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anti-Lysophosphatidic Acid Receptor 1 (LPAR1) Antibodies

The integral membrane protein encoded by LPAR1 is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. Additionally we are shipping LPAR1 Kits (8) and LPAR1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
LPAR1 1902 Q92633
LPAR1 14745 P61793
LPAR1 116744 P61794
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Top anti-LPAR1 Antibodies at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC206065 overexpress plasmid (Re... HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane... 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$405.17
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemical staining of Brain (Neuron and Glia) using anti- ED... 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Immunofluorescence analysis of MCF7 cells, using LPAR1/EDG2 Antibody. ... Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE). 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB Anti-EDG2 antibody IHC staining of human kidney. Immunohistochemistry ... 1 each Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human pancreatic cancer labeled w... L1 Mouse liver lysates, L2 Mouse cerebrum lysates probed with Anti- ED... 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 8 to 10 Days
$451.00
Details

LPAR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Mouse (Murine) , ,

Rat (Rattus) , , , ,

Top referenced anti-LPAR1 Antibodies

  1. Human Polyclonal LPAR1 Primary Antibody for EIA, WB - ABIN358617 : Boucharaba, Serre, Guglielmi, Bordet, Clézardin, Peyruchaud: The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

More Antibodies against LPAR1 Interaction Partners

Human Lysophosphatidic Acid Receptor 1 (LPAR1) interaction partners

  1. LPA (show APOA Antibodies)-type agonist, via Carbonyl-oxygen/Lys39 interaction facilitates the formation of a hypothetical N-terminal cap tightly packed over the LPA1 heptahelical bundle.

  2. Data show high expression levels of LPAR2 (show LPAR2 Antibodies) and LPAR1 in endometrial cancer tissue with positive correlations with FIGO stage suggesting them as potential biomarkers for endometrial cancer progression.

  3. Data suggest LPA (lysophosphatidic acid; acting via LPAR1) and endothelin activate Cdc42, concurrent with biphasic decrease in Rac1 activity, differential effects on RhoA; LPA/endothelin stim. leads to remodeling of invadosomes in melanoma cells.

  4. we show that LPAR1 is a novel susceptibility gene for human essential hypertension and that stress, such as shortage of sleep, increases the susceptibility of patients with risk allele to essential hypertension.

  5. Study presents three crystal structures of LPA1 in complex with antagonist tool compounds selected and designed through structural and stability analyses.

  6. Results indicate that lysophosphatidic acid-lysophosphatidic acid receptor 1 (LPA (show APOA Antibodies)-LPA1) signaling contributes to the activation of rheumatoid arthritis fibroblast-like synoviocytes (FLSs).

  7. HB-EGF (show HBEGF Antibodies) is a biomarker for LPA1 receptor activation in human breast and prostate cancers.

  8. Lysophosphatidylethanolamine utilizes LPA(1) and CD97 (show CD97 Antibodies) in a breast cancer cell line.

  9. LPA1 and LPA2 (show LPAR2 Antibodies) are major LPA (show APOA Antibodies) receptor subtypes compared with low-expressed LPA3 (show LPAR3 Antibodies) in PANC-1 tumor cells.

  10. Lysophosphatidic acid (LPA) increased hepatocellular carcinoma cells cell invasion, which was LPA-receptor dependent.

Mouse (Murine) Lysophosphatidic Acid Receptor 1 (LPAR1) interaction partners

  1. Data show that lysophosphatidic acid (LPA) induces phosphorylation of trkA (show NTRK1 Antibodies) receptor (TrkA (show NTRK1 Antibodies)) through lysophosphatidic acid receptor 1 (LPA1) binding to TrkA (show NTRK1 Antibodies)

  2. LPA receptor has a role in bone loss in ovariectomized mice, but the favorable effect of its inhibition on bone remodeling is less general than hypothesized

  3. These findings suggest that tumor and stromal LPA receptors, in particular LPA1 and LPA5 (show LPAR5 Antibodies), play different roles in invasion and the seeding of metastasis

  4. LPA1 receptor is involved in emotional behaviors and in the anatomical integrity of the corticolimbic circuit, the deregulation of which may be a susceptibility factor for anxiety disorders.

  5. These results suggest that Ile325, Tyr85, and Leu87 within LPA1 are essential for LPA1 protein properly folding in the ER.

  6. These results suggest that LPA1 receptor-mediated amplification of spinal LPA production is required for the development of paclitaxel-induced neuropathic pain.

  7. these results demonstrate that LPA1 is essential for in vitro and in vivo osteoclast activities.

  8. Ultrastructural analyses of peripheral nerves in mouse null-mutants for LPA1 showed delayed schwann cell-to-axon segregation, polyaxonal myelination by single schwann cells, and thinner myelin sheaths.

  9. This study demonstrate a correlation between gene expression and cell birthdates. Lpar1 cells are preferentially generated on E11.5 and survive preferentially after the first postnatal week compared with other subplate neurons

  10. Lysophosphatidic acid receptor 1 is necessary for development of arthritis.

Cow (Bovine) Lysophosphatidic Acid Receptor 1 (LPAR1) interaction partners

  1. Lysophosphatidic acid stimulates PGE (show LIPF Antibodies)(2) production, cell viability, and intracellular calcium ion mobilization in cultured stromal endometrial cells via Ki16425-sensitive LPA1 receptors.

Zebrafish Lysophosphatidic Acid Receptor 1 (LPAR1) interaction partners

  1. the ATX-LPA-LPAR axis is a critical regulator of embryonic vascular development that is conserved in vertebrates

  2. LPA(1) is necessary for lymphatic vessel formation during embryonic development in zebrafish.

LPAR1 Antigen Profile

Protein Summary

The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene

Gene names and symbols associated with LPAR1

  • lysophosphatidic acid receptor 1 (LPAR1) antibody
  • lysophosphatidic acid receptor 1 (LOC100355169) antibody
  • lysophosphatidic acid receptor 1 (Lpar1) antibody
  • lysophosphatidic acid receptor 1 (lpar1) antibody
  • 5031439C20 antibody
  • AI326300 antibody
  • EDG-2 antibody
  • edg2 antibody
  • Gpcr26 antibody
  • GPR26 antibody
  • Kdt2 antibody
  • lpA1 antibody
  • Mrec1.3 antibody
  • rec.1.3 antibody
  • si:dz22b13.1 antibody
  • si:dz46m7.1 antibody
  • vzg-1 antibody
  • VZG1 antibody
  • zgc:92157 antibody

Protein level used designations for LPAR1

endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 , lysophosphatidic acid receptor 1 , lysophosphatidic acid receptor 1-like , LPA receptor 1 , LPA-1 , lysophosphatidic acid receptor Edg-2 , ventricular zone gene 1 , G-protein coupled receptor 26 , clone 4.9 , endothelial differentiation lysophosphatidic acid G-protein-coupled receptor 2 , rec1.3 , lpa1 , zlpa1 , endothelium differentiation gene 2

GENE ID SPECIES
427339 Gallus gallus
464655 Pan troglodytes
474800 Canis lupus familiaris
100355169 Oryctolagus cuniculus
100414340 Callithrix jacchus
100016607 Monodelphis domestica
100458931 Pongo abelii
100589911 Nomascus leucogenys
1902 Homo sapiens
14745 Mus musculus
116744 Rattus norvegicus
281136 Bos taurus
368461 Danio rerio
443346 Ovis aries
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