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anti-Interleukin 10 (IL10) Antibodies

The protein encoded by IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. Additionally we are shipping IL-10 Kits (276) and IL-10 Proteins (173) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IL10 3586 P22301
IL10 16153 P18893
IL10 25325 P29456
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Top anti-IL-10 Antibodies at

Showing 10 out of 681 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram) using Interleukin-10/IL10 Antibody . FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Human breast carcinoma (formalin-fixed, paraffin-embedded) reacted with IL10 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for IHC; clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colon tissue labeled Anti-IL-10 Polyclonal Antibody, Unconjugated (ABIN672051) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 14 to 21 Days
Human Mouse Un-conjugated ELISA, WB 0.1 mL Log in to see 5 to 7 Days
Human Rat Un-conjugated ELISA (Capture), FACS, WB Expression of IL-10 by stimulated CD14+ human monocytes. Human PBMC were stimulated for 24 hours with LPS (1.0 µg/ml final concentration) in the presence of GolgiStop™ (2 µM final concentration). The PBMC were harvested, stained with FITC-mouse anti-human CD14 antibody (FITC-M5E2), fixed, permeabilized, and subsequently stained with 0.25 µg of PE-rat anti-human IL-10 antibody (PE-JES3-9D7) following Pharmingen's staining protocol (first panel). The data reflect gating on monocytes, based on forward and side light scatter. To demonstrate specificity of staining, the binding of PE-JES3-9D7 was blocked by the preincubation of the conjugated antibody with recombinant human IL-10 (0.5 µg, middle panel), and by preincubation of the fixed/permeabilized cells with the unlabeled JES3-9D7 antibody (5.0 µg, ABIN967464, second panel) prior to staining with the PE-JES3-9D7 antibody. The quadrant markers for the bivariate dot plots were set based on the autofluorescence control, and verified with the recombinant cytokine blocking (middle panel) and unlabeled antibody (second panel) blocking specificity controls. Recombinant cytokine blocking 0.1 mg Log in to see 5 to 6 Days
Human Mouse Un-conjugated ELISA, WB 100 μL Log in to see 3 to 4 Days
Human Rabbit Un-conjugated EIA, Func, IHC (p), WB   50 μg Log in to see 6 to 8 Days
Cow Rabbit Un-conjugated IHC, ELISA, WB The IL-10 Antibody is used in Western blot to detect IL-10 in rat pancreas tissue lysate. IL10 staining in rat colon. Paraffin-embedded rat colon is stained with IL10 Antibody used at 1:100 dilution. 0.1 mg Log in to see 2 to 6 Days
Mouse Rat PE FACS   100 Tests Log in to see 6 to 8 Days
Human Mouse FITC FACS 100 Tests Log in to see 6 to 8 Days
Human Mouse PE FACS 100 Tests Log in to see 6 to 8 Days

IL10 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-IL-10 Antibodies

  1. Human Monoclonal IL-10 Primary Antibody for FACS - ABIN1107781 : Moore, Zaki: Clinical cytokine network cytometry. in Clinics in laboratory medicine 2001 (PubMed)
    Show all 10 references for ABIN1107781

  2. Human Monoclonal IL-10 Primary Antibody for FACS - ABIN1107780 : Santiago, Luca, Bertho, Azeredo-Coutinho, Coutinho: Detection of intracytoplasmic cytokines by flow cytometry. in Memórias do Instituto Oswaldo Cruz 2000 (PubMed)
    Show all 9 references for ABIN1107780

  3. Human Monoclonal IL-10 Primary Antibody for ELISA (Capture), FACS - ABIN967464 : Just, Abrams, Louie, Urbano, Wara, Nicholas, Stein, King: Influence of host genotype on progression to acquired immunodeficiency syndrome among children infected with human immunodeficiency virus type 1. in The Journal of pediatrics 1995 (PubMed)
    Show all 8 references for ABIN967464

  4. Cow (Bovine) Polyclonal IL-10 Primary Antibody for IHC, ELISA - ABIN1582204 : Shi, Diez-Freire, Jun, Qi, Katovich, Li, Sriramula, Francis, Sumners, Raizada: Brain microglial cytokines in neurogenic hypertension. in Hypertension 2010 (PubMed)
    Show all 7 references for ABIN1582204

