anti-Growth Associated Protein 43 (GAP43) Antibodies

The protein encoded by GAP43 has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. Additionally we are shipping GAP43 Kits (49) and GAP43 Proteins (20) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GAP43 2596 P17677
GAP43 14432 P06837
GAP43 29423 P07936
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Top anti-GAP43 Antibodies at

Showing 10 out of 280 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-GAP43 AntibodyTitration: 1.0 µg/mL <br /> Positive Control: 293T Whole Cell 100 μL Log in to see 2 to 3 Days
Chicken Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of GAP43 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of GAP43 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
Human Rabbit Un-conjugated IHC (p), WB Anti-GAP43 antibody, IHC(P) IHC(P): Human Meningeoma Tissue 100 μg Log in to see 4 to 6 Days
Chicken Mouse Un-conjugated IHC (fro), IF, IHC (p), IP, WB 0.1 mg Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IF, IHC (p), WB Immunohistochemical analysis of Paraffin-Embedded Rat Tissue Brain Sections using GAP43 antibody Western blot analysis of Rat brain tissue lysis using GAP43 antibody 0.1 mg Log in to see 6 to 8 Days
Cat Sheep Un-conjugated ICC, IF, IHC, IHC (fro), IHC (p), WB Western Blot: GAP-43 Antibody [NBP1-41123] - Total protein from Human, Mouse and Rat brain, and SHSY-5Y cells was separated on a 12% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/ml anti-GAP43 in 1% non-fat milk in TBST and detected with an anti-sheep HRP secondary antibody using chemiluminescence. Immunocytochemistry/Immunofluorescence: GAP-43 Antibody [NBP1-41123] - Staining of a mature retinal ganglion cell demonstrating axon outgrowth. 0.1 mL Log in to see 7 to 9 Days
Human Mouse Un-conjugated IHC (fro), IHC (p), WB Anti- GAP43 antibody, IHC(P) IHC(P): Rat Cardiac Muscle Tissue 100 μg Log in to see 4 to 6 Days
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IF 0.1 mL Log in to see 6 to 8 Days
Chicken Rabbit Un-conjugated ICC, IHC (fro), IF, IHC (p), IHC, WB Region CA1-CA4 of the hippocampus showing strong GAP-43 staining in cell processes and neutropil using ABIN152489. Immunofluorescence of GAP-43 (green), a molecular marker of neurite outgrowth, demonstrates intense staining in overexpressing wild-type PS-1 (E) PC-12 cells. (Teo, et al, 2005) 0.1 mL Log in to see 7 to 9 Days

GAP43 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-GAP43 Antibodies

  1. Chicken Polyclonal GAP43 Primary Antibody for ICC, IHC (fro) - ABIN152489 : Ferguson, Muir: MMP-2 and MMP-9 increase the neurite-promoting potential of schwann cell basal laminae and are upregulated in degenerated nerve. in Molecular and cellular neurosciences 2000 (PubMed)
    Show all 44 Pubmed References

  2. Cat (Feline) Polyclonal GAP43 Primary Antibody for ICC, IF - ABIN448340 : Benowitz, Goldberg, Madsen, Soni, Irwin: Inosine stimulates extensive axon collateral growth in the rat corticospinal tract after injury. in Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)
    Show all 25 Pubmed References

  3. Chicken Polyclonal GAP43 Primary Antibody for ICC, IF - ABIN314178 : Zuo, Neubauer, Graham, Krekoski, Ferguson, Muir: Regeneration of axons after nerve transection repair is enhanced by degradation of chondroitin sulfate proteoglycan. in Experimental neurology 2002 (PubMed)
    Show all 10 Pubmed References

  4. Chicken Polyclonal GAP43 Primary Antibody for IHC (fro), IHC (p) - ABIN314179 : Woolf, Reynolds, Molander, OBrien, Lindsay, Benowitz: The growth-associated protein GAP-43 appears in dorsal root ganglion cells and in the dorsal horn of the rat spinal cord following peripheral nerve injury. in Neuroscience 1990 (PubMed)
    Show all 9 Pubmed References

