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Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14) ELISA Kits

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as art. Additionally we are shipping MMP14 Antibodies (206) and MMP14 Proteins (23) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MMP14 4323 P50281
MMP14 17387 P53690
MMP14 81707 Q10739
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Top MMP14 ELISA Kits at antibodies-online.com

Showing 7 out of 24 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.62 ng/mL 1.56-100 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details
Mouse 35.58 pg/mL 93.75-6000 pg/mL 96 Tests Log in to see 9 to 11 Days
$757.89
Details
Rat 11.75 pg/ml 46.88-3000 pg/mL   96 Tests Log in to see 11 to 13 Days
$1,026.67
Details
Human
  96 Tests Log in to see 2 to 3 Days
$380.00
Details
Please inquire
1 kit Log in to see 2 to 3 Days
$502.70
Details
Pig
0.78-50 ng/mL   96 Tests Log in to see 11 to 13 Days
$1,029.60
Details
Cow
  96 Tests Log in to see 11 to 13 Days
$1,029.60
Details

Top referenced MMP14 ELISA Kits

  1. Human MMP14 ELISA Kit for Sandwich ELISA - ABIN415141 : Kaimal, Aljumaily, Tressel, Pradhan, Covic, Kuliopulos, Zarwan, Kim, Sharifi, Agarwal: Selective blockade of matrix metalloprotease-14 with a monoclonal antibody abrogates invasion, angiogenesis, and tumor growth in ovarian cancer. in Cancer research 2013 (PubMed)
    Show all 3 references for ABIN415141

  2. ABIN1882505 : Sugimoto, Ishibashi, Sawamura, Inoue, Kamioka, Uekita, Ohkawara, Sakamoto, Sakamoto, Okamoto, Takuwa, Kakino, Fujita, Tanaka, Teramoto, Maruyama, Takeishi: LOX-1-MT1-MMP axis is crucial for RhoA and Rac1 activation induced by oxidized low-density lipoprotein in endothelial cells. in Cardiovascular research 2009 (PubMed)
    Show all 2 references for ABIN1882505

More ELISA Kits for MMP14 Interaction Partners

Human Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14) interaction partners

  1. Silencing KIF1B (show KIF1B ELISA Kits) inhibited expression of membranal MT1-MMP in glioma cells; however, the amount of MT1-MMP in the whole cell lysate was not affected.

  2. Independent prognostic value of MMP-14 expression in ovarian cancer is limited to a role in PFS for stromal MMP-14.

  3. Data indicate that miR (show MLXIP ELISA Kits)-337-3p directly binds the MMP-14 promoter to repress its transcription, thus suppressing the progression of NB.

  4. Results identify the tumor suppressor SPRY4 (show SPRY4 ELISA Kits) as a novel molecular effector of MT1-MMP affecting melanoma cell motility.

  5. Pressure and Temperature Effects on the Activity and Structure of the Catalytic Domain of Human MT1-MMP

  6. MiR (show MLXIP ELISA Kits)-22 downregulation promotes GC invasion and metastasis by upregulating MMP14 and Snail (show SNAI1 ELISA Kits), and then inducing ECM (show MMRN1 ELISA Kits) remodeling and EMT (show ITK ELISA Kits).

  7. MT1-MMP islets thus act as cellular memory devices.

  8. Overexpression of MT1-MMP in HT-1080 (show CDC123 ELISA Kits) cells does not significantly alter the invasive ability of these cells.

  9. positive MT1-MMP immunostaining could be found in synoviocytes, vascular endothelial cells, infiltrating macrophages and monocytes in rheumatoid arthritis synovium tissues

  10. TIMP2 (show TIMP2 ELISA Kits)-based and enediyne-integrated fusion protein targets MMP-14 in colorectal and esophageal neoplasms to suppress growth.

Mouse (Murine) Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14) interaction partners

  1. MT1-MMP directly cleaves LYVE-1 (show LYVE1 ELISA Kits) on lymphatic endothelial cells to inhibit LYVE-1 (show LYVE1 ELISA Kits)-mediated lymphangiogenic responses and restrains the production of VEGF-C (show VEGFC ELISA Kits).

  2. The authors propose a model for cell-regulated collagen fibril assembly during tendon development in which MMP14 cleaves a molecular bridge tethering collagen fibrils to the plasma membrane of fibripositors.

  3. We demonstrate that MMP-14-mediated signaling in fetal hepatic progenitor cells promotes biliary luminal formation around the portal vein and negatively controls the maturation of hepatocytes.

  4. Results show a reciprocal association between levels of heparanase (show HPSE ELISA Kits) and MMP14, a membrane-bound MMP, shedding light on how branching occurs within developing mammary glands.

  5. MT1-MMP proteolytic activity is required for maintaining cell integrity, loss of MT1-MMP causes cell senescence and nuclear defects.

  6. of the transcripts of tissue inhibitors of matrix metalloproteinases (TIMPs) showed that expression of both TIMP1 (show TIMP1 ELISA Kits) and TIMP2 (show TIMP2 ELISA Kits) correlates negatively with the invasive potential of cells.

  7. Angiotensin II suppresses RECK (show RECK ELISA Kits), but induces matrix metalloproteinases both in vivo and in vitro.

