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The protein encoded by IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. Additionally we are shipping IL-10 Kits (288) and IL-10 Proteins (172) and many more products for this protein.
Showing 10 out of 630 products:
Human Monoclonal IL-10 Primary Antibody for FACS - ABIN1107781
Moore, Zaki: Clinical cytokine network cytometry. in Clinics in laboratory medicine 2001
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Human Monoclonal IL-10 Primary Antibody for FACS - ABIN1107780
Santiago, Luca, Bertho, Azeredo-Coutinho, Coutinho: Detection of intracytoplasmic cytokines by flow cytometry. in Memórias do Instituto Oswaldo Cruz 2000
Show all 9 references for ABIN1107780
Human Monoclonal IL-10 Primary Antibody for ELISA (Capture), FACS - ABIN967464
Just, Abrams, Louie, Urbano, Wara, Nicholas, Stein, King: Influence of host genotype on progression to acquired immunodeficiency syndrome among children infected with human immunodeficiency virus type 1. in The Journal of pediatrics 1995
Show all 8 references for ABIN967464
Cow (Bovine) Polyclonal IL-10 Primary Antibody for IHC, ELISA - ABIN1582204
Shi, Diez-Freire, Jun, Qi, Katovich, Li, Sriramula, Francis, Sumners, Raizada: Brain microglial cytokines in neurogenic hypertension. in Hypertension 2010
Show all 7 references for ABIN1582204
Human Polyclonal IL-10 Primary Antibody for IF (p), IHC (p) - ABIN672051
Kou, Hu, Yao, Wang, Shen, Kang, Hong: Transforming growth factor-?1 promotes Treg commitment in nasal polyposis after intranasal steroid treatment. in Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2013
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Human Polyclonal IL-10 Primary Antibody for EIA, Func - ABIN116099
Roca, Di Paolo, Petruzzelli, Grandaliano, Ranieri, Schena, Gesualdo: Dexamethasone modulates interleukin-12 production by inducing monocyte chemoattractant protein-1 in human dendritic cells. in Immunology and cell biology 2007
Show all 2 references for ABIN116099
Human Polyclonal IL-10 Primary Antibody for EIA, FACS - ABIN952917
Trajkov, Trajchevska, Arsov, Petlichkovski, Strezova, Efinska-Mladenovska, Sandevski, Spiroski: Association of 22 cytokine gene polymorphisms with tuberculosis in Macedonians. in The Indian journal of tuberculosis 2010
Show all 2 references for ABIN952917
Human Polyclonal IL-10 Primary Antibody for IP, Neut - ABIN1043703
Said, Dupuy, Trautmann, Zhang, Shi, El-Far, Hill, Noto, Ancuta, Peretz, Fonseca, Van Grevenynghe, Boulassel, Bruneau, Shoukry, Routy, Douek, Haddad, Sekaly: Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection. in Nature medicine 2010
Human Monoclonal IL-10 Primary Antibody for ELISA, WB - ABIN1724633
Vieira, de Waal-Malefyt, Dang, Johnson, Kastelein, Fiorentino, deVries, Roncarolo, Mosmann, Moore: Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI. in Proceedings of the National Academy of Sciences of the United States of America 1991
Mouse (Murine) Monoclonal IL-10 Primary Antibody for FACS - ABIN118665
Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. in Immunological reviews 1992
a protective role of mutant alleles G and A in IL-10-1082A/G and IL-13 (show IL13 Antibodies)+2044G/A against gliomas.
The data indicate that IL-10 polymorphism G-1082A may be involved in the pathogenesis of chronic lymphoid leukemia.
Specific IL-10 variants (rs3024490, rs1800872, and rs1800871) and haplotype (GTCCA and TGATG) may contribute to the development of cervical cancer among Tunisian women
Data show that the high intensity interval exercise (HIIE) induced decrease in interleukin-8 (IL-8 (show IL8 Antibodies)) levels 30min post session and a progressive elevation in interleukin-10 (IL-10) levels immediately and 30min post in lean and overweight-obese.
Patients with gastric cancer (GC) have significantly higher IL-6 (show IL6 Antibodies) levels, and lower IL-8 (show IL8 Antibodies) and IL-10 concentrations, in comparison to controls and patients with other gastric neoplasms
the results of our study suggested an association between the IL-10- 1082A/G gene polymorphisms and an elevated risk of coronary artery disease
IL-10 rs1800896 was correlated with an increased risk of acute pancreatitis in codominant, dominant, and recessive models.
Analysis of peripheral leucocytes, eosinophils, immunoglobulin E, and IL-4 (show IL4 Antibodies) and IL-10 concentrations presented significantly higher values in children with radiologically confirmed liver granuloma than in uncomplicated hepatomegaly.
Patients with occupational allergic dermatoses showed significantly higher frequency of polymorphic variants of cytokine genes IL4 (show IL4 Antibodies) C589T, IL10 C819T, IL10 G1082A, IL10 C592A, and TNF (show TNF Antibodies) G308A in comparison with the population control.
IL-10 -592A/C (rs1800872) polymorphism was associated with an increased risk of early-onset preeclampsia in a Chinese population
IFN-gamma (show IFNG Antibodies)-treated mesenchymal stem cells strongly inhibit IL-10 production by activated B cells by a mechanism requiring cell contact and involving the Cox-2 (show COX2 Antibodies) pathway.
results suggest that CDK5 (show CDK5 Antibodies) enhances the inflammatory function of macrophages by inhibiting the MAPK (show MAPK1 Antibodies)-dependent production of IL-10.
The relative severity of T. muris infection in IL-10 knockout mice that were treated with metronidazole, prednisolone, or IL-10 is reported.
