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HLA Class II DR beta 1 (HLA-DRB1) ELISA Kits

HLA-DRB1 belongs to the HLA class II beta chain paralogs. Additionally we are shipping HLA-DRB1 Antibodies (198) and HLA-DRB1 Proteins (25) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
HLA-DRB1 3123 P01912 , P01911 , Q29974
HLA-DRB1    
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Top HLA-DRB1 ELISA Kits at antibodies-online.com

Showing 2 out of 7 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 171 pg/mL 500-8000 pg/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details
Mouse 12 pg/mL 39.06-2500 pg/mL 96 Tests Log in to see 9 to 11 Days
$757.89
Details

More ELISA Kits for HLA-DRB1 Interaction Partners

Human HLA Class II DR beta 1 (HLA-DRB1) interaction partners

  1. The HLA-DR observed on CD4 (show CD4 ELISA Kits)+ T cells was almost exclusively cell surface-associated, while for autologous CD19 (show CD19 ELISA Kits)+ B cells, the protein could be located in the plasma membrane as well as in the cytoplasm.

  2. HLA-DRB1*04:02, DRB1*14:04, HLA-DQB1* 03:02 and DQB1*05:03 alleles and HLA-DRB1*04:02-DQB1*03:02 and HLA-DRB1*14:04-DQB1*05:03 haplotypes are genetic markers for susceptibility for pemphigus vulgaris, while DRB1*11 allelic group appears protective in Serbian population.

  3. These findings indicate the role of HLA-DRB haplotypes in AIH susceptibility and protection, in the Iranian population.

  4. HLA-DRB1*14 and DQB1*05 were associated with anti-MUSK (show MUSK ELISA Kits) antibody-positive myasthenia gravis.

  5. ur results indicated that HLA-DRB1*04:05, *04:03, *04:06 and SE alleles might be susceptibility allele for Rheumatoid arthritis in Chinese Han population of Shaanxi province, northwest of China

  6. Valpha2.3+Vbeta22+ CD4 (show CD4 ELISA Kits)+ T-cells accumulate in the lungs of HLA-DRB1*03+ patients with pulmonary sarcoidosis

  7. Results identified a novel HLA class II association for flupirtine-induced liver injury (DILI) showing HLA-DRB1*16: 01 and DQB1*05: 02 as novel genetic risk factor for DILI and confirming the important contribution of HLA genotype towards the risk of DILI generally.

  8. HLA-DRB1*11 and HLA-DRB1*14 may be used to predict the susceptibility to Helicobacter pylori infection in children with idiopathic thrombocytopenic purpura

  9. The new alleles (DRB1*03:112, DQB1*03:02:16 and DQB1*03:139)were found after the sequence-based typing of 32 530 random UK European routine blood donors suggesting that each has a maximum carriage frequency of 0.0031% in the blood donor population resident in Wales.

  10. HLA-DRB1*04 (OR 1.24, 95%CI 1.00-1.55, P = 0.0494), HLA-DRB1*08 (OR 1.45, 95%CI 1.14-1.86, P = 0.0030) and HLA-DRB1*16 (OR 1.39, 95%CI 1.04-1.87, P = 0.0269) were significantly associated with increased tuberculosis occurrence (Meta-Analysis)

HLA-DRB1 Antigen Profile

Antigen Summary

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide\; exons 2 and 3 encode the two extracellular domains\; exon 4 encodes the transmembrane domain\; and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. DRB1 is present in all individuals. Allelic variants of DRB1 are linked with either none or one of the genes DRB3, DRB4 and DRB5. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9.

Gene names and symbols associated with HLA-DRB1

  • major histocompatibility complex, class II, DR beta 1 (hla-drb1) antibody
  • major histocompatibility complex, class II, DR beta 1 (HLA-DRB1) antibody
  • DRB1 antibody
  • DRw10 antibody
  • HLA-DR1B antibody
  • HLA-DRB antibody
  • MGC108235 antibody
  • SS1 antibody

Protein level used designations for HLA-DRB1

major histocompatibility complex, class II, DR beta 1 , DW2.2/DR2.2 , HLA class II histocompatibility antigen, DR-1 beta chain , MHC class II HLA-DR beta 1 chain , MHC class II HLA-DR-beta cell surface glycoprotein , MHC class II HLA-DRw10-beta , MHC class II antigen , human leucocyte antigen DRB1 , lymphocyte antigen DRB1

GENE ID SPECIES
734125 Xenopus (Silurana) tropicalis
3123 Homo sapiens
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