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anti-Heat Shock 70kDa Protein 8 (HSPA8) Antibodies

HSPA8 encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. Additionally we are shipping HSPA8 Proteins (25) and HSPA8 Kits (19) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HSPA8 3312 P11142
Anti-Rat HSPA8 HSPA8 24468 P63018
HSPA8 15481 P63017
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Top anti-HSPA8 Antibodies at

Showing 10 out of 228 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Formalin-fixed and paraffin-embedded human brain tissue reacted with H... Western blot analysis of HSPA8 Antibody (N-term) (ABIN650754) in Hela ... 400 μL Log in to see 10 to 11 Days
Dog Goat Un-conjugated EIA, WB 20 μg Log in to see 6 to 8 Days
Beluga Mouse Un-conjugated IEM, FACS, IHC (fro), IF, IP, WB 50 μg Log in to see 6 to 8 Days
Human Goat Un-conjugated ELISA, WB ABIN185659 (2µg/ml) staining of A431 cell lysate (35µg protein in RIPA... 100 μg Log in to see 4 to 5 Days
Human Mouse Un-conjugated ICC, IF, IP, IHC, PLA, ELISA, WB Hsc70 (1F2 H5) human cell line mix copy. 50 μg Log in to see 3 to 4 Days
Arabidopsis Rabbit Un-conjugated IHC, WB WB Suggested Anti-HSPA8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... Sample type: rat brain lysatePrimary Dilution: 1:1000Image Submitted B... 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB   400 μL Log in to see 10 to 11 Days
Hamster Rabbit Un-conjugated BI, ICC, IF, IP, IHC, WB Hsc70 human Cell line mix 10ug 1 in 1000 Western Blotting. 100 μL Log in to see 3 to 4 Days
Cow Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
Hamster Rabbit Un-conjugated Func, IHC (fro), IF, IHC (p), IP, WB 25 μL Log in to see 6 to 8 Days

HSPA8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-HSPA8 Antibodies

  1. Hamster Polyclonal HSPA8 Primary Antibody for BI, ICC - ABIN361819 : Boorstein, Ziegelhoffer, Craig: Molecular evolution of the HSP70 multigene family. in Journal of molecular evolution 1994 (PubMed)
    Show all 13 references for ABIN361819

  2. Human Monoclonal HSPA8 Primary Antibody for ICC, IF - ABIN361800 : Bork, Sander, Valencia: An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 10 references for ABIN361800

  3. Beluga Monoclonal HSPA8 Primary Antibody for IEM, FACS - ABIN263940 : Welch, Suhan: Cellular and biochemical events in mammalian cells during and after recovery from physiological stress. in The Journal of cell biology 1987 (PubMed)
    Show all 7 references for ABIN263940

  4. Hamster Polyclonal HSPA8 Primary Antibody for Func, IHC (fro) - ABIN264847 : Brown, Martin, Hansen, Beckmann, Welch: The constitutive and stress inducible forms of hsp 70 exhibit functional similarities and interact with one another in an ATP-dependent fashion. in The Journal of cell biology 1993 (PubMed)
    Show all 6 references for ABIN264847

  5. Human Polyclonal HSPA8 Primary Antibody for FACS, IF - ABIN1944844 : Tsukahara, Yoshioka, Muraki: Molecular and functional characterization of HSC54, a novel variant of human heat-shock cognate protein 70. in Molecular pharmacology 2000 (PubMed)
    Show all 2 references for ABIN1944844

  6. Dog (Canine) Polyclonal HSPA8 Primary Antibody for EIA, WB - ABIN782988 : Zhang, Fan, Becker, Graff, Lee, Francomano: Comparison of gene expression profile between human chondrons and chondrocytes: a cDNA microarray study. in Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 2006 (PubMed)

  7. Human Polyclonal HSPA8 Primary Antibody for FACS, IF - ABIN650754 : Egerton, Moritz, Druker, Kelso, Simpson: Identification of the 70kD heat shock cognate protein (Hsc70) and alpha-actinin-1 as novel phosphotyrosine-containing proteins in T lymphocytes. in Biochemical and biophysical research communications 1996 (PubMed)

More Antibodies against HSPA8 Interaction Partners

Xenopus laevis Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. hsp72 (show HSPA1A Antibodies) was more potent than hsc73 in generating protective immune responses against the class Ia-negative 15/0 tumors.