  5. Human Polyclonal IL-10 Primary Antibody for IF (p), IHC (p) - ABIN672051 : Kou, Hu, Yao, Wang, Shen, Kang, Hong: Transforming growth factor-?1 promotes Treg commitment in nasal polyposis after intranasal steroid treatment. in Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2013 (PubMed)
    Show all 5 references for ABIN672051

  6. Human Polyclonal IL-10 Primary Antibody for EIA, FACS - ABIN952917 : Trajkov, Trajchevska, Arsov, Petlichkovski, Strezova, Efinska-Mladenovska, Sandevski, Spiroski: Association of 22 cytokine gene polymorphisms with tuberculosis in Macedonians. in The Indian journal of tuberculosis 2010 (PubMed)
    Show all 2 references for ABIN952917

  7. Human Polyclonal IL-10 Primary Antibody for EIA, Func - ABIN116099 : Roca, Di Paolo, Petruzzelli, Grandaliano, Ranieri, Schena, Gesualdo: Dexamethasone modulates interleukin-12 production by inducing monocyte chemoattractant protein-1 in human dendritic cells. in Immunology and cell biology 2007 (PubMed)
    Show all 2 references for ABIN116099

  8. Human Monoclonal IL-10 Primary Antibody for ELISA, WB - ABIN1724633 : Vieira, de Waal-Malefyt, Dang, Johnson, Kastelein, Fiorentino, deVries, Roncarolo, Mosmann, Moore: Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)

  9. Human Monoclonal IL-10 Primary Antibody for ELISA, WB - ABIN151606 : Rho, Lampe: High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays. in Journal of proteome research 2013 (PubMed)

  10. Mouse (Murine) Monoclonal IL-10 Primary Antibody for FACS - ABIN118665 : Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. in Immunological reviews 1992 (PubMed)

More Antibodies against IL-10 Interaction Partners

Human Interleukin 10 (IL10) interaction partners

  1. The IL10 promoter functional polymorphism was found to not be associated with ischemic stroke in a Chinese Uyghur population.

  2. Elevated plasma IL-10 is a potential predictor of disease severity and fatal outcome in DHF [Dengue Hemorrhagic Fever]patients.

  3. There were no significant differences between patients with Behcet's disease and controls with respect to the IL-1Ra (show IL1RN Antibodies), IL-1beta (show IL1B Antibodies), IL-2 (show IL2 Antibodies), IL-6 (show IL6 Antibodies) and the IL-10 gene polymorphism distributions. Correlations between the articular involvement and IL-1RN (show IL1RN Antibodies), the ocular involvement and the IL-1beta (show IL1B Antibodies), and the age of disease onset and the IL-2 (show IL2 Antibodies) and IL-10 polymorphisms suggest that that they could be associated with disease symptoms.

  4. IFNgamma+874 A/T and IL10-1082 G/G gene polymorphisms were found to be significantly associated with non-small cell lung cancer with 1.56- and 1.68-fold disease risk, respectively.

  5. no confirmatory evidence for the hypothesis of IL-10 and IL-18 (show IL18 Antibodies) alleles modulating the risk of cognitive impairment in Chinese Parkinson's disease patients was obtained.

  6. Study analyzed early neurobiological markers involved in inflammatory activation in newborns with a history of crack/cocaine exposure in utero and found a significant increase in inflammatory activation in newborns with a history of intrauterine crack/cocaine exposure, as assessed both by IL-6 (show IL6 Antibodies) and IL-10 measures

  7. B-cells from patients tolerant to the graft maintained higher IL-10 production after CD40 (show CD40 Antibodies) ligation, which correlates with lower CD86 (show CD86 Antibodies) expression compared to patients with chronic rejection.