  5. Human Polyclonal GAP43 Primary Antibody for IHC (p), WB - ABIN3043685 : Chen, Wei, Nie, Lin, Tian, Liu, Yu, Cheng, Yan, Wang, Liu, Deng, Lai, Zhou, Zhang, Lin, Chen: ?-Asarone prevents autophagy and synaptic loss by reducing ROCK expression in asenescence-accelerated prone 8 mice. in Brain research 2014 (PubMed)
    Show all 5 Pubmed References

  6. Human Monoclonal GAP43 Primary Antibody for IF, WB - ABIN968793 : Chapman, Estep, Storm: Palmitylation of neuromodulin (GAP-43) is not required for phosphorylation by protein kinase C. in The Journal of biological chemistry 1993 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal GAP43 Primary Antibody for IF, WB - ABIN968792 : Cimler, Andreasen, Andreasen, Storm: P-57 is a neural specific calmodulin-binding protein. in The Journal of biological chemistry 1985 (PubMed)
    Show all 4 Pubmed References

  8. Human Monoclonal GAP43 Primary Antibody for IHC (fro), IHC (p) - ABIN3043645 : Nie, Deng, Yang, Liu, Zhang, Wen: Axonal regeneration and remyelination evaluation of chitosan/gelatin-based nerve guide combined with transforming growth factor-?1 and Schwann cells. in Cell biochemistry and biophysics 2014 (PubMed)
    Show all 4 Pubmed References

  9. Chicken Monoclonal GAP43 Primary Antibody for IHC, IHC (fro) - ABIN448371 : Murakami, Ito, Hagiwara, Kobayashi, Hoshikawa, Takagi, Kojima, Tamiya-Koizumi, Sobue, Ichihara, Suzuki, Banno, Nozawa, Murate: Sphingosine kinase 1/S1P pathway involvement in the GDNF-induced GAP43 transcription. in Journal of cellular biochemistry 2011 (PubMed)
    Show all 2 Pubmed References

  10. Cat (Feline) Polyclonal GAP43 Primary Antibody for IHC (fro), IF - ABIN2473748 : Boldt, Kling, Moosdorf, Hempelmann: Enoximone treatment of impaired myocardial function during cardiac surgery: combined effects with epinephrine. in Journal of cardiothoracic anesthesia 1992 (PubMed)
    Show all 4 Pubmed References

More Antibodies against GAP43 Interaction Partners

Human Growth Associated Protein 43 (GAP43) interaction partners

  1. Findings show high level of both YKL-40 (show CHI3L1 Antibodies) and GAP-43 in CSF (show CSF2 Antibodies) of older women with suicidal ideation which suggest that a disrupted synaptic glial functioning and inflammation may be related to the aetiology of suicidal ideation in older adults.

  2. associations of neuromodulin and neurogranin (show NRGN Antibodies) to Alzheimer's disease

  3. Copy-number variations are enriched for GAP43 and other neurodevelopmental genes in children with developmental coordination disorder.

  4. Downregulation of GAP43 promotes gliomas.

  5. The peripheral neuropathies lead to an initial increase in GAP-43 gene expression as a potential mechanism of regeneration, which is not sustained in neuropathies of long duration.

  6. Results show that PKC (show PRRT2 Antibodies)-dependent phosphorylation of GAP43 plays a critical role in regulating postsynaptic gephyrin (show GPHN Antibodies) aggregation in developing GABAergic synapses.

  7. increased expression of TH and GAP43 might be a molecular mechanism for left atrial myoelectricity remodeling of aging atrial fibrillation patients, which might be potential therapeutic targets of atrial fibrillation.

  8. GAP43 is seemingly a highly sensitive marker for peripheral nerve sheath tumors

  9. The results showed that the decreased GAP-43 levels induced by glutamate (show GRIN1 Antibodies) could be partially reversed by the presence of NRG-1beta

  10. Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 (show LYPLA1 Antibodies) and acyl-protein thioesterase-2 (show LYPLA2 Antibodies) with that of proto-oncogene (show RAB1A Antibodies) H-ras (show HRAS Antibodies) product and growth-associated protein-43

Mouse (Murine) Growth Associated Protein 43 (GAP43) interaction partners

  1. hnRNP (show HNRNPH2 Antibodies)-Q1-mediated repression of Gap-43 mRNA translation provides an additional mechanism for regulating GAP-43 expression and function and may be critical for neuronal development.

