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anti-Interleukin 10 (IL10) Antibodies

The protein encoded by IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. Additionally we are shipping IL-10 Kits (286) and IL-10 Proteins (186) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
IL10 3586 P22301
IL10 16153 P18893
IL10 25325 P29456
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Top anti-IL-10 Antibodies at

Showing 10 out of 707 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IHC (p), WB Flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram) using Interleukin-10/IL10 Antibody . FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Human breast carcinoma (formalin-fixed, paraffin-embedded) reacted with IL10 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for IHC; clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated ELISA, IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human colon tissue labeled Anti-IL-10 Polyclonal Antibody, Unconjugated (ABIN672051) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 14 to 21 Days
Human Mouse Un-conjugated ELISA, WB 0.1 mL Log in to see 5 to 7 Days
Human Mouse Fluorescein FACS Detection of IL-10 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with PMA and Calcium Ionomycin were stained with Mouse Anti-Human IL-10 Fluorescein-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
Human Rat Un-conjugated ELISA (Capture), FACS, WB Expression of IL-10 by stimulated CD14+ human monocytes. Human PBMC were stimulated for 24 hours with LPS (1.0 µg/ml final concentration) in the presence of GolgiStop™ (2 µM final concentration). The PBMC were harvested, stained with FITC-mouse anti-human CD14 antibody (FITC-M5E2), fixed, permeabilized, and subsequently stained with 0.25 µg of PE-rat anti-human IL-10 antibody (PE-JES3-9D7) following Pharmingen's staining protocol (first panel). The data reflect gating on monocytes, based on forward and side light scatter. To demonstrate specificity of staining, the binding of PE-JES3-9D7 was blocked by the preincubation of the conjugated antibody with recombinant human IL-10 (0.5 µg, middle panel), and by preincubation of the fixed/permeabilized cells with the unlabeled JES3-9D7 antibody (5.0 µg, ABIN967464, second panel) prior to staining with the PE-JES3-9D7 antibody. The quadrant markers for the bivariate dot plots were set based on the autofluorescence control, and verified with the recombinant cytokine blocking (middle panel) and unlabeled antibody (second panel) blocking specificity controls. Recombinant cytokine blocking 0.1 mg Log in to see 5 to 6 Days
Human Mouse Un-conjugated ELISA, WB 100 μL Log in to see 3 to 4 Days
Human Rabbit Un-conjugated EIA, Func, IHC (p), WB   50 μg Log in to see 6 to 8 Days
Cow Rabbit Un-conjugated IHC, ELISA, WB The IL-10 Antibody is used in Western blot to detect IL-10 in rat pancreas tissue lysate. IL10 staining in rat colon. Paraffin-embedded rat colon is stained with IL10 Antibody used at 1:100 dilution. 0.1 mg Log in to see 2 to 6 Days
Human Rat Un-conjugated ELISA, IHC, WB Western Blot: IL-10 Antibody (JES3-9D7) [NBP2-27573] - Ecombinant protein probed with RAT ANTI HUMAN INTERLEUKIN-10 followed by F(ab 0.1 mg Log in to see 5 to 7 Days
Mouse Rat PE FACS   100 Tests Log in to see 6 to 8 Days

IL10 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-IL-10 Antibodies

  1. Human Monoclonal IL-10 Primary Antibody for ELISA (Capture), FACS - ABIN967464 : Just, Abrams, Louie, Urbano, Wara, Nicholas, Stein, King: Influence of host genotype on progression to acquired immunodeficiency syndrome among children infected with human immunodeficiency virus type 1. in The Journal of pediatrics 1995 (PubMed)
    Show all 8 references for ABIN967464

  2. Cow (Bovine) Polyclonal IL-10 Primary Antibody for IHC, ELISA - ABIN1582204 : Shi, Diez-Freire, Jun, Qi, Katovich, Li, Sriramula, Francis, Sumners, Raizada: Brain microglial cytokines in neurogenic hypertension. in Hypertension 2010 (PubMed)
    Show all 7 references for ABIN1582204

  3. Human Monoclonal IL-10 Primary Antibody for ELISA, IHC - ABIN4324436 : Sahoo, Dey, Maiti: pSiM24 is a novel versatile gene expression vector for transient assays as well as stable expression of foreign genes in plants. in PLoS ONE 2014 (PubMed)
    Show all 6 references for ABIN4324436

