpha polypeptide (show ITGAE ELISA Kits) (GP1BA) gene, resulting in a Trp (show TBPL1 ELISA Kits) to Leu amino acid change at residue 246 (p.W246L), and this mutation was absent in his unaffected mother and also in the 100 controls.

Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA) Antigen Profile

Antigen Summary

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease.

Gene names and symbols associated with GP1BA

  • glycoprotein Ib (platelet), alpha polypeptide (Gp1ba) antibody
  • glycoprotein Ib (platelet), alpha polypeptide (GP1BA) antibody
  • glycoprotein 1b, alpha polypeptide (Gp1ba) antibody
  • BDPLT1 antibody
  • BDPLT3 antibody
  • BSS antibody
  • CD42B antibody
  • CD42b-alpha antibody
  • DBPLT3 antibody
  • GP1B antibody
  • GP1BA antibody
  • GPIbA antibody
  • GPIbalpha antibody
  • VWDP antibody

Protein level used designations for GP1BA

glycoprotein 1b, alpha polypeptide , platelet glycoprotein Ib alpha chain , glycoprotein Ib (platelet), alpha polypeptide , platelet glycoprotein Ib alpha polypeptide , GP-Ib alpha , glycoprotein Ibalpha , antigen CD42b-alpha , platelet membrane glycoprotein 1b-alpha subunit , GPIb-alpha , GPIbA

GENE ID SPECIES
691992 Rattus norvegicus
420059 Gallus gallus
468166 Pan troglodytes
504977 Bos taurus
14723 Mus musculus
2811 Homo sapiens
403638 Canis lupus familiaris
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