Studied DC-specific TLR4 (show TLR4 Antibodies) signaling on host defense against intra-abdominal polymicrobial sepsis; found TLR4 (show TLR4 Antibodies) deletion on DCs was associated with lower levels of IL-10, higher PMN (show TBCE Antibodies) accumulation in the peritoneal cavity, and higher expression of CXCR2 (show CXCR2 Antibodies).
IL-10 is critical to restraining autoantibody production and surprisingly plays a vital role in supporting the expansion of innate-like populations.
A rare but potent B-cell subset in both humans and mice is capable of inhibiting immune responses through the production of the anti-inflammatory cytokine IL-10. (Review)
Identify a specific LN-derived B2-B(reg (show KCNH2 Antibodies)) subset that confers IL-10 mediated protection from neointima formation.
Il10(-/-) Treg cells showed reduced steady-state Foxp3 (show FOXP3 Antibodies) expression, and polyclonal stimulation caused greater loss of Foxp3 (show FOXP3 Antibodies)
This study represents the first experimental characterization of the IL-10.GAG complex structure and provides the starting point for revealing the biological significance of the interaction of IL-10 with GAGs.
IL-10 counteracts both the pressoric activity of Ang II (show AGT Antibodies) as well as vascular dysfunction associated with hypertension, partially, modulating the RhoA (show RHOA Antibodies)-Rho kinase (show ROCK2 Antibodies) pathway.
This study seems to indicate that PGE2 in cattle does not produce an anti-inflammatory effect by increasing the synthesis of IL-10.
IL-10 mRNA expression increased on day 8 in the mononuclear leukocytes of pregnant cows. In a cell culture experiment, interferon-tau stimulated stimulated IL-10 mRNA expression in mononuclear leukocytes.
Bovine IL-10 potently inhibits the activation of human myeloid cells in response to toll (show TLR4 Antibodies) like receptor activation.
Monocytes obtained from cows with subclinical infection with MAP had upregulated expression of IL-10 and SOCS-3 (show SOCS3 Antibodies), which may have attenuated the capacity of mononuclear phagocytes to initiate inflammatory and adaptive immune responses.
The ability of an EHV-1 isolate to down-regulate IL-10 production might contribute to increased local inflammation and a higher risk for neurological manifestation of the disease after infection with Ab4.
The data suggested in foals there is an impaired Th2 response, the immune response is Th1 (show TH1L Antibodies) biased, interferon-gamma (show IFNG Antibodies) production is qualitatively similar to adult horses, and regulatory IL-10 production by T cells is mature.
serum IL-6 (show IL6 Antibodies):IL-10 ratio is likely to provide a valuable prognosticator for neonatal septicemia
The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6 (show IL6 Antibodies), IL-10 and TNF-alpha (show TNF Antibodies), in horses with recurrent airway obstruction during exacerbation and in remission is reported.
ICAM1 (show ICAM1 Antibodies) and IL10 were upregulated in ventilator-induced lung injury. Nuclear transcription factor AP-1 (show JUN Antibodies) may be responsible for this upregulation.
These data indicate that the type 2 porcine reproductive and respiratory syndrome virus N protein plays an important role in IL-10 induction and the N-N non-covalent domain is associated with this activity.
The effects of semen, spermatozoa in extender, or extender alone on the expression of TGF-beta1 (show TGFB1 Antibodies), IL-10, and IL-6 (show IL6 Antibodies) in ovarian follicles are reported.
Prostaglandin E2 potentiates mesenchymal stem cell-induced IL-10+IFN-gamma (show IFNG Antibodies)+CD4 (show CD4 Antibodies)+ regulatory T cells to control transplant arteriosclerosis.
Porcine reproductive and respiratory syndrome virus strain CH-1a could significantly up-regulate IL-10 production through p38 MAPK (show MAPK14 Antibodies) activation.
Boar seminal plasma contained TGF- beta1 (show TGFB1 Antibodies) and IL-10 but with high individual variation.
Changes in interleukin-10 mRNA expression are predictive for 9-day survival of pigs in an emergency preservation and resuscitation model.
These results suggest that TNF-alpha (show TNF Antibodies) and IL-10, but not IL-6 (show IL6 Antibodies), are involved in the late reparatory phases of the experimental disk lesion.
The present study shows that elevated levels of serum CRP (show CRP Antibodies) and IL-10 were associated with porcine circovirus type 2-infected piglets that subsequently developed severe PMWS.(postweaning multisystemic wasting syndrome)
Subclinically porcine circovirus type 2 (PCV2)-infected pigs developed a transient PCV2-specific IL-10 response during the viremic phase of infection which coincided with the inversion of the IgM/IgG ratio.
Twenty one polymorphisms in the IL10 gene have been found, including single nucleotide polymorphisms and insertion deletion polymorphisms. The chromosomal location has been mapped by FISH and radiation hybrid mapping.
IL-10 produced during the immune response to malaria in this model contributes to suppression of mucosal inflammatory responses to invasive NTS (show NTS Antibodies), which may contribute to differences in the clinical presentation of NTS (show NTS Antibodies) infection in the setting of malaria.
Findings demonstrate that internalization of IL-10R with the resultant impact on IL-10 signaling and dysregulation of the IL-10-mediated anti-inflammatory responses might play a crucial role in epithelial cell damage and subsequent simian immunodeficiency virus pathogenesis.
IL-10 plays a crucial role in maintaining mucosal homeostasis by regulating mucosal IFNgamma and TNFalpha (show TNF Antibodies) cytokine production.
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.
T-cell growth inhibitory factor
, cytokine synthesis inhibitory factor
, uncharacterized protein LOC100715618
, Cytokine synthesis inhibitory factor