  4. Human Polyclonal IL-10 Primary Antibody for IF (p), IHC (p) - ABIN672051 : Kou, Hu, Yao, Wang, Shen, Kang, Hong: Transforming growth factor-?1 promotes Treg commitment in nasal polyposis after intranasal steroid treatment. in Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2013 (PubMed)
    Show all 5 references for ABIN672051

  5. Human Monoclonal IL-10 Primary Antibody for FACS - ABIN4896009 : Schilling, Harasymczuk, Schuler, Egan, Whiteside: IRX-2, a novel biologic, favors the expansion of T effector over T regulatory cells in a human tumor microenvironment model. in Journal of molecular medicine (Berlin, Germany) 2012 (PubMed)
    Show all 3 references for ABIN4896009

  6. Human Polyclonal IL-10 Primary Antibody for EIA, Func - ABIN116099 : Roca, Di Paolo, Petruzzelli, Grandaliano, Ranieri, Schena, Gesualdo: Dexamethasone modulates interleukin-12 production by inducing monocyte chemoattractant protein-1 in human dendritic cells. in Immunology and cell biology 2007 (PubMed)
    Show all 2 references for ABIN116099

  7. Human Polyclonal IL-10 Primary Antibody for EIA, FACS - ABIN952917 : Trajkov, Trajchevska, Arsov, Petlichkovski, Strezova, Efinska-Mladenovska, Sandevski, Spiroski: Association of 22 cytokine gene polymorphisms with tuberculosis in Macedonians. in The Indian journal of tuberculosis 2010 (PubMed)
    Show all 2 references for ABIN952917

  8. Mouse (Murine) Monoclonal IL-10 Primary Antibody for FACS - ABIN118665 : Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. in Immunological reviews 1992 (PubMed)

  9. Human Monoclonal IL-10 Primary Antibody for ELISA, WB - ABIN1724633 : Vieira, de Waal-Malefyt, Dang, Johnson, Kastelein, Fiorentino, deVries, Roncarolo, Mosmann, Moore: Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)

  10. Human Monoclonal IL-10 Primary Antibody for ELISA, WB - ABIN151606 : Rho, Lampe: High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays. in Journal of proteome research 2013 (PubMed)

More Antibodies against IL-10 Interaction Partners

Human Interleukin 10 (IL10) interaction partners

  1. TNF-alpha (show TNF Antibodies) suppresses IL-10 in peripheral B cells via up-regulating Bcl2L12 (show BCL2L12 Antibodies) in patients with ulcerative colitis.

  2. this study shows that IL-10 gene polymorphism is associated with psoriasis in India

  3. association between the interleukin (IL)-10 -592C/A, -819C/T, and -1082G/A genetic variations and susceptibility to diabetic nephropathy in a Chinese population. The IL-10 -592C/A, -819C/T, and -1082G/A polymorphisms were genotyped in diabetic nephropathy patient and control samples. AA genotype of IL-10 -1082G/A significantly increased the susceptibility to diabetic nephropathy. IL-10 -819T/C and -592A/C did not.

  4. We evaluated the relationship between IL-10 gene polymorphisms (-1082A/G and -819T/C) and development of acute pancreatitis in the Chinese population, IL-10 gene polymorphisms at positions -1082A/G and -819T/C were examined. Individuals who carried the AG+GG genotype of IL-10 -1082A/G were associated with greater risk for acute pancreatitis. no significant difference was found at polymorphism at -819T/C.

  5. IL-10 polymorphisms do not influence tacrolimus elimination in lung transplantation patients.

  6. Findings indicate that the CC and AC+CC genotypes of interleukin-10 (IL-10) -592A/C correlate with elevated risk of developing preeclampsia, however, the interleukin-6 (IL-6 (show IL6 Antibodies)) -572G/C, -597G/A, and -174G/C polymorphisms were not found to play a critical role in susceptibility to this disorder.

  7. IL-10 rs1800896 significantly increases the risk of recurrent pregnancy loss, while rs1800872 is not correlated with recurrent pregnancy loss risk. No significant association is demonstrated between rs1800871 and recurrent pregnancy loss risk but this requires further investigation.

  8. this study shows that IL-10 single nucleotide polymorphisms are associated with severity of disease and response to therapy

  9. The study suggests that the IL-10 -819C/T genetic variation may contribute to cervical cancer risk in the Chinese population examined.

