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The protein encoded by KISS1R is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. Additionally we are shipping KISS1R Kits (13) and and many more products for this protein.
Showing 10 out of 96 products:
Human Polyclonal KISS1R Primary Antibody for IF (p), IHC (p) - ABIN741180
Luo, Li, Li, Zhang, Zhang: Leptin/leptinR-kisspeptin/kiss1r-GnRH pathway reacting to regulate puberty onset during negative energy balance. in Life sciences 2016
Show all 2 references for ABIN741180
Bat Polyclonal KISS1R Primary Antibody for IHC (p) - ABIN270735
Cartwright, Williams: Altered placental expression of kisspeptin and its receptor in pre-eclampsia. in The Journal of endocrinology 2012
Show all 2 references for ABIN270735
Human Polyclonal KISS1R Primary Antibody for IF, ELISA - ABIN1535762
Ohtaki, Shintani, Honda, Matsumoto, Hori, Kanehashi, Terao, Kumano, Takatsu, Masuda, Ishibashi, Watanabe, Asada, Yamada, Suenaga, Kitada, Usuki, Kurokawa, Onda, Nishimura, Fujino: Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor. in Nature 2001
duplicated kiss1r genes evolved a distinct gene expression pattern, different ligand selectivity, and novel nuclear isoforms. While a single kiss1ra mRNA was detected exclusively in the brain, 5 kiss1rb transcripts were found in many peripheral tissues.
The only site of expression of kiss1r mRNA cells was the ventromedial habenula, showing an expression pattern very similar to that of the kiss1 (show KISS1 Antibodies) mRNA or proKiss1 peptide.
Zebrafish kiss1r was expressed predominantly in the brain, with a minor level of expression in the eye.
Kiss1 (show KISS1 Antibodies)/Kiss1r system may participate in puberty initiation in fish as well.
In hu (show KISS1 Antibodies)man cumulus GCs, kiss1r mRNA levels were positively correlated with age but not with BMI. There was no expression of kiss1 mRNA in either (show KISS1 Antibodies) cumulus or mural GCs
KISS1R signaling induces invadopodia formation and activation of key invadopodia proteins, cortactin (show CTTN Antibodies), cofilin (show CFL1 Antibodies) and membrane type I matrix metalloproteases (MT1-MMP (show MMP14 Antibodies)).
KISS1R Low Expression Correlates with Colorectal Liver Metastasis.
KiSS1 (show KISS1 Antibodies) is a metastasis suppressor gene of pancreatic cancer, and this suppression is not dependent on the expression levels of GPR54.
confirmed that mutations in KISS1 (show KISS1 Antibodies) and KISS1R are not a common cause for ICPP
Effects of systematic N-terminus deletions and benzoylations of endogenous RF-amide peptides on NPFF1R, NPFF2R, GPR10 (show PRLHR Antibodies), GPR54 and GPR103 (show QRFPR Antibodies).
Two novel heterozygous missense mutations in FGFR1 (show FGFR1 Antibodies) and one novel heterozygous missense mutation in KISS1R, were identified in in Chinese Kallmann Syndrome Males with Cleft Lip/Palate.
The majority of human non-functioning pituitary tumors expressed KISS1R with lower rates of expression in other types of pituitary tumors.
The promoter of GPR54 is unmethylated in normal endometrium
Present data do not confirm the protective role of KiSS1 (show KISS1 Antibodies)/KiSS1R in breast cancer progression, but our results do support the hypothesis that KiSS1 (show KISS1 Antibodies)/KiSS1R system is activated even in primary breast cancer and sustained during invasion to local lymph nodes.
kiss1 (show KISS1 Antibodies) and kiss1r mRNA levels were significantly higher in old compared to reproductive-aged mice, and diet-induced obesity did not alter kiss1 (show KISS1 Antibodies) or kiss1r mRNA levels. Compared to young control mice, young MCP-1 (show CPT1B Antibodies) knockout mice had significantly lower ovarian kiss1 (show KISS1 Antibodies) mRNA
On D4 of pregnancy, the mouse uterus expresses a functional kisspeptin/KISS1R signaling system.
Gnaq (show GNAQ Antibodies) was selectively inactivated in GnRH (show GNRH1 Antibodies) neurons of global Gna11 (show GNA11 Antibodies)--null mice, but they still responded to kisspeptin, confirming that KISS1R signals via non-Galphaq (show GNAQ Antibodies)/11-coupled pathways.
orchestrated onset of kisspeptin and GPR54 expression in the male embryonic brain at embryonic day 13.5
Results demonstrate defective negative feedback in global Gpr54-null mice that cannot be attributed to a lack of prior exposure of the gonadotropin-releasing hormone neuronal network to cyclical estradiol
Expression of Kiss1 (show KISS1 Antibodies) and Gpr54 was confirmed in mouse placenta but no differences in birth weight were found in mice that had been supported by a mutant placenta during fetal development.
Kiss1 (show KISS1 Antibodies)/GPR54 system is involved in promoting uterine decidualization during early pregnancy in mice
Kiss1r in GnRH neurons is critical for reproductive development and fertility.
kisspeptin-1 (show KISS1 Antibodies) and Kiss1r signaling influences BW, energy expenditure, and glucose homeostasis in a sexually dimorphic and partially sex steroid-independent manner
kisspeptin receptor (Kiss1r), a GPCR that is activated by kisspeptin to regulate the onset of puberty and adult reproductive function, is enriched in cilia projecting from mouse
The KISS1R gene is mapped and mutations within the gene are determined not to be responsible for divergent age at puberty.
The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty.
G protein-coupled receptor 54
, KISS1 receptor like
, kisspeptin receptor 2
, KiSS-1 receptor
, kisspeptins receptor
, G-protein coupled receptor OT7T175
, kiSS-1 receptor
, metastin receptor
, G-protein coupled receptor 54
, orphan G protein-coupled receptor 54
, orphan G protein-coupled receptor GPR54