  2. The GASP (show GPRASP1 Antibodies)-43 is involves in the orientation of cell division by interacting with Galphai.

  3. Trimethyltin decreased synaptophysin (show SYP Antibodies) but not GAP-43 expression in the mouse hippocampus.

  4. Antiretroviral drugs may recruit the HuD (show ELAVL4 Antibodies)-GAP43 pathway, potentially contributing to a response to the antiretroviral neuronal toxicity.

  5. KSRP (show KHSRP Antibodies) modulation of GAP-43 mRNA stability restricts axonal outgrowth in embryonic hippocampal neurons.

  6. these findings suggest that GAP-43 is dynamically involved in early postnatal and adult hippocampal neurogenesis and synaptic connectivity, possibly contributing to the GAP-43+/- behavioral phenotype.

  7. In this review, GAP-43 in vivo knockdown in olivary neurons leads to the atrophy of their climbing fibers and a reduction in the ability to sprout toward surrounding denervated Purkinje cells.

  8. GAP-43 is required to sustain synaptic stability and promote the initiation of axonal regrowth

  9. In vitro results indicated that GAP43 is indeed expressed in both myoblasts and differentiating myotubes, and its cellular localization changes dramatically during maturation.

  10. Initial emergence of hollows in the somatosensory cortex is no different between GAP43 heterozygous mice and nonheterozygous littermate controls; however, the emergence of sides and septa (show SEPT2 Antibodies) is delayed by 2 days.

Zebrafish Growth Associated Protein 43 (GAP43) interaction partners

  1. these results and GAP43 structural features, support an involvement of the protein in the dynamic intracellular Ca2 (show CA2 Antibodies)+ homeostasis, a common conserved role among the different species.

  2. The results implicate the GAP43 pathway as part of an F-actin based mechanism that both stabilizes new synapses and initiates new branches near effective synapses.

  3. The present data strongly suggest that phospho-GAP43 plays an active role in both the early and late stages of optic nerve regeneration in fish.

Cow (Bovine) Growth Associated Protein 43 (GAP43) interaction partners

  1. Both the synthetic N-terminal peptide GAP-43(1-40) and the brain-derived fragment GAP-43-3 preserved the ability to oligomerize under the action of acidic phospholipids and SDS (show SDS Antibodies).

  2. These results indicated the interaction of GAP-43 and Galpha(o (show GNAO1 Antibodies)) could accelerate conversion of depalmitoylated Galpha(o (show GNAO1 Antibodies)) but not palmitoylated Galpha(o (show GNAO1 Antibodies)) from oligomers to monomers, so as to increase the GTPgammaS binding activity of Galpha(o (show GNAO1 Antibodies)).

GAP43 Antigen Profile

Protein Summary

The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene names and symbols associated with GAP43

  • growth associated protein 43 (GAP43) antibody
  • growth associated protein 43 (Gap43) antibody
  • growth associated protein 43 L homeolog (gap43.L) antibody
  • growth associated protein 43 (gap43) antibody
  • growth associated protein 43 S homeolog (gap43.S) antibody
  • b-50 antibody
  • Basp2 antibody
  • cb310 antibody
  • gap antibody
  • gap-43 antibody
  • gap43 antibody
  • gap43a antibody
  • gap43b antibody
  • pp46 antibody

Protein level used designations for GAP43

axonal membrane protein GAP-43 , calmodulin-binding protein P-57 , growth-associated protein 43 , nerve growth-related peptide GAP43 , neural phosphoprotein B-50 , neuromodulin , neuron growth-associated protein 43 , protein F1 , brain abundant, membrane attached signal protein 2 , growth accentuating protein 43 , growth associated protein 43 b , B-50 , growth associated protein 43 a , Axonal membrane protein GAP-43 , Neuromodulin , growth-associated polypeptide

2596 Homo sapiens
100345603 Oryctolagus cuniculus
14432 Mus musculus
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29423 Rattus norvegicus
30608 Danio rerio
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493873 Felis catus
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100623423 Sus scrofa
460599 Pan troglodytes
100174106 Pongo abelii
100860764 Capra hircus
101103773 Ovis aries
103827093 Serinus canaria
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