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Interleukin 6 (IL6) ELISA Kits

Cytokine with a wide variety of biological functions.

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More ELISA Kits for Interleukin 6 Interaction Partners

Mouse (Murine) Interleukin 6 (IL6) interaction partners

  1. Blocking IL-6 trans-signaling in the CNS abrogates the ability of IL-6 to suppress feeding. Furthermore, gp130 (show LRPPRC ELISA Kits) expression is enhanced in the paraventricular nucleus of the hypothalamus (PVH) of obese mice, and deletion of gp130 (show LRPPRC ELISA Kits) in the PVH attenuates the beneficial central IL-6 effects on metabolism

  2. We conclude that upon ligand binding, TLR4 (show TLR4 ELISA Kits) activates PI3K/Akt (show AKT1 ELISA Kits) signaling to induce F-spondin (show SPON1 ELISA Kits) expression, subsequently control CREB (show CREB1 ELISA Kits)-mediated IL-6 production to promote VSMC migration. These findings provide vital insights into the essential role of F-spondin (show SPON1 ELISA Kits) in VSMC function and will be valuable for developing new therapeutic strategies against atherosclerosis.

  3. The mechanosensitive up-regulation and release of cytokine IL-6 from the retina involves the P2X7 receptor (show P2RX7 ELISA Kits), with both astrocytes and neurons contributing to the response

  4. his study shows that Mir (show MLXIP ELISA Kits)-26a attenuates the development of non-alcoholic fatty liver disease by inhibiting the expression of IL-17 (show IL17A ELISA Kits) and IL-6

  5. These results strongly suggest that incretins upregulate the TNF-alpha-stimulated IL6 synthesis in osteoblasts, and that the amplifying effect of incretin is exerted via reducing the IkappaB/NFkappaB pathway through the adenylyl cyclase-cAMP system.

  6. Genetic deletion of IL-6 attenuates left ventricle hypertrophy and dysfunction.

  7. In this study we have demonstrated that IL-6 is one of the mediating factors that contributes to the development of cardiac infarct size during the early period (<1 (show PER1 ELISA Kits) day) of reperfusion, following an injurious period of cardiac ischemia in the absence of surgical stress

  8. this study shows that downregulation of IL-6 in dendritic cells by paeoniflorin is mediated via upregulation of Socs3 (show SOCS3 ELISA Kits)

  9. provided evidences that IL-6 over-secretion impaired osteogenesis of osteoporotic bone marrow stromal cells

  10. Because the inhibitor of Toll-like receptor 4 (show TLR4 ELISA Kits) blocks the BP1-induced secretion of TNF-alpha (show TNF ELISA Kits) and IL-6, we hypothesize that alpha-glucan BP1 activates TLR4 (show TLR4 ELISA Kits), which mediates the above-mentioned immunomodulating effects.

Human Interleukin 6 (IL6) interaction partners

  1. MALAT1 suppressed LPS (show IRF6 ELISA Kits)-induced mRNA accumulation of TNFa (show TNF ELISA Kits) and IL-6 without suppressing IL-1beta (show IL1B ELISA Kits) mRNA production. abnormal expression of MALAT1 was found to be NF-kappaB (show NFKB1 ELISA Kits)-dependent

  2. Taken together, these findings suggested that E2 inhibited the proliferation of AR HCC (show FAM126A ELISA Kits) cells through down-regulation of IL-6/STAT3 (show STAT3 ELISA Kits) signaling. Thus, E2 can be a potential therapeutic drug for treatment of metastatic or chemo-resistant HCC (show FAM126A ELISA Kits).

  3. IL-6 (-174) G/C polymorphism and serum IL-6 levels may be associated with the severity of NTG (show OPA1 ELISA Kits)

  4. High IL-6 expression is associated with obesity.

  5. Our results showed that 3 single nucleotide polymorphisms of ACE rs4340, IL-6 rs1800795, and NOS3 rs1799983 were significantly associated with the risks of mycoplasma pneumoniae pneumonia (MPP), while no differences were observed in genotype frequencies of GSTM1 and CYP1A1. The combinations of ACE/NOS3/CYP1A1 and ACE /NOS3 contribute to the genetic susceptibility of MPP in Chinese children.

  6. PCT (show UROD ELISA Kits) may be considered a good predictor of adverse renal outcome in cardiac surgery patients, whereas IL-6 seems to possess a good predictive value for mortality in this population of patients.

