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LAMC2 Antibodies

(Laminin, gamma 2 (LAMC2))
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins, composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively), have a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 2. The gamma 2 chain, formerly thought to be a truncated version of beta chain (B2t), is highly homologous to the gamma 1 chain\; however, it lacks domain VI, and domains V, IV and III are shorter. It is expressed in several fetal tissues but differently from gamma 1, and is specifically localized to epithelial cells in skin, lung and kidney. The gamma 2 chain together with alpha 3 and beta 3 chains constitute laminin 5 (earlier known as kalinin), which is an integral part of the anchoring filaments that connect epithelial cells to the underlying basement membrane. The epithelium-specific expression of the gamma 2 chain implied its role as an epithelium attachment molecule, and mutations in this gene have been associated with junctional epidermolysis bullosa, a skin disease characterized by blisters due to disruption of the epidermal-dermal junction. Two transcript variants resulting from alternative splicing of the 3' terminal exon, and encoding different isoforms of gamma 2 chain, have been described. The two variants are differentially expressed in embryonic tissues, however, the biological significance of the two forms is not known. Transcript variants utilizing alternative polyA_signal have also been noted in literature. [provided by RefSeq, Aug 2011].
LAMC2 antibody  (C-Term) LAMC2 antibody  (C-Term) LAMC2 antibody (C-Term) (ABIN3187887)

LAMC2 Reactivity: Human, Rat ELISA, IHC (p), WB Host: Rabbit Polyclonal unconjugated

LAMC2 antibody  (AA 417-588) LAMC2 antibody  (AA 417-588) LAMC2 antibody (AA 417-588) (ABIN7157898)

LAMC2 Reactivity: Human ELISA, IHC, WB Host: Rabbit Polyclonal unconjugated

LAMC2 antibody LAMC2 antibody LAMC2 antibody (ABIN7259891)

LAMC2 Reactivity: Human, Mouse, Rat IF Host: Rabbit Polyclonal unconjugated

LAMC2 Antibodies by Reactivity

Find LAMC2 Antibodies for a variety of species such as anti-Human LAMC2, anti-Mouse LAMC2, anti-Rat LAMC2. The species listed below are among those available. Click on a link to go to the corresponding products.

LAMC2 Antibodies by Application

Find LAMC2 Antibodies validated for a specific application such as WB, ELISA, IHC, ICC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

LAMC2 Antibodies by Host

Find LAMC2 Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

LAMC2 Antibodies by Binding Specificity

Find LAMC2 Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

LAMC2 Antibodies by Clonality

Find available monoclonal or polyclonal LAMC2 Antibodies. Click on a link to go to the corresponding products.

LAMC2 Antibodies by Clone

Find LAMC2 Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

LAMC2 Antibodies by Conjugate

Find LAMC2 Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular LAMC2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (3)
Cat. No. ABIN517440
Quantity 50 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC (p), WB
Validations
  • (3)
Cat. No. ABIN3031592
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IHC (p), WB
Validations
  • (2)
Cat. No. ABIN2856930
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application ICC, IHC, WB
Validations
  • (2)
Cat. No. ABIN1859607
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application ICC, IHC, WB
Validations
  • (2)
Cat. No. ABIN1980449
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC (p), WB
Validations
  • (2)
Cat. No. ABIN5650053
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB
Validations
  • (1)
Cat. No. ABIN7185092
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, ICC, IF, WB
Validations
  • (1)
Cat. No. ABIN6262902
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7157899
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7157900
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7157901
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, WB
Validations
Cat. No. ABIN7115765
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ICC, IHC, IP, WB
Validations
Cat. No. ABIN6996939
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ICC, IHC, IP, WB
Validations
Cat. No. ABIN6996941
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application ICC, IHC, IP, WB
Validations
Cat. No. ABIN6993376
Quantity 200 μL
Datasheet Datasheet

Latest Publications for our LAMC2 Antibodies

Parikh, Puram, Faquin, Richmon, Emerick, Deschler, Varvares, Tirosh, Bernstein, Lin: "Immunohistochemical quantification of partial-EMT in oral cavity squamous cell carcinoma primary tumors is associated with nodal metastasis." in: Oral oncology, Vol. 99, pp. 104458, (2019) (PubMed).

Amin, Janson, Sevéus, Miyazaki, Virtanen, Venge: "Uncoordinated production of Laminin-5 chains in airways epithelium of allergic asthmatics." in: Respiratory research, Vol. 6, pp. 110, (2005) (PubMed).

Aliases for LAMC2 Antibodies

laminin subunit gamma 2 (LAMC2) Antibodies
laminin, gamma 2 (Lamc2) Antibodies
laminin subunit gamma 2 (Lamc2) Antibodies
AA589349 Antibodies
B2T Antibodies
BM600 Antibodies
CSF Antibodies
EBR2 Antibodies
EBR2A Antibodies
LAMB2T Antibodies
LAMC2 Antibodies
LAMNB2 Antibodies
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