  10. Data showed that Actinobacillus (Aggregatibacter) actinomycetemicomitans GroEL protein (show GroEL Antibodies) has an antigenic effect on human primary monocytes. Aa GroEL protein (show GroEL Antibodies) responsive CD14 (show NDUFA2 Antibodies) monocytes stimulates the expression of IL12 (show IL12A Antibodies), IL10, IFNG (show IFNG Antibodies) and TNFalpha (show TNF Antibodies) cytokines with different kinetics and expression profile.

Mouse (Murine) Interleukin 10 (IL10) interaction partners

  1. IL-10 abrogation efficiently induces regulatory T cell (Treg) formation but dampens tumoral neuropilin-1 (Nrp-1 (show NRP1 Antibodies)) Treg signaling, which simultaneously augments Th1 (show HAND1 Antibodies) and Th17 immunity.

  2. After Mycobacterium tuberculosis infection, TNF-alpha (show TNF Antibodies) and IL-10 levels, alveolar macrophage apoptosis, and STAT3 (show STAT3 Antibodies) and p-STAT3 (show STAT3 Antibodies) expression increased significantly on days 1, 3, and 7 (P < 0.05), with maximum values on day 3.

  3. It has been demonstrated that beta-endorphin (show POMC Antibodies) stimulates the zymosan-induced secretion of reactive oxygen species and suppresses the spontaneous production of IL-1beta (show IL1B Antibodies) and IL-10 by murine peritoneal macrophages in vivo.

  4. the degree of fibrosis, inflammatory cell infiltration, and the number of BM-derived myofibroblasts were significantly different between IL-10 KO BM and WT BM transplanted mice, highlighting a likely role of IL-10 in pancreatitis.

  5. CD26 (show DPP4 Antibodies) costimulatory blockade promotes lung allograft acceptance via reduced T cell infiltration, less expression of IL-17 (show IL17A Antibodies), and increased expression of IL-10, likely to be derived from alternatively activated macrophages.

  6. Lactobacillus curvatus WiKim38 induced significantly higher levels of IL-10 in bone marrow-derived dendritic cells.

  7. Light-emitting diode therapy increased the levels of IL-10 in a model of chronic inflammatory hyperalgesia

  8. NAD (+) regulates Treg conversion into Th17 cells and promotes homeostasis through IL-10

  9. Inhibition of Interleukin-10 Signaling Induces Microbiota-dependent Chronic Colitis in Apolipoprotein E (show APOE Antibodies) Deficient Mice.

  10. Melatonin upregulates the expression of IL-10 in the spleen and reduce the severity of experimental autoimmune encephalomyelitis

Cow (Bovine) Interleukin 10 (IL10) interaction partners

  1. This study seems to indicate that PGE2 in cattle does not produce an anti-inflammatory effect by increasing the synthesis of IL-10.

  2. IL-10 mRNA expression increased on day 8 in the mononuclear leukocytes of pregnant cows. In a cell culture experiment, interferon-tau stimulated stimulated IL-10 mRNA expression in mononuclear leukocytes.

  3. Bovine IL-10 potently inhibits the activation of human myeloid cells in response to toll (show TLR4 Antibodies) like receptor activation.

  4. Monocytes obtained from cows with subclinical infection with MAP had upregulated expression of IL-10 and SOCS-3 (show SOCS3 Antibodies), which may have attenuated the capacity of mononuclear phagocytes to initiate inflammatory and adaptive immune responses.

Horse (Equine) Interleukin 10 (IL10) interaction partners

  1. The ability of an EHV-1 isolate to down-regulate IL-10 production might contribute to increased local inflammation and a higher risk for neurological manifestation of the disease after infection with Ab4.

  2. The data suggested in foals there is an impaired Th2 response, the immune response is Th1 (show TH1L Antibodies) biased, interferon-gamma (show IFNG Antibodies) production is qualitatively similar to adult horses, and regulatory IL-10 production by T cells is mature.

  3. serum IL-6 (show IL6 Antibodies):IL-10 ratio is likely to provide a valuable prognosticator for neonatal septicemia

  4. The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6 (show IL6 Antibodies), IL-10 and TNF-alpha (show TNF Antibodies), in horses with recurrent airway obstruction during exacerbation and in remission is reported.

Guinea Pig Interleukin 10 (IL10) interaction partners

  1. The complete open reading frame consists of 537 base pairs which encodes a protein of 179 amino acids. This cDNA sequence exhibited 87% homology with human IL-10.

