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Heme Oxygenase (Decycling) 1 Proteins (HMOX1)

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Additionally we are shipping Heme Oxygenase (Decycling) 1 Antibodies (319) and Heme Oxygenase (Decycling) 1 Kits (54) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HMOX1 3162 P09601
HMOX1 15368 P14901
HMOX1 24451 P06762
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Top Heme Oxygenase (Decycling) 1 Proteins at antibodies-online.com

Showing 10 out of 35 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$242.00
Details
HOST_Escherichia coli (E. coli) Rat His tag   100 μg Log in to see 3 to 4 Days
$457.60
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$313.50
Details
Yeast Mouse His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Wild boar His tag,GST tag 100 μg Log in to see 11 to 13 Days
$704.00
Details
HOST_Escherichia coli (E. coli) Human His tag,S tag 100 μg Log in to see 11 to 13 Days
$633.60
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse His tag   100 μg Log in to see 11 to 13 Days
$739.20
Details

HMOX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,

Rat (Rattus) ,

Top referenced Heme Oxygenase (Decycling) 1 Proteins

  1. Rat (Rattus) HMOX1 Protein expressed in Escherichia coli (E. coli) - ABIN1686745 : Brydun, Watari, Yamamoto, Okuhara, Teragawa, Kono, Chayama, Oshima, Ozono: Reduced expression of heme oxygenase-1 in patients with coronary atherosclerosis. in Hypertension research : official journal of the Japanese Society of Hypertension 2007 (PubMed)
    Show all 5 references for ABIN1686745

  2. Human HMOX1 Protein expressed in Escherichia coli (E. coli) - ABIN666727 : Soares, Brouard, Smith, Bach: Heme oxygenase-1, a protective gene that prevents the rejection of transplanted organs. in Immunological reviews 2002 (PubMed)
    Show all 2 references for ABIN666727

More Proteins for Heme Oxygenase (Decycling) 1 (HMOX1) Interaction Partners

Soybean (Glycine max) Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. study evaluated the time-course of HO-1 and catalase (show CAT Proteins) gene expressions in nodules and roots of soybean plants subjected to cadmium treatment

Xenopus laevis Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. Data suggest expression of hsp32 is up-regulated in kidney epithelial cells upon in vitro exposure to heavy metal water pollutants (Cd, As) or proteasomal inhibitors (MG132, withaferin A, celastrol); heat shock may be synergistic factor.

Zebrafish Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. Bach1 (show BACH1 Proteins) regulates the liver specificity and transience of the Nrf2a (show NFE2L2 Proteins)-dependent induction of hmox1a and that heme mediates this regulation through Bach1 (show BACH1 Proteins) inhibition based on its level in each tissue.

Arabidopsis thaliana Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. HY1 confers cadmium tolerance by decreasing nitric oxide production and improving iron homeostasis.

  2. Data indicate that AtHO1 (HY1; heme oxygenase-1)-overexpressing plants generated more NO, whereas knock-down of AtHO1 expression reduced the level of nitric oxide (NO) in plants.

  3. HY1 mutant exhibited progressive salt hypersensitivity.

  4. Disrupting the binding of the AtHBP5 to haem oxygenase 1 (HY1) leads to oxidative stress.

  5. Mutation of HY1 causes UV-C hypersensitivity by impairing carotenoid and flavonoid biosynthesis and the down-regulation of antioxidant defence.

  6. HY1 and HY5 additively regulate the expression of light regulated genes and accumulation of chlorophyll and anthocyanin during early seedling development.

  7. HY1 (Heme oxygenase 1) plays an important role in salt acclimation.

  8. all members of the HO1 subfamily (HY1, HO3 and HO4) are active monomeric HOs and can convert haem to BV IXalpha using spinach Fd (ferredoxin) as an electron donor

Synechocystis PCC 6803 Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. HO2 (show HMOX2 Proteins) has an activity high enough to substitute for HO1 under aerobic conditions.

Human Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. Inhibited HO-1 expression attenuated the hypermethylation of CDKN2B (show CDKN2B Proteins) by suppressing DNMT1 (show DNMT1 Proteins), which was conducive to treatment by cooperating with decitabine.

  2. HO-1 inhibitor, ZnPP, possessed the properties of anti-tumor agent by decreasing HIF-1alpha levels, blocking VEGF production, impairing tumor angiogenesis, and inhibiting tumor growth.

  3. These findings indicate that impairment of neutrophil oxidative burst activity in sickle cell disease is associated with hemolysis and heme oxygenase-1 expression.

  4. HO-1 overexpression sharply decreases the apoptosis of bone marrow-derived mesenchymal stromal cells in the injured kidney.

  5. This review focuses on the Nrf2 (show GABPA Proteins)/HO-1 stress response mechanism as a promising target for anticancer treatment which is able to overcome resistance to therapies.

  6. Data suggest that HO-1-derived CO from tumor-associated macrophages influences, in part, E-cadherin (show CDH1 Proteins) expression and thus tumor initiation and progression.