  7. sEng treatment resulted in an activation of NF-kappaB (show NFKB1 ELISA Kits), IL-6, suggesting activation of pro-inflammatory phenotype in endothelial cells.

  8. Ninj1 (show NINJ1 ELISA Kits) suppresses migration, invasion and metastasis of lung cancer via inhibition of the IL-6 signaling pathway in vitro and in vivo.

  9. The meta-analysis found that rs1800795 SNP of IL-6 gene is not significantly associated with susceptibility to arterial thromboembolic events (C allele vs. G allele, OR=1.04, 95% CI=0.91-1.19, P=0.619; CC vs. CG+GG, OR=1.09, 95% CI=0.91-1.31, P=0.364; CC+CG vs. GG, OR=0.97, 95% CI=0.78-1.21, P=0.763, respectively), the SNP of IL-6 gene did not show any significant association with ischemic stroke or myocardial infarction

  10. High IL-6 expression is associated with metabolic syndrome.

Cow (Bovine) Interleukin 6 (IL6) interaction partners

  1. when a confluent endometrial epithelial cell barrier is faced with infection and damage, chemokines attract immune cells to the uterine lumen, but IL6 is solely secreted apically to ensure immune cells are only exposed to IL6 once they reach the lumen.

  2. The results revealed that the peak expression of IL6 and 21 was on DPV 28 which correlated well with the FMDV antibody titer and plummeted to the prevaccination titer level by 60 DPV.

  3. Exposure to follicular fluid transiently increased the transcript levels of IL8 (show IL8 ELISA Kits) and PTGS2 (show PTGS2 ELISA Kits), and decreased the expression of SOD2 (show SOD2 ELISA Kits), GPX3 (show GPX3 ELISA Kits), DAB2 (show DAB2 ELISA Kits), and NR3C1 (show NR3C1 ELISA Kits). TNF (show TNF ELISA Kits) and IL6 levels were also decreased while those of NAMPT (show NAMPT ELISA Kits) were unaffected.

  4. Testicular IL-1 alpha (show IL1A ELISA Kits) and IL-1 beta (show IL1B ELISA Kits) concentrations were highest in the early post-natal period; however, IL-1 (show IL1A ELISA Kits) bioactivity and IL-6 concentrations were greatest in the immediate pre-pubertal period.

  5. The results showed that the expression of TNF-alpha (show TNF ELISA Kits), iNOS (show NOS2 ELISA Kits), and IL-6 in alveolar macrophages was up-regulated by stimulation with the recombinant Mce4A protein of M. bovis; in contrast, expression of IL-12 (show IL12A ELISA Kits) was unaffected.[IL-6, IL-12 (show IL12A ELISA Kits)]

  6. results show for the first time that interleukin-6 (IL6), in the presence of its soluble receptor (show IFNAR1 ELISA Kits) (sIL (show STIL ELISA Kits)-6R), induces activation of JAK1 (show JAK1 ELISA Kits), JAK2 (show JAK2 ELISA Kits), and STAT1 (show STAT1 ELISA Kits)/STAT3 (show STAT3 ELISA Kits) proteins in bovine articular chondrocytes.

  7. Mechanical injury potentiates the catabolic effects of TNFalpha (show TNF ELISA Kits) and IL-6/sIL (show STIL ELISA Kits)-6R in causing proteoglycan (show Vcan ELISA Kits) degradation in human and bovine cartilage.

Rabbit Interleukin 6 (IL6) interaction partners

  1. Mild heat shock increased the production of inflammatory cytokines, IL-1beta (show IL1B ELISA Kits) and IL-6 in rabbit cornea cells.

Pig (Porcine) Interleukin 6 (IL6) interaction partners

  1. we showed that IL-6 did not directly promote the proliferation of theca interna cells.

  2. Induction of ischemic osteonecrosis results in IL-6 production in the articular cartilage through an HIF-1 (show HIF1A ELISA Kits)-dependent pathway. IL-6 produced by hypoxic articular chondrocytes stimulates inflammatory cytokine responses in synovial cells.

  3. The effects of semen, spermatozoa in extender, or extender alone on the expression of TGF-beta1 (show TGFB1 ELISA Kits), IL-10 (show IL10 ELISA Kits), and IL-6 in ovarian follicles are reported.