Human Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. heat shock cognate 70 (HSC70) is an essential component of Aes (show AES Antibodies) foci in colorectal cancer cells.

  2. Cx43 (show GJA1 Antibodies)-Hsc70 interaction regulates cell cycle G1/S progression through a novel mechanism by which Cx43 (show GJA1 Antibodies)-Hsc70 interaction prevents the nuclear accumulation of p27 (show PAK2 Antibodies) through controlling the nuclear translocation of cyclin D1 (show CCND1 Antibodies)-CDK4 (show CDK4 Antibodies)-p27 (show PAK2 Antibodies) complex.

  3. serum HSC71 was identified as a novel serum biomarker of renal cell carcinoma (show MOK Antibodies), particularly useful in early diagnosis of clear-cell type.

  4. These findings provide further evidence that histatin 3 (show HTN3 Antibodies) may be involved in the regulation of cell proliferation, particularly during G1/S transition, via the ubiquitin-proteasome system of p27(Kip1 (show CDKN1B Antibodies)) and HSC70.

  5. constitutive heat shock protein HSC70 forms granule-like structures in the cytoplasm of human cells several days after the exposure to heat stress

  6. These results indicate that CHIP decreases the Kv1.5 (show KCNA5 Antibodies) protein level and functional channel by facilitating its degradation in concert with chaperone Hsc70

  7. Active Hsc70 requires active tau to regulate microtubule assembly in vivo, suggesting that tau acts in some ways as a co-chaperone for Hsc70 to coordinate microtubule assembly.

  8. detailed and systematic investigation to characterize if there are significant differences in the CHIP in vitro ubiquitination of human Hsp70 (show HSP70 Antibodies) and Hsc70.

  9. HSP70 (show HSP70 Antibodies) binds CD91 (show LRP1 Antibodies) and TLR4 (show TLR4 Antibodies) on decidual CD1a (show CD1A Antibodies)(+) dendritic cells, causes their maturation, and increases IL-15 (show IL15 Antibodies) in the context of Th1 (show TH1L Antibodies) cytokine/chemokine (show CCL1 Antibodies) domination, which could support immune response harmful for ongoing pregnancy.

  10. LAP1 (show ANPEP Antibodies) mutations are associated with severe dystonia, cerebellar atrophy and cardiomyopathy.

Cow (Bovine) Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Single-particle fluorescence imaging tracks the dynamics of Hsc70 and its clathrin substrate in real time.

  2. The interaction of the molecular chaperone (show HSP90AA1 Antibodies) Hsc70 (HSPA8) with recombinant PrP (show PRNP Antibodies) was investigated.

  3. Structure of clathrin coat with bound Hsc70 and auxilin (show DNAJC6 Antibodies).

  4. specific association between HSP73 and gentamicin may reduce the chaperone activity of HSP73 in vitro and/or in vivo

  5. report role of HSC70 in the regulation of NMT

  6. studied the process of disassembly by using cryo-electron microscopy to identify the initial binding site of Hsc70 on clathrin-C58J baskets at pH 6, under which conditions disassembly does not proceed further. Hsc70 interactions involve two sites

  7. Coats assembled from recombinant clathrin are good substrates for ATP- and auxilin (show DNAJC6 Antibodies)-dependent, Hsc70-catalyzed uncoating.

  8. The structure of an Hsp110 (show HSPH1 Antibodies):Hsc70 nucleotide exchange complex, is reported.

  9. analysis of the formation of a stable complex between chaperonin-containing TCP-1 (show CCT6A Antibodies) (CCT (show TCP1 Antibodies)) and Hsc70

  10. Elevated expression of bovine heat shock cognate (hsc)70 protein increases diabetes and inflammation following islet beta cell damage in a transgenic mouse model.