  7. Using X-ray crystallography, the structures of several complexes of HO-1 with novel inhibitors have been elucidated, which provided insightful information regarding the salient features required for inhibitor binding.

  8. heme oxygenase-1 expression is induced by gold nanoparticles through Nrf2 (show GABPA Proteins) activation and Bach1 (show BACH1 Proteins) export in human vascular endothelial cells

  9. evaluated Abeta (show APP Proteins)-induced DNA methylation (show HELLS Proteins) status of HMOX1 at -374 promoter CpG site in blood samples from Alzheimer disease patients, patients with mild cognitive impairment, and control individuals

  10. These data suggest the role of Nrf2 (show GABPA Proteins), HO-1 and glutathione as molecular targets to improve the efficacy of low doses of bortezomib in the treatment of malignant neuroblastoma (show ARHGEF16 Proteins).

Pig (Porcine) Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. findings collectively suggest that miR (show MYLIP Proteins)-506 acts as a tumor suppressor via regulation of ROCK1 (show ROCK1 Proteins) expression and may thus be a promising therapeutic target for HCC (show FAM126A Proteins)

  2. Exogenous administration of CO exacerbated allergic symptoms, resulting in higher levels of both CO and heme oxygenase-1 expression, and a further reduction in H2S levels and CSE expression.

  3. Down-regulation of HO-1 is associated with pulmonary arterial hypertension and right ventricular failure.

  4. The study revealed the involvement of HO-1 in classical swine fever virus proliferation.

  5. The protective properties of flavonoids, such as EGCG, against endothelial inflammation may be regulated in part though induction of HO-1 and subsequent activator protein-1 signaling.

  6. Glutamate (show GRIN2C Proteins) regulates Ca2 (show CA2 Proteins)+ signals in smooth muscle cells of newborn piglet brain slice arterioles through astrocyte- and heme oxygenase-dependent mechanisms.

  7. obalt protoporphyrin prevents postictal cerebral vascular dysfunction by upregulating HO-1.

  8. Data demonstrate that lipopolysaccharides evoke a heat shock response, with an increase heat shock proteins 70 and Hsp32) and of VEGF (show VEGFA Proteins), a specific endothelial cell growth factor (show FGF1 Proteins).

  9. Interaction of soluble factors in plasma possibly generated during PICSO are not responsible for upregulation of HO-1 and VEGF mRNA.

Cow (Bovine) Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. the data were consistent with HO-1 acting as an anti-viral factor and these findings suggested that induction of HO-1 may be a useful prevention and treatment strategy against BVDV infection.

  2. These findings suggest that bronchiolar epithelial cells and macrophages up-regulate Nrf2 (show NFE2L2 Proteins) expression early in the course of infection, which results in increased expression of HO-1 within these cells.

  3. investigation of molecular mechanisms of microvascular complications in diabetes/hyperglycemia: regulation of HO-1 gene expression in aortic endothelial cells by advanced glycation end products

  4. Sickle blood increases endothelial heme oxygenase activity.

  5. data provide evidence for the involvement of the thioredoxin/thioredoxin (show TXN Proteins) receptor system, in the regulation of haem oxygenase-1 expression in aortic endothelial cells during pro-oxidant challenge

  6. Heme oxygenase-1 induction modulates hypoxic pulmonary vasoconstriction through upregulation of ecSOD/SOD3 (show SOD3 Proteins).

Mouse (Murine) Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. Tissue HO-1 exerts anti-inflammatory effects on lipopolysaccharide-induced pulmonary inflammation.

  2. Data suggest that HO-1-derived CO from tumor-associated macrophages influences, in part, E-cadherin (show CDH1 Proteins) expression and thus tumor initiation and progression.

  3. Irradiation inhibits osteoblast differentiation and mineralization of MC3T3-E1 cells through the oxidative stress-mediated activation of Nrf2 (show NFE2L2 Proteins)/HO-1 pathway.

  4. HO-1 is an essential enzyme for iron-dependent lipid peroxidation during ferroptotic cell death

  5. Data indicate that a reduced expression of heme oxygenase 1 (HO-1) was observed in sciatic nerves of diabetic mice treated with cobalt protoporphyrin IX (CoPP).

  6. we provide evidence of a crucial role of HO-1 in limiting aneurysm growth by showing that HO-1 induction by heme slows AAA (show AAAS Proteins) progression.

  7. curcumin promotes the acquisition of an alternative microglial phenotype in an HO-1-dependent manner and reduces iNOS (show NOS2 Proteins) induction and ROS (show ROS1 Proteins) production

  8. our findings demonstrated that HO-1 exerted its anti-inflammatory function through suppression of basophil maturation and activation, but promotion of basophil apoptosis

  9. HO-1 induces a paracrine signalling in macrophages via reactive oxygen species production, mediating apoptosis of heart muscle cells at later stages of myocarditis.

  10. Collectively, these results demonstrate that isorhamnetin augments the cellular antioxidant defense capacity by activating the Nrf2 (show NFE2L2 Proteins)/HO-1 pathway involving the activation of the ERK (show EPHB2 Proteins) pathway, thus protecting the C2C12 cells from H2O2-induced cytotoxicity.

