anti-Hermansky-Pudlak Syndrome 4 (HPS4) Antibodies

HPS4 encodes a protein component of biogenesis of lysosome-related organelles complexes (BLOC). Additionally we are shipping HPS4 Kits (12) and HPS4 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
HPS4 89781 Q9NQG7
Anti-Mouse HPS4 HPS4 192232 Q99KG7
Anti-Rat HPS4 HPS4 304555  
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Top anti-HPS4 Antibodies at

Showing 2 out of 2 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry: HPS4 Antibody [NBP2-31898] - Staining of human stomach shows strong cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: HPS4 Antibody [NBP2-31898] - Staining of human cell line A-431 shows positivity in centrosome. 0.1 mL Log in to see 10 to 13 Days
Human Rabbit Un-conjugated IHC, ELISA, WB   200 μL Log in to see 12 to 14 Days

HPS4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,

More Antibodies against HPS4 Interaction Partners

Human Hermansky-Pudlak Syndrome 4 (HPS4) interaction partners

  1. BLOC-3 is a Rab32 (show RAB32 Antibodies) and Rab38 (show RAB38 Antibodies) guanine nucleotide exchange factor (show RASGRF1 Antibodies), with a specific function in the biogenesis of lysosome-related organelles. Silencing of the BLOC-3 subunits Hps1 (show HPS1 Antibodies) and Hps4 results in the mislocalization of Rab32 (show RAB32 Antibodies) and Rab38 (show RAB38 Antibodies).

  2. These findings suggested the involvement of HPS4 in the working memory of healthy subjects and in the executive function deficits in schizophrenia.

  3. These results suggest that the HPS4 gene confers a susceptibility to schizophrenia.

  4. Seven mutations (six previously unreported) were described in the HPS1 (show HPS1 Antibodies), HPS4, and HPS5 (show HPS5 Antibodies) genes among Hermansky-Pudlak Syndrome patients of Mexican, Uruguayan, Honduran, Cuban, Venezuelan, and Salvadoran ancestries.

  5. Data show that recombinant HPS1 (show HPS1 Antibodies)-HPS4 produced in insect cells can be efficiently isolated as a 1:1 heterodimer, and might function as a Rab9 (show RAB9A Antibodies) effector in the biogenesis of lysosome-related organelles.

  6. identification of mutations which establish HPS4 as important in Herman-Pudlak syndrome, and identification of mouse homolog light-ear gene

  7. identification as a component of two complexes, BLOC-3 and BLOC-4, involved in the biogenesis of lysosome-related organelles

  8. Hermansky-Pudlak syndrome type 4 (HPS-4) patients exhibited iris transillumination, variable hair and skin pigmentation, absent platelet dense bodies, and occasional pulmonary fibrosis and granulomatous colitis.

  9. observations demonstrate that the Hermansky-Pudlak syndrome 1(HPS1 (show HPS1 Antibodies)) and HPS4 proteins are components of a cytosolic complex that is involved in the biogenesis of lysosomal-related organelles

  10. HPS4 but not HPS3 associates with HPS1 in a complex, which we term biogenesis of lysosome-related organelles complex 3 (BLOC-3)

Mouse (Murine) Hermansky-Pudlak Syndrome 4 (HPS4) interaction partners

  1. VAMP7 mediates fusion of BLOC-1-dependent transport carriers with melanosomes, illuminate SNARE recycling from melanosomes as a critical BLOC-3-dependent step.

HPS4 Antigen Profile

Protein Summary

This gene encodes a protein component of biogenesis of lysosome-related organelles complexes (BLOC). BLOC complexes are important for the formation of endosomal-lysosomal organelles such as melanosomes and platelet dense granules. Mutations in this gene result in subtype 4 of Hermansky-Pudlak syndrome, a form of albinism. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with HPS4

  • Hermansky-Pudlak syndrome 4 (HPS4) antibody
  • Hermansky-Pudlak syndrome 4 homolog (human) (Hps4) antibody
  • Hermansky-Pudlak syndrome 4 (Hps4) antibody
  • 2010205O06Rik antibody
  • AU040608 antibody
  • BLOC-3 antibody
  • C130020P05Rik antibody
  • le antibody
  • mKIAA1667 antibody

Protein level used designations for HPS4

Hermansky-Pudlak syndrome 4 protein , light-ear protein homolog , Hermansky-Pudlak syndrome 4 protein homolog , light ear , light-ear protein , Hermansky-Pudlak syndrome 4 homolog

89781 Homo sapiens
192232 Mus musculus
304555 Rattus norvegicus
100721935 Cavia porcellus
101118387 Ovis aries
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