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HLA Class II DR beta 1 (HLA-DRB1) ELISA Kits

HLA-DRB3 belongs to the HLA class II beta chain paralogues. Additionally we are shipping HLA Class II DR beta 1 Antibodies (53) and HLA Class II DR beta 1 Proteins (25) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
HLA-DRB1 3123 P01912,P01911,Q29974
HLA-DRB1    
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Top HLA Class II DR beta 1 ELISA Kits at antibodies-online.com

Showing 2 out of 7 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 49 pg/mL 125-8000 pg/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details
Mouse 12 pg/mL 39.06-2500 pg/mL 96 Tests Log in to see 9 to 11 Days
$757.89
Details

More ELISA Kits for HLA Class II DR beta 1 Interaction Partners

Human HLA Class II DR beta 1 (HLA-DRB1) interaction partners

  1. HLA-DRB1*04 alleles are associated with pulmonary tuberculosis;the subtype HLA-DRB1*04:11:01 (p = 0.0019; OR = 2.23; 95% CI = 1.34 to 3.70) was associated with susceptibility to disease, while DRB1*04:07:01 (p<0.0001; OR = 0.02; 95% CI = 0.001 to 0.33)to protection.

  2. The negative association we describe here supports the idea that the HLA-DRB1 *13 allele, possibly by its specific structural features, may as well confer resistance to several other AIDs.

  3. Data indicate that the strongest risk factor for systemic juvenile idiopathic arthritis (sJIA) was HLA-DRB1*11.

  4. alleles DRB1*01:01, DQ4, DQ7 and DQ8 are considered as susceptible to egg allergy

  5. One of the associated variants was also found to be linked with increased expression of MERTK (show MERTK ELISA Kits) in monocytes and higher expression of MERTK (show MERTK ELISA Kits) was associated with either increased or decreased risk of developing MS, dependent upon HLA-DRB1*15:01 status.

  6. This study shows the universal applicability of the RNA-based sequencing approach to identify full-length coding sequences and to define the polymorphic content of HLA-DRB1 alleles.

  7. A limit to the divergent allele advantage model supported by variable pathogen recognition across HLA-DRB1 allele lineages.

  8. We found association of three variants in the region harboring genes encoding the class II human leukocyte antigens (HLAs): both located between HLA-DQA1 and HLA-DRB1

  9. HLA-DRB1 variants better accounted for the association between MHC and susceptibility to RA and SLE than did 3 other HLA-DRB variants.

  10. The HLA-DRB1*15 allele, the A*01/B*08/DRB1*03 haplotypes, and the homozygosity of HLA-A*01 and HLA-A*02 may play a presumptive predisposing factor in Acute Myeloblastic Leukemia.

HLA Class II DR beta 1 (HLA-DRB1) Antigen Profile

Antigen Summary

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide\; exons 2 and 3 encode the two extracellular domains\; exon 4 encodes the transmembrane domain\; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. DRB1 is present in all individuals. Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.

Gene names and symbols associated with HLA-DRB1

  • major histocompatibility complex, class II, DR beta 1 (hla-drb1) antibody
  • major histocompatibility complex, class II, DR beta 1 (HLA-DRB1) antibody
  • DRB1 antibody
  • DRw10 antibody
  • HLA-DR1B antibody
  • HLA-DRB antibody
  • MGC108235 antibody
  • SS1 antibody

Protein level used designations for HLA-DRB1

major histocompatibility complex, class II, DR beta 1 , DW2.2/DR2.2 , HLA class II histocompatibility antigen, DR-1 beta chain , MHC class II HLA-DR beta 1 chain , MHC class II HLA-DR-beta cell surface glycoprotein , MHC class II HLA-DRw10-beta , MHC class II antigen , human leucocyte antigen DRB1 , lymphocyte antigen DRB1

GENE ID SPECIES
734125 Xenopus (Silurana) tropicalis
3123 Homo sapiens
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