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LTF is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. Additionally we are shipping Lactoferrin Kits (71) and Lactoferrin Proteins (42) and many more products for this protein.
Showing 10 out of 459 products:
Human Monoclonal Lactoferrin Primary Antibody for FACS, IFA - ABIN1741598
Oehler, Majdic, Pickl, Stöckl, Riedl, Drach, Rappersberger, Geissler, Knapp: Neutrophil granulocyte-committed cells can be driven to acquire dendritic cell characteristics. in The Journal of experimental medicine 1998
Show all 14 references for ABIN1741598
Human Monoclonal Lactoferrin Primary Antibody for IF, IHC (p) - ABIN658977
Romero, Friel, Velez Edwards, Kusanovic, Hassan, Mazaki-Tovi, Vaisbuch, Kim, Erez, Chaiworapongsa, Pearce, Bartlett, Salisbury, Anant, Vovis, Lee, Gomez, Behnke, Oyarzun, Tromp, Williams, Menon: A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). in American journal of obstetrics and gynecology 2010
Show all 5 references for ABIN658977
Human Polyclonal Lactoferrin Primary Antibody for EIA, IHC (fro) - ABIN493053
Zimecki, Artym, Chodaczek, Kocieba, Kruzel: Protective effects of lactoferrin in Escherichia coli-induced bacteremia in mice: relationship to reduced serum TNF alpha level and increased turnover of neutrophils. in Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2004
Show all 4 references for ABIN493053
Dog (Canine) Polyclonal Lactoferrin Primary Antibody for EIA, IHC (fro) - ABIN302316
Hendrixson, Qiu, Shewry, Fink, Petty, Baker, Plaut, St Geme: Human milk lactoferrin is a serine protease that cleaves Haemophilus surface proteins at arginine-rich sites. in Molecular microbiology 2003
Show all 2 references for ABIN302316
Human Polyclonal Lactoferrin Primary Antibody for EIA, WB - ABIN453736
Willnow, Goldstein, Orth, Brown, Herz: Low density lipoprotein receptor-related protein and gp330 bind similar ligands, including plasminogen activator-inhibitor complexes and lactoferrin, an inhibitor of chylomicron remnant clearance. in The Journal of biological chemistry 1993
Human Polyclonal Lactoferrin Primary Antibody for IHC (p), WB - ABIN1882099
Pitteri, Kelly-Spratt, Gurley, Kennedy, Buson, Chin, Wang, Zhang, Wong, Chodosh, Nelson, Hanash, Kemp: Tumor microenvironment-derived proteins dominate the plasma proteome response during breast cancer induction and progression. in Cancer research 2011
Human Polyclonal Lactoferrin Primary Antibody for ELISA, WB - ABIN308453
de la Rosa, Yang, Tewary, Varadhachary, Oppenheim: Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses. in Journal of immunology (Baltimore, Md. : 1950) 2008
LTF C-lobe contributes to its anti-tumor activity.
M-860 induces the activation of huPMNs partially through TLR4 (show TLR4 Antibodies) ... M-860 is thus a powerful tool to analyze the expression and function of human mbLTF, which will further our understanding of the roles of LTF in health and disease.
LF triggered CREB1 (show CREB1 Antibodies) phosphorylation in IL-1beta (show IL1B Antibodies)-induced Human articular chondrocytes apoptosis through AKT1 (show AKT1 Antibodies) signaling.
the possible relationship between ocular symptomatology, tear volume and tear break-up time (TBUT) and lipocalin (show APOD Antibodies), lactoferrin and lysozyme (show LYZ Antibodies) concentrations in the tear film were explored in a group of symptomatic dry-eyed postmenopausal (PM) women.
Tear lysozyme (show LYZ Antibodies), lactoferrin and lipocalin (show APOD Antibodies) concentrations were determined via electrophoresis and the results for patients with or without eyelid tumors were compared.
Both the hLF (show EPAS1 Antibodies) and hLZ were expressed in the mammary gland of bi-transgenic pigs, as detected by western blotting.Interestingly, pig milk containing hLF (show EPAS1 Antibodies) and hLZ had synergistic antimicrobial activity
diagnostic contribution of calprotectin (show S100A8 Antibodies) and lactoferrin determinations in the cerebrospinal fluid when distinguishing between bacterial and aseptic meningitides
results suggest that LTF genetic polymorphisms Thr29Ala and Arg47Lys are not associated with susceptibility to HIV-1 MTCT, but our data are preliminary, obtained on low number of individual, also lacking of functional characterisation of the analysed SNPs
Results show that LTF gene expression is downregulated in colorectal cancer tumors and its knock out in mouse model of colitis-associated colorectal dysplasia suggests its protective role in colorectal mucosal immunity and inflammation.
Fecal lactoferrin levels were significantly higher in patients with pouchitis than those without pouchitis after restorative proctocolectomy for ulcerative colitis.
