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catalyzes the hydrolysis of pyridoxine-5'-beta-D-glucoside to release pyridoxine\; also catalyses the hydrolysis of lactose to D-glucose and D-galactose [RGD, Feb 2006].. Additionally we are shipping Lactase Antibodies (51) and Lactase Kits (9) and many more products for this protein.
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The polymorphisms in 5' flanking region and enhancer influenced the expression of LCT.
AA sequence data for pyridoxine-5'-beta-D-glucoside hydrolase & results of Northern blot analyses suggest a common origin for it and lactase-phlorizin hydrolase. [PNGH]
Lactase gene promoter fragments mediate differential spatial and temporal expression patterns in transgenic mice.
Inactivation of Gata4 (show GATA4 Proteins) had no effect on LPH gene expression, whereas inactivation of Hnf1alpha (show HNF1A Proteins) resulted in a 50% reduction in LPH gene expression during either cytodifferentiation or suckling.
Data found transport defects of the intestinal brush border hydrolases lactase-phlorizin hydrolase (LPH) in galectin-3 (show LGALS3 Proteins)-null mutant mice, showing that it directly interact with galectin-3 (show LGALS3 Proteins) and transit through non-raft-dependent apical transport platforms.
The frequency of -13910*T was significantly higher among the Mennonites when compared to the Euro-Brazilian cohort. Accordingly, Mennonites had a higher prevalence of the lactase persistence genotype
Populations from two medieval sites in Central Poland, Stary Brzesc Kujawski-4 (SBK (show SBK1 Proteins)-4) and Gruczno, represented high level of lactase persistence (LP) as followed by the LCT-13910*T allele's presence (0.86 and 0.82, respectively).
In conclusion, our data indicate that identification of a -13910C/C genotype is likely to predict the presence of lactase nonpersistence, in keeping with prior published studies.
Diversity of lactase persistence in African milk drinkers.
Evidence of selection around the LCT gene among Khoe-speaking groups, and the substantial frequency of the 14010C variant among the Nama is best explained by adaptation to digesting milk.
Report reliabile of the single nucleotide polymorphism of lactase persistence LPH(-13910) C/T from saliva (show RAG1AP1 Proteins) derived DNA.
Genotypes of neolithic human remains indicate that natural selection models satisfy the observed increase in allele frequency in lactase persistence.
Evolutionary history of the European lactase persistence trait and its global cultural implications.
The findings of this study suggest that at least the ApaI and BsmI polymorphisms of the VDR (show CYP27B1 Proteins) gene and T-13910C of the LCT gene are associated with the risk of postmenopausal osteoporosis in our sample of the Belarusian women.
Show new sequence data from the lactase gene for two Bedouin tribal populations, the Ajman and Mutran. Study the frequency of Lactase persistence associated alleles and discuss impact of nomadic-pastoralism on the associated genetic variation.
catalyzes the hydrolysis of pyridoxine-5'-beta-D-glucoside to release pyridoxine\; also catalyses the hydrolysis of lactose to D-glucose and D-galactose
, lactase phlorizin hydrolase
, pyridoxine-5'-beta-D-glucoside hydrolase
, lactase-phlorizin hydrolase
, lactase, gene 2
, lactase-phlorizin hydrolase-1