  8. IL-10-1082 G/A polymorphism not significantly associated with acute rejection risk in renal transplant recipients [meta-analysis]

  9. meta-analysis results suggest that the IL-10-1082 A/G variant is associated with increased risk of nasopharyngeal carcinoma in Asian populations

  10. Reduction of Tim-3 (show HAVCR2 Antibodies)(+) Treg cells (Tregs) in osteoarthritis patients resulted in less IL-10-producing Tregs.

Mouse (Murine) Interleukin 10 (IL10) interaction partners

  1. CD26 (show DPP4 Antibodies) costimulatory blockade promotes lung allograft acceptance via reduced T cell infiltration, less expression of IL-17 (show IL17A Antibodies), and increased expression of IL-10, likely to be derived from alternatively activated macrophages.

  2. Lactobacillus curvatus WiKim38 induced significantly higher levels of IL-10 in bone marrow-derived dendritic cells.

  3. Light-emitting diode therapy increased the levels of IL-10 in a model of chronic inflammatory hyperalgesia

  4. NAD (+) regulates Treg conversion into Th17 cells and promotes homeostasis through IL-10

  5. Inhibition of Interleukin-10 Signaling Induces Microbiota-dependent Chronic Colitis in Apolipoprotein E (show APOE Antibodies) Deficient Mice.

  6. Melatonin upregulates the expression of IL-10 in the spleen and reduce the severity of experimental autoimmune encephalomyelitis

  7. Low-level stress resulted in a marked increase in the expression of the antiinflammatory cytokine IL-10 in wild-type but not BDNF (show BDNF Antibodies)-deficient mice

  8. Antiplatelet effects of clopidogrel are not significantly different between mice with and without IL-10 gene expression, although systemic exposure to clopidogrel active metabolite is significantly higher in IL-10 KO mice than in WT mice.

  9. The upregulation of IL-10 was followed by the appearance of suppressor of cytokine signaling (SOCS (show CISH Antibodies))1 (show SOCS1 Antibodies) in the presence of IL-15 (show IL15 Antibodies) and the loss of IL-10.

  10. marginal zone precursor B cell IL-10 is necessary for tolerance and controls the differentiation and position of Th17, Tfh and Tfr (show TFRC Antibodies) cells in secondary lymphoid tissues

Cow (Bovine) Interleukin 10 (IL10) interaction partners

  1. This study seems to indicate that PGE2 in cattle does not produce an anti-inflammatory effect by increasing the synthesis of IL-10.

  2. IL-10 mRNA expression increased on day 8 in the mononuclear leukocytes of pregnant cows. In a cell culture experiment, interferon-tau stimulated stimulated IL-10 mRNA expression in mononuclear leukocytes.

  3. Bovine IL-10 potently inhibits the activation of human myeloid cells in response to toll (show TLR4 Antibodies) like receptor activation.

  4. Monocytes obtained from cows with subclinical infection with MAP had upregulated expression of IL-10 and SOCS-3 (show SOCS3 Antibodies), which may have attenuated the capacity of mononuclear phagocytes to initiate inflammatory and adaptive immune responses.

Horse (Equine) Interleukin 10 (IL10) interaction partners

  1. The ability of an EHV-1 isolate to down-regulate IL-10 production might contribute to increased local inflammation and a higher risk for neurological manifestation of the disease after infection with Ab4.

  2. The data suggested in foals there is an impaired Th2 response, the immune response is Th1 (show TH1L Antibodies) biased, interferon-gamma (show IFNG Antibodies) production is qualitatively similar to adult horses, and regulatory IL-10 production by T cells is mature.

  3. serum IL-6 (show IL6 Antibodies):IL-10 ratio is likely to provide a valuable prognosticator for neonatal septicemia

  4. The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6 (show IL6 Antibodies), IL-10 and TNF-alpha (show TNF Antibodies), in horses with recurrent airway obstruction during exacerbation and in remission is reported.

Guinea Pig Interleukin 10 (IL10) interaction partners

  1. The complete open reading frame consists of 537 base pairs which encodes a protein of 179 amino acids. This cDNA sequence exhibited 87% homology with human IL-10.

Rabbit Interleukin 10 (IL10) interaction partners

  1. ICAM1 (show ICAM1 Antibodies) and IL10 were upregulated in ventilator-induced lung injury. Nuclear transcription factor AP-1 (show JUN Antibodies) may be responsible for this upregulation.

