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Major Histocompatibility Complex, Class I, B Proteins (HLA-B)

HLA-B belongs to the HLA class I heavy chain paralogues. Additionally we are shipping HLA-B Antibodies (128) and HLA-B Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
HLA-B 3106 P01889
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Top HLA-B Proteins at

Showing 2 out of 77 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days

HLA-B Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,

More Proteins for Major Histocompatibility Complex, Class I, B (HLA-B) Interaction Partners

Human Major Histocompatibility Complex, Class I, B (HLA-B) interaction partners

  1. Genotyping and Computational Modeling in Prediction of Anti-epileptic Drugs that cause Stevens Johnson Syndrome and Toxic Epidermal Necrolysis for Carrier of HLA-B*15:02

  2. A number of HLA-B alleles and haplotypes showed susceptible (B*07) and protective (B*40, B*54, B*57, B*51) association(s) in T2DM patients from south India

  3. Combination of HLA-B*15:01 and DRB1*15:01 is associated with interstitial lung disease in Japanese patients with advanced pancreatic cancer receiving gemcitabine plus erlotinib.

  4. The results suggest that HLA-B*44:03 or other closely linked gene of the major histocompatibility complex is associated with susceptibility to the development of postherpetic neuralgia after herpes zoster, but not with the onset of herpes zoster.

  5. The effect of patient and/or donor HLA-B*51:01 on acute graft-versus-host disease was attributed not only to strong linkage disequilibrium of HLA-C* 14:02 and HLA-B*51:01, but also to the effect of HLA-B*51:01 itself.

  6. Data indicate that human platelet antigen (HPA) 1-16 and human leukocyte antigen (HLA)-A and -B are highly polymorphic among ethnic Hans from Shandong, China.

  7. HLA-B27 positivity and smoking are associated with a chondro-proliferative metabolic pattern in disease modifying antirheumatic agent-naive axial spondyloarthritis patients.

  8. Results showed that certain alleles of HLA, particularly HLA-B*56:02, were significantly associated with phenytoin-related Stevens-Johnson syndrome in the study population.

  9. These data indicate that HLA-B*57:01 carriage confers higher risk of ALT elevation in patients receiving pazopanib and provide novel insight implicating an immune-mediated mechanism for pazopanib-associated hepatotoxicity in some patients.

  10. These results demonstrate diverse spatiotemporal expression patterns for MHC class I molecules in the prenatal human CNS.

HLA-B Protein Profile

Protein Summary

HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.

Gene names and symbols associated with HLA-B

  • major histocompatibility complex, class I, B (BOLA-B)
  • major histocompatibility complex, class I, B (MAMU-B18)
  • major histocompatibility complex, class I, B (DKFZP469N1225)
  • major histocompatibility complex, class I, B (HLA-B)
  • AS protein
  • HLAB protein
  • SPDA1 protein

Protein level used designations for HLA-B

major histocompatibility complex, class I, B , HLA class I histocompatibility antigen, B alpha chain , MHC Class I HLA heavy chain , MHC HLA-B cell surface glycoprotein , MHC HLA-B transmembrane glycoprotein , MHC class I antigen GN00104 , MHC class I antigen HLA-B heavy chain , MHC class I antigen SHCHA , leukocyte antigen class I-B , lymphocyte antigen

282156 Bos taurus
100141394 Macaca mulatta
100173276 Pongo abelii
3106 Homo sapiens
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