Rabbit Heme Oxygenase (Decycling) 1 (HMOX1) interaction partners

  1. Ligustrazine injection possesses notable protective effects on ischemia/reperfusion injury in rabbits by increasing the expression of HO-1 in lung.

  2. Results add new evidence for the importance of HO-1 in the genesis and development of atherosclerosis and provide several possible mechanisms underlying the anti-atherosclerosis effects of HO-1

  3. the effect of HO-1 on the progression and stabilization of vulnerable plaques and the possible mechanism

  4. Heme-L-lysinate could attenuate atherosclerotic progression through upregulating HO-1 and HSP70 (show HSP70 Proteins) expression and increasing CO production.

  5. These results suggest that HO-1 is important in limiting in-stent stenosis and can be regarded as a new therapeutic target.

  6. Statins showed anti-atherosclerotic effects mediated by HO-1/eNOS (show NOS3 Proteins), restoring the [NO]/[ONOO(-)] imbalance and reducing lipid peroxidation.

  7. HO-1/CO system was activated and may be one of the protective signal pathway during pulmonary ischemia-reperfusion injury in rabbits.

  8. HO-1 contributes to vascular repair by increasing circulating endothelial progenitor cells (EPCs) derived from the bone marrow.

Heme Oxygenase (Decycling) 1 (HMOX1) Protein Profile

Protein Summary

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.

Gene names and symbols associated with HMOX1

  • heme oxygenase (decycling) 1 (HMOX1)
  • heme oxygenase 1 (HO1)
  • heme oxygenase (decycling) 1 (hmox1)
  • heme oxygenase 1 (TED4)
  • heme oxygenase (ho1)
  • heme oxygenase (CPE0214)
  • heme oxygenase 1 (ho1)
  • Heme oxygenase (ho1)
  • heme oxygenase 1 (AM1_C0205)
  • heme oxygenase 1 (CC1G_11686)
  • heme oxygenase 1 (CpipJ_CPIJ007246)
  • Heme oxygenase (Cyan7425_2962)
  • heme oxygenase (decycling) 1 (Hmox1)
  • ARABIDOPSIS THALIANA HEME OXYGENASE 1 protein
  • ATHO1 protein
  • bK286B10 protein
  • D8Wsu38e protein
  • F18A8.4 protein
  • F18A8_4 protein
  • GENOMES UNCOUPLED 2 protein
  • GUN2 protein
  • HEME OXYGENASE protein
  • HEME OXYGENASE 1 protein
  • HEME OXYGENASE 6 protein
  • Hemox protein
  • Heox protein
  • HEOXG protein
  • Hmox protein
  • Hmox1 protein
  • HMOX1D protein
  • Ho-1 protein
  • Ho1 protein
  • hsp32 protein
  • HY1 protein
  • HY6 protein
  • MGC132176 protein
  • PLASTID HEME OXYGENASE protein
  • REVERSAL OF THE DET PHENOTYPE 4 protein
  • wu:fc27c04 protein
  • zgc:65984 protein

Protein level used designations for HMOX1

heme oxygenase (decycling) 1 , heme oxygenase 1 , fc27c04 , heme oxygenase , Heme oxygenase , heat shock protein, 32-kD , HO-1 , heat shock protein 32 , heme oxygenase (decyclizing) 1 , P32 protein , hemoxygenase , heme oxygenase-1

GENE ID SPECIES
470195 Pan troglodytes
547612 Glycine max
719266 Macaca mulatta
734976 Xenopus laevis
791518 Danio rerio
817208 Arabidopsis thaliana
953483 Synechocystis sp. PCC 6803
988459 Clostridium perfringens str. 13
1012610 Thermosynechococcus elongatus BP-1
1463132 Prochlorococcus marinus subsp. marinus str. CCMP1375
1726356 Prochlorococcus marinus subsp. pastoris str. CCMP1986
1732486 Synechococcus sp. WH 8102
4718538 Prochlorococcus marinus str. AS9601
4719905 Prochlorococcus marinus str. MIT 9515
4778405 Prochlorococcus marinus str. MIT 9303
4779884 Prochlorococcus marinus str. NATL1A
4911675 Prochlorococcus marinus str. MIT 9301
5157291 Synechococcus sp. RCC307
5615689 Prochlorococcus marinus str. MIT 9215
5686060 Acaryochloris marina MBIC11017
5730157 Prochlorococcus marinus str. MIT 9211
5862292 Microcystis aeruginosa NIES-843
6012319 Coprinopsis cinerea okayama7130
6039118 Culex quinquefasciatus
7288894 Cyanothece sp. PCC 7425
3162 Homo sapiens
445512 Sus scrofa
513221 Bos taurus
15368 Mus musculus
24451 Rattus norvegicus
442987 Canis lupus familiaris
100715748 Cavia porcellus
396287 Gallus gallus
100173339 Pongo abelii
100008919 Oryctolagus cuniculus
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