Mouse (Murine) Heat Shock 70kDa Protein 8 (HSPA8) interaction partners

  1. Hspa8 plays a vital role in genetic differences in responses to stress and ethanol and their interactions

  2. PTEN-like domains of GAK and auxilin are not essential for Hsc70-dependent chaperoning and uncoating of clathrin, but depending on the tissue, these domains appear to increase the efficiency of these co-chaperones.

  3. mass spectrometry-based proteomic analysis identified heat shock cognate 70 (HSC70) as a novel binding protein of FSP27 (show CIDEC Antibodies)

  4. These findings indicate that wild type ILK and the non-oncogenic ILK(R211A) mutation comprise a cardioprotective module with Hsp/c70.

  5. these data provide evidence for Hsc70 as a novel neuronal interactor of NF-kappaB (show NFKB1 Antibodies) p65 (show NFkBP65 Antibodies).

  6. In heat stress conditions, Hsp73 is mobilized to prevent apoptosis in the testes and epididymis, and assists Hsp72 (show HSPA1A Antibodies) in the repair of stress-altered protein conformations.

  7. 70-kDa heat shock cognate protein hsc70 mediates calmodulin (show Calm2 Antibodies)-dependent nuclear import of the sex-determining factor SRY (show SRY Antibodies).

  8. Hsc70, Hdj1 (show DNAJB1 Antibodies) and Hdj2 (show DNAJA1 Antibodies) interact with soluble and fibrillar alpha-synuclein (show SNCA Antibodies)

  9. BAG3 (show BAG3 Antibodies) and Hsc70 interact with actin capping protein (show TMOD4 Antibodies) CapZ (show CAPZA1 Antibodies) to maintain myofibrillar integrity under mechanical stress.

  10. In this study, we report an identification of Hsc70 (Heat shock cognate protein 70) as a critical mediator of RGS9-2 expression that is specifically recruited to the intrinsically disordered C-terminal domain of RGS9-2 following dissociation from R7BP.

HSPA8 Antigen Profile

Protein Summary

This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with HSPA8

  • heat shock 70kDa protein 8 (hspa8) antibody
  • heat shock 70kDa protein 8 (HSPA8) antibody
  • heat shock 70kDa protein 8 (Hspa8) antibody
  • heat shock protein 8 (Hspa8) antibody
  • heat shock protein 8 (hspa8) antibody
  • 2410008N15Rik antibody
  • HSC54 antibody
  • Hsc70 antibody
  • Hsc71 antibody
  • Hsc73 antibody
  • HSP71 antibody
  • Hsp73 antibody
  • Hspa10 antibody
  • LAP1 antibody
  • NIP71 antibody
  • wu:fb01g06 antibody
  • wu:fi48b06 antibody

Protein level used designations for HSPA8

LPS-associated protein 1 , N-myristoyltransferase inhibitor protein 71 , constitutive heat shock protein 70 , heat shock 70kd protein 10 , heat shock cognate 71 kDa protein , heat shock cognate protein 54 , lipopolysaccharide-associated protein 1 , Hsc70 ATPase , heat shock 70 kDa protein 8 , heat shock 70kd protein 10 (HSC71) , heat shock cognate 71 kD protein , Heat shock cognate protein 70 , heat shock 70kD protein 8 , heat shock protein 8 , heat shock protein A8 , heat shock cognate 70 , heat shock cognate 71 kDa protein-like protein , heat shock protein 70 cognate , heat shock cognate hsc73 , heat shock protein cognate 70 , heat shock 70kDa protein 8 , heat shock cognate 71-kd protein

379319 Xenopus laevis
3312 Homo sapiens
281831 Bos taurus
24468 Rattus norvegicus
395853 Gallus gallus
479406 Canis lupus familiaris
100009679 Equus caballus
100172711 Pongo abelii
15481 Mus musculus
573376 Danio rerio
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