  4. Data suggest IL6 prevents apoptosis in blastocysts (here, parthenotes) and enhances blastocyst viability via IL6/STAT3 (show STAT3 ELISA Kits) (signal transducer/activator of transcription (show STAT1 ELISA Kits) 3) signaling pathway (including up-regulation of STAT3 (show STAT3 ELISA Kits) expression/phosphorylation).

  5. LIF (show LIF ELISA Kits) and IL-6 are important components of embryo-uterine interactions during early pregnancy in the pig, and may contribute to successful conceptus implantation.

  6. INFgamma and IL-6 modulate PPARs gene expression in the porcine endometrium during the estrous cycle and pregnancy.

  7. interleukin-6, endothelin ET-1 (show EDN1 ELISA Kits), and apoptotic Bak (show BAK1 ELISA Kits) and Bcl-XL (show BCL2L1 ELISA Kits) genes have roles in small bowel transplantation, in a swine model of ischemia and reperfusion injury

  8. Data show that all five molecules, BNP, ICAM-1 (show ICAM1 ELISA Kits), TNF-alpha (show TNF ELISA Kits), VCAM-1 (show VCAM1 ELISA Kits) and IL-6, quickly and reliably signaled adverse interactions.

  9. IL-6 level from frozen peripheral blood mononuclear cells was significantly lower than that from fresh ones.

  10. These results suggest that TNF-alpha (show TNF ELISA Kits) and IL-10 (show IL10 ELISA Kits), but not IL-6, are involved in the late reparatory phases of the experimental disk lesion.

Goat Interleukin 6 (IL6) interaction partners

  1. Plasma nitric oxide acts as a regulator of cytokine function exhibiting negative feedback to maintain steady plasma IL-6 concentration in protein- or energy-restricted goats during late gestation.

Horse (Equine) Interleukin 6 (IL6) interaction partners

  1. These data suggest that IL-6 may play a key role in equine metabolic syndrome (EMS), and that pro-inflammatory cytokines levels in serum may serve as an additional tool for diagnosing EMS.

  2. IL-6 stimulation decreased chondrocyte expression of the canonical Wnt (show WNT2 ELISA Kits) signaling pathway transactivator beta-catenin (show CTNNB1 ELISA Kits), induced expression of inhibitors of the Wnt (show WNT2 ELISA Kits) pathway, and increased expression of GDF-5 (show GDF5 ELISA Kits).

  3. study shows that IL-6 is rapidly induced in BAL-cells of airway-compromised horses in response to adenosine exposure, probably through A2BAR (show ADORA2B ELISA Kits) activation and that this effect can be modulated by A2AAR (show ADORA2A ELISA Kits)

  4. Our data show the presence of a polymorphism downstream of the equine IL-6 gene that is associated with the basal Cu:Zn ratio in horses independent of breed.

  5. Expression levels of IL-6 are significantly increased in peripheral blood mononuclear cells from trained horses compared to sedentary animals.

  6. Failure of passive transfer may directly influence the serum IL-6 concentration in septic foals. Neither serum IL-6 nor IL-10 (show IL10 ELISA Kits) alone, were useful diagnostic indices of sepsis in equine neonates.

  7. The contribution of bronchial epithelium to airway inflammation, with focus on mRNA and protein expression of IL-6, IL-10 (show IL10 ELISA Kits) and TNF-alpha (show TNF ELISA Kits), in horses with recurrent airway obstruction during exacerbation and in remission is reported.

Rainbow Trout (Oncorhynchus mykiss) Interleukin 6 (IL6) interaction partners

  1. IL6 mRNA abundance was significantly increased in spleen, liver, and gill of rainbow trout after experimental infection with Aeromonas salmonicida.

  2. in this paper we present for the first time in fish the functional characterisation of IL-6, using rainbow trout

  3. found that peptidoglycans derived from Gram-negative bacteria (Escherichia coli 0111:B4 and K12 (show KRT12 ELISA Kits)), are potent inducers of IL-1beta (show IL1B ELISA Kits) and IL-6 gene expression and were equal to, or more potent than, crude LPS (show IRF6 ELISA Kits).

Interleukin 6 (IL6) Antigen Profile

Antigen Summary

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity).

Gene names and symbols associated with Interleukin 6 (IL6) ELISA Kits

  • interleukin-6 (il-6) antibody
  • il6 antibody
503562 Takifugu rubripes
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