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a transcription factor that works with Sp1 to activate the Laminin gamma1 chain gene [RGD, Feb 2006].. Additionally we are shipping KLF4 Antibodies (231) and KLF4 Proteins (17) and many more products for this protein.
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Human KLF4 ELISA Kit for Sandwich ELISA - ABIN416925
Seipel, Marques, Bozzini, Meinken, Mueller, Pabst: Inactivation of the p53-KLF4-CEBPA Axis in Acute Myeloid Leukemia. in Clinical cancer research : an official journal of the American Association for Cancer Research 2016
zebrafih Klf4a is essential for the repression of intestinal cell proliferation
Proper heart valve formation in zebrafish critically depends on protein kinase D2 (show PKD2 ELISA Kits)-histone deacetylase 5 (show HDAC5 ELISA Kits)-Kruppel-like factor signaling.
these are the first two cases reported of the simultaneous occurrence of secretory meningiomas with mutation of KLF4 in collision with a glioblastoma and an anaplastic astrocytoma, respectively
KLF4-regulated drug resistance might, at least partially, positively regulate high-mobility group box 1 (HMGB1 (show HMGB1 ELISA Kits)), which is a significant contributor to chemoresistance in osteosarcoma cells
Authors demonstrate that F-box only protein 22 (FBXO22 (show FBXO22 ELISA Kits)) interacts with and thereby destabilizes KLF4 via polyubiquitination. As a result, FBXO22 (show FBXO22 ELISA Kits) could promote HCC (show FAM126A ELISA Kits) cells proliferation.
Angiotensin II can modulate epigenetic regulation in podocytes and renin (show REN ELISA Kits)-angiotensin blockade inhibits these actions in part via KLF4 in proteinuric kidney diseases.
Arginine methylation of KLF4 by PRMT5 (show PRMT5 ELISA Kits) inhibits KLF4 ubiquitylation by VHL (show VHL ELISA Kits) and thereby reduces KLF4 turnover.
Decreased KLF4 expression mediates antileukemic effects through regulation of gene and microRNA networks, containing miR (show MLXIP ELISA Kits)-150, CDKN1A, and MYC (show MYC ELISA Kits).
Kruppel-Like Factor 4 Overexpression Initiates a Mesenchymal-to-Epithelial Transition and Redifferentiation of Human Pancreatic Cells following Expansion in Long Term Adherent Culture
our study reveals that Ang II (show AGT ELISA Kits) downregulates miR (show MLXIP ELISA Kits)-145 to regulate Klf4 and myocardin (show MYOCD ELISA Kits) expression in HCASMCs under high glucose conditions. Ang II (show AGT ELISA Kits) plays a critical role in the regulation of miR (show MLXIP ELISA Kits)-145 under hyperglycemic conditions
Expression of KLF4 in mononuclear leukocytes positively correlates with cellular markers of immune activation, whereas KLF2 (show KLF2 ELISA Kits) expression negatively correlates with markers of subclinical atherosclerosis in this HIV-infected population.
Data show that 1-acylglycerol-3-phosphate O-acyltransferase 9 (AGPAT9 (show AGPAT9 ELISA Kits)) inhibit cell growth by regulating expression of KLF4/LASS2 (show CERS2 ELISA Kits)/V-ATPase (show ATP6V1H ELISA Kits) proteins in breast cancer.
Klf4 is transcribed both maternally and zygotically and the transcript is ubiquitous in embryos during germ-layer formation
Authors show that absence of Klf4 accelerates carcinogenesis and correlates with the absence of cytokeratin 1 (show KRT1 ELISA Kits) expression. Results suggest a potential role for KLF4 as a tumor suppressor gene for the tongue epithelium.
KLF-4 was downregulated in the TGF-beta (show TGFB1 ELISA Kits)-induced EMT (show ITK ELISA Kits) model in LA-4 cells. KLF-4 overexpression markedly reduced the PAI-1 (show SERPINE1 ELISA Kits) expression and inhibited the TGF-beta (show TGFB1 ELISA Kits)-induced EMT (show ITK ELISA Kits) .
Data show that CCAAT-enhancer-binding protein-alpha (C/EBPalpha (show CEBPA ELISA Kits)) directly regulates Kruppel-like factor 4 (Klf4) expression and increasing the levels of histone demethylase (show MBD2 ELISA Kits) Lsd1 (show KDM1A ELISA Kits) and transcription factor Brd4 (show BRD4 ELISA Kits) in B cell.
Data indicate that miR (show MLXIP ELISA Kits)-25 is a novel negative regulator of adipocyte differentiation and it suppressed 3T3-L1 adipogenesis by targeting KLF4 and C/EBPalpha (show CEBPA ELISA Kits), which provides novel insights into the molecular mechanism of miRNA-mediated cellular differentiation.
transcriptional cooperation between GR and Klf4 may determine cell-type specific gene expression regulation
unravels a novel mechanism how matrix stiffness regulates cellular proliferation and highlights the importance of matrix stiffness-modulated Klf5 (show KLF5 ELISA Kits)/Klf4 in the regulation of renal physiologic functions and fibrosis progression
endothelial-specific loss of Mekk3 (show MAP3K3 ELISA Kits), Klf2 (show KLF2 ELISA Kits) or Klf4 markedly prevents cerebral cavernous malformation lesion formation, reverses the increase in Rho activity, and rescues lethality
positively regulates Pax6 (show PAX6 ELISA Kits) expression and proliferation of neuronal progenitors in the rhombic lip, external granular layer and neuroepithelium
The role of KLF4 on autophagy in mouse embryonic fibroblasts, was investigated.
miR (show MYLIP ELISA Kits)-92a coregulates KLF4 and KLF2 (show KLF2 ELISA Kits) expression in arterial endothelium and contributes to phenotype heterogeneity associated with regional atherosusceptibility and protection in vivo.
a transcription factor that works with Sp1 to activate the Laminin gamma1 chain gene
Krueppel-like factor 4
, Kruppel-like transcription factor 4a
, Kruppel-like factor 4 (gut)
, Kruppel-like factor 4
, endothelial Kruppel-like zinc finger protein
, epithelial zinc finger protein EZF
, gut-enriched krueppel-like factor
, Kruppel-like transcription factor
, blood island enriched kruppel like factor
, Kruppel-like factor 4 (Gut enriched kruppel-like factor) (Epithelial zinc-finger protein EZF)