Pig (Porcine) Interleukin 10 (IL10) interaction partners

  1. These data indicate that the type 2 porcine reproductive and respiratory syndrome virus N protein plays an important role in IL-10 induction and the N-N non-covalent domain is associated with this activity.

  2. The effects of semen, spermatozoa in extender, or extender alone on the expression of TGF-beta1 (show TGFB1 Antibodies), IL-10, and IL-6 (show IL6 Antibodies) in ovarian follicles are reported.

  3. Prostaglandin E2 potentiates mesenchymal stem cell-induced IL-10+IFN-gamma (show IFNG Antibodies)+CD4 (show CD4 Antibodies)+ regulatory T cells to control transplant arteriosclerosis.

  4. Porcine reproductive and respiratory syndrome virus strain CH-1a could significantly up-regulate IL-10 production through p38 MAPK (show MAPK14 Antibodies) activation.

  5. Boar seminal plasma contained TGF- beta1 (show TGFB1 Antibodies) and IL-10 but with high individual variation.

  6. Changes in interleukin-10 mRNA expression are predictive for 9-day survival of pigs in an emergency preservation and resuscitation model.

  7. These results suggest that TNF-alpha (show TNF Antibodies) and IL-10, but not IL-6 (show IL6 Antibodies), are involved in the late reparatory phases of the experimental disk lesion.

  8. The present study shows that elevated levels of serum CRP (show CRP Antibodies) and IL-10 were associated with porcine circovirus type 2-infected piglets that subsequently developed severe PMWS.(postweaning multisystemic wasting syndrome)

  9. Subclinically porcine circovirus type 2 (PCV2)-infected pigs developed a transient PCV2-specific IL-10 response during the viremic phase of infection which coincided with the inversion of the IgM/IgG ratio.

  10. Twenty one polymorphisms in the IL10 gene have been found, including single nucleotide polymorphisms and insertion deletion polymorphisms. The chromosomal location has been mapped by FISH and radiation hybrid mapping.

Rhesus Monkey Interleukin 10 (IL10) interaction partners

  1. IL-10 produced during the immune response to malaria in this model contributes to suppression of mucosal inflammatory responses to invasive NTS (show NTS Antibodies), which may contribute to differences in the clinical presentation of NTS (show NTS Antibodies) infection in the setting of malaria.

  2. Findings demonstrate that internalization of IL-10R with the resultant impact on IL-10 signaling and dysregulation of the IL-10-mediated anti-inflammatory responses might play a crucial role in epithelial cell damage and subsequent simian immunodeficiency virus pathogenesis.

  3. IL-10 plays a crucial role in maintaining mucosal homeostasis by regulating mucosal IFNgamma and TNFalpha (show TNF Antibodies) cytokine production.

IL-10 (IL10) Antigen Profile

Protein Summary

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

Gene names and symbols associated with anti-Interleukin 10 (IL10) Antibodies

  • interleukin 10 (IL10) antibody
  • interleukin 10 (Il10) antibody
  • CSIF antibody
  • GVHDS antibody
  • Il-10 antibody
  • IL10A antibody
  • IL10X antibody
  • TGIF antibody

Protein level used designations for anti-Interleukin 10 (IL10) Antibodies

T-cell growth inhibitory factor , cytokine synthesis inhibitory factor , interleukin-10 , CSIF , IL-10 , uncharacterized protein LOC100715618 , Cytokine synthesis inhibitory factor , Interleukin-10

3586 Homo sapiens
16153 Mus musculus
25325 Rattus norvegicus
281246 Bos taurus
100034187 Equus caballus
443342 Ovis aries
403628 Canis lupus familiaris
428264 Gallus gallus
100860746 Capra hircus
100715618 Cavia porcellus
100008701 Oryctolagus cuniculus
397106 Sus scrofa
493683 Felis catus
694931 Macaca mulatta
100386149 Callithrix jacchus
469657 Pan troglodytes
101271889 Orcinus orca
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