Rabbit Interleukin 10 (IL10) interaction partners

  1. ICAM1 (show ICAM1 Antibodies) and IL10 were upregulated in ventilator-induced lung injury. Nuclear transcription factor AP-1 (show JUN Antibodies) may be responsible for this upregulation.

Pig (Porcine) Interleukin 10 (IL10) interaction partners

  1. These data indicate that the type 2 porcine reproductive and respiratory syndrome virus N protein plays an important role in IL-10 induction and the N-N non-covalent domain is associated with this activity.

  2. The effects of semen, spermatozoa in extender, or extender alone on the expression of TGF-beta1 (show TGFB1 Antibodies), IL-10, and IL-6 (show IL6 Antibodies) in ovarian follicles are reported.

  3. Prostaglandin E2 potentiates mesenchymal stem cell-induced IL-10+IFN-gamma (show IFNG Antibodies)+CD4 (show CD4 Antibodies)+ regulatory T cells to control transplant arteriosclerosis.

  4. Porcine reproductive and respiratory syndrome virus strain CH-1a could significantly up-regulate IL-10 production through p38 MAPK (show MAPK14 Antibodies) activation.

  5. Boar seminal plasma contained TGF- beta1 (show TGFB1 Antibodies) and IL-10 but with high individual variation.

  6. Changes in interleukin-10 mRNA expression are predictive for 9-day survival of pigs in an emergency preservation and resuscitation model.

  7. These results suggest that TNF-alpha (show TNF Antibodies) and IL-10, but not IL-6 (show IL6 Antibodies), are involved in the late reparatory phases of the experimental disk lesion.

  8. The present study shows that elevated levels of serum CRP (show CRP Antibodies) and IL-10 were associated with porcine circovirus type 2-infected piglets that subsequently developed severe PMWS.(postweaning multisystemic wasting syndrome)

  9. Subclinically porcine circovirus type 2 (PCV2)-infected pigs developed a transient PCV2-specific IL-10 response during the viremic phase of infection which coincided with the inversion of the IgM/IgG ratio.

  10. Twenty one polymorphisms in the IL10 gene have been found, including single nucleotide polymorphisms and insertion deletion polymorphisms. The chromosomal location has been mapped by FISH and radiation hybrid mapping.

Rhesus Monkey Interleukin 10 (IL10) interaction partners

  1. IL-10 produced during the immune response to malaria in this model contributes to suppression of mucosal inflammatory responses to invasive NTS (show NTS Antibodies), which may contribute to differences in the clinical presentation of NTS (show NTS Antibodies) infection in the setting of malaria.

  2. Findings demonstrate that internalization of IL-10R with the resultant impact on IL-10 signaling and dysregulation of the IL-10-mediated anti-inflammatory responses might play a crucial role in epithelial cell damage and subsequent simian immunodeficiency virus pathogenesis.

  3. IL-10 plays a crucial role in maintaining mucosal homeostasis by regulating mucosal IFNgamma and TNFalpha (show TNF Antibodies) cytokine production.

IL-10 (IL10) Antigen Profile

Protein Summary

The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

Gene names and symbols associated with anti-Interleukin 10 (IL10) Antibodies

  • interleukin 10 (IL10) antibody
  • interleukin 10 (Il10) antibody
  • CSIF antibody
  • GVHDS antibody
  • Il-10 antibody
  • IL10A antibody
  • IL10X antibody
  • TGIF antibody

Protein level used designations for anti-Interleukin 10 (IL10) Antibodies

T-cell growth inhibitory factor , cytokine synthesis inhibitory factor , interleukin-10 , CSIF , IL-10 , uncharacterized protein LOC100715618 , Cytokine synthesis inhibitory factor , Interleukin-10

3586 Homo sapiens
16153 Mus musculus
25325 Rattus norvegicus
281246 Bos taurus
100034187 Equus caballus
443342 Ovis aries
403628 Canis lupus familiaris
428264 Gallus gallus
100860746 Capra hircus
100715618 Cavia porcellus
100008701 Oryctolagus cuniculus
397106 Sus scrofa
493683 Felis catus
694931 Macaca mulatta
100386149 Callithrix jacchus
469657 Pan troglodytes
101271889 Orcinus orca
Selected quality suppliers for anti-IL-10 (IL10) Antibodies
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