KISS1R antibody (AA 235-263)

Catalog No. ABIN1881480

The Rabbit Polyclonal anti-KISS1R antibody (Clone RB40407) (ABIN1881480) specifically detects KISS1R in WB. The antibody is reactive with Human samples.

Quick Overview for KISS1R antibody (AA 235-263) (ABIN1881480)

Target: KISS1R (KISS1 Receptor (KISS1R))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KISS1R antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB40407

Product Details anti-KISS1R Antibody

Binding Specificity: AA 235-263

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KISS1R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-263 amino acids from the Central region of human KISS1R.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for KISS1R

Target: KISS1R (KISS1 Receptor (KISS1R))

Alternative Name: KISS1R

Background: Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.

Molecular Weight: 42586

NCBI Accession: NP_115940

UniProt: Q969F8