Bovine lactoferrin SNPs -270T>C and -156A>G showed close linkage disequilibrium (r(2)=0.76). The SNP -190G>A showed a significant association with SCS (show TWIST1 Antibodies), and individuals with genotype GG had higher SCS (show TWIST1 Antibodies) than genotypes AG and AA.
Lf upregulated several canonical signaling pathways associated with neurodevelopment and cognition and influenced ~10 genes involved in the brain-derived neurotrophin (show BDNF Antibodies) factor (BDNF (show BDNF Antibodies)) signaling pathway.
Results from this study indicated the probable role played by Lactoferrin promoter to serve as candidate gene for mastitis susceptibility among indigenous and crossbred milch cattle.
Supplementation with lactoferrin (1,600 mg/kg per day) effectively suppressed the increase in transepidermal water loss, reduction in skin hydration, aberrant epidermal hyperplasia, and cell apoptosis induced by UV irradiation.
Bovine Lf can capture and terminate the cycle of ROS (show ROS1 Antibodies) production by heme iron. Luminal iron binding properties of Lf might assist in regulating excess levels of stored iron and down-regulate ferritin (show FTL Antibodies) production and associated pro-inflammatory signaling.
The results showed potent stimulation of the proliferative response of PBMC by bovine lactoferrin, associated with the induction of proinflammatory cytokines only in the case of colostral bovine lactoferrin.
Lactoferrin (10 and 100 mug/mL) effectively inhibits apoptosis of primary rat osteoblasts by upregulating IGF-I (show IGF1 Antibodies) expression.
The the association between single nucleotide polymorphism (A/C) in position -28 located in the TATA box of LTF gene and the lactoferrin concentration in bovine milk secreted by healthy and infected udders.
This study showed that neutrophils from periparturient heifers show impairment of COX-2 (show PTGS2 Antibodies) mRNA expression and lactoferrin, suggesting that these mechanisms may contribute to immunosuppression in cows around calving.
results suggest a two-step mechanism, whereby LfcinB induces TIMP-1 (show TIMP1 Antibodies) through an IL-11 (show IL11 Antibodies)-dependent pathway involving transcription factor AP-1 (show JUN Antibodies) and STAT3 (show STAT3 Antibodies).
Data show that the expression of several genes encoding salivary antimicrobial proteins, such as secretory leukocyte peptidase inhibitor (SLPI (show SLPI Antibodies)), S100A8 (show S100A8 Antibodies), and lactotransferrin, was reduced due to myeloid differentiation dactor 88 (MyD88 (show MYD88 Antibodies)) deficiency.
Lactoferrin dampens high-fructose corn syrup-induced hepatic manifestations of the metabolic syndrome in a murine model.
We conclude that lactotransferrin represents a late stage differentiation marker of neutrophils, macrophages and distinct subtypes of dendritic cells.
The variations in lactoferrin expression levels during developmental stages may be related to its regulatory role in mouse mammary gland immunity.
the present work indicated that LF stimulated MC3T3-E1 preosteoblast differentiation mainly through LRP1 (show LRP1 Antibodies)-independent PKA and p38 (show CRK Antibodies) signaling pathways.
Studie indicate that in iCre knock-in line, the iCre is expressed from endogenous lactoferrin (Ltf) promoter.
administration of lactoferrin led to autopotentiated increased expression of the LTF gene. The decreased lactoferrin mRNA levels in association with obesity and diabetes were replicated in mice adipose tissue
The up-regulation of lactorferrin in the brains of the transgenic mouse model of Alzheimer's disease provides evidence of an important role for lactoferrin in alzheimer disease-affected brain tissues
Methoxychlor stimulates the mouse lactoferrin gene promoter through a GC-rich (show RELB Antibodies) element.
lactoferrin was found in the cytoplasm of principal cells in the corpus and cauda of the epididymis in peri (show PLIN1 Antibodies)- and post-pubertal, but not pre-pubertal stallions. Further, lactoferrin binds to sperm, suggesting a role for protection or regulation of sperm.
These data indicate that clinically normal skin of horses affected by CHS (show LYST Antibodies) is not characterized by modified maintenance levels of lactoferrin mRNA.
We propose that lactoferrin functions in the immune defense of the small intestinal mucosa by targeting the population of T cells in the lamina propria
Involvement of HSP27 (show HSPB1 Antibodies) and lactoferrin in porcine endometrium and neutrophils activity.
Growth performance of animal pups is enhanced by directly feeding the genetically engineered milk containing enriched pLF protein in transgenic mice.
This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, growth-inhibiting protein 12
, neutrophil lactoferrin
, N lobe
, minisatellite 10r detected by probe MMS10
, allergen Gal d III
, ovotransferrin BB type
, ovotransferrin BC type
, ovotransferrin CC type
, serum transferrin