  8. Active MT1-MMP promotes Notch1 (show NOTCH1 ELISA Kits) cleavage independently of ADAM10 (show ADAM10 ELISA Kits) or -17.

  9. LV mass was similar among WT, MT1-MMP overexpression, and MT1-MMP reduced expression after PO, significant differences in LV function.

  10. In the kidneys of Sirt1 (show SIRT1 ELISA Kits)(endo-/-) mice, impaired angiogenesis, reduced matrilytic activity, and retention of the profibrotic cleavage substrates tissue transglutaminase (show TGM2 ELISA Kits) and endoglin (show ENG ELISA Kits) accompanied MMP-14 suppression.

Cow (Bovine) Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14) interaction partners

  1. Data indicate the involvement of PKC-alpha (show PKCa ELISA Kits) in proMMP-2 activation and inhibition of TIMP-2 (show TIMP2 ELISA Kits) expression by NF-kappaB (show NFKB1 ELISA Kits)-MT1-MMP-dependent and -independent pathway.

  2. Data suggest that EMMPRIN derived from endometrial epithelial cells regulates expression of matrix metalloproteinases (MMP-2 (show MMP2 ELISA Kits); MMP-14) in endometrial stromal cells; expression of stromal MMPs is significantly higher in coculture with epithelial cells.

  3. MMP-14, MMP-2 (show MMP2 ELISA Kits) and TIMP-2 (show TIMP2 ELISA Kits) are co-localized in the fetal compartment and therefore could influence the timely release of fetal membranes in cattle.

  4. Results describe distinct changes in expression of MMP2 (show MMP2 ELISA Kits), MMP14, and the metallopeptidase (show ECEL1 ELISA Kits) inhibitor TIMP2 (show TIMP2 ELISA Kits) between different phases of the estrous cycle indicating an endocrine regulation.

  5. EMMPRIN from the luminal epithelium may regulate the expression of stromal MMP-2 (show MMP2 ELISA Kits) and MMP-14 suggesting a role in adhesion and fusion of embryo to luminal epithelium.

  6. MT1-MMP seems to act by inducing tissue remodeling in cartilage

  7. sphingosine 1-phosphate is the predominant serum factor essential for MT1-MMP-dependent migration and morphogenic differentiation of vascular endothelial cells

Rabbit Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14) interaction partners

  1. MT1-MMP plays a crucial role in RAGE (show AGER ELISA Kits)-activated NADPH oxidase (show NOX1 ELISA Kits)-dependent signaling pathways.

  2. MMP-1 (show MMP1 ELISA Kits) was involved in osteoarthritis development in rabbit ACLT model and the amount of its expression was related with the degree of cartilage degradation.

Pig (Porcine) Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14) interaction partners

  1. Modulation of MT1-MMP activity and microRNA-133a exportation into the myocardial interstitium occurred in the setting of acute myocardial ischemia-reperfusion.

  2. A heterogeneous response in MT1-MMP activity likely contributes to regional dysfunction with ischemia-reperfusion. Subsequent I/R activates a proteolytic cascade within the MI region, contributing to continued adverse remodeling.

  3. PI3K-dependent regulation of MT1-MMP protein synthesis and subsequent activation of latent MMP-2 (show MMP2 ELISA Kits) as critical events in neointimal hyperplasia after vascular injury.

  4. Induction of endogenous MMP-14 gene and coexpression of SAF-1 & MMP-14 in the macrophages present in the atherosclerotic plaque implicate SAF-1 as a key regulator of MMP-14 gene induction in macrophage cells.

  5. In an isolated left ventricular myocyte ischemia/reperfusion model, hypoxia induced a >70% increase in MT1-MMP abundance in myocytes. Confocal microscopy revealed MT1-MMP internalization during this time & reemergence to the membrane with reperfusion.

MMP14 Antigen Profile

Antigen Summary

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily\; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.

Gene names and symbols associated with MMP14

  • matrix metallopeptidase 14 (membrane-inserted) (mmp14) antibody
  • matrix metallopeptidase 14 (membrane-inserted) (MMP14) antibody
  • matrix metallopeptidase 14 (membrane-inserted) (Mmp14) antibody
  • AI325305 antibody
  • MMP-14 antibody
  • MMP-X1 antibody
  • MMP1 antibody
  • MT-MMP antibody
  • MT-MMP-1 antibody
  • MT-MMP 1 antibody
  • Mt1-mmp antibody
  • MT1MMP antibody
  • MTMMP1 antibody
  • sabe antibody

Protein level used designations for MMP14

matric metalloproteinase 14 , matrix metalloproteinase-14 , membrane type 1 metalloprotease , membrane-type-1 matrix metalloproteinase , MMP-14 , MMP-X1 , MT-MMP 1 , MT1MMP , MTMMP1 , Membrane type 1-MMP , matrix metalloproteinase 14 (membrane-inserted) , membrane-type matrix metalloproteinase 1 , type 1 matrix metalloprotease 14 , matrix metalloproteinase 14 membrane-inserted , matrix metalloproteinase 14, membrane-inserted , membrane type 1-matrix metalloproteinase , MT1-MMP , matrix metalloproteinase 14 preproprotein , matrix metallopeptidase 1 (interstitial collagenase) , matrix metalloproteinase 14 , membrane type 1 metalloproteinase , membrane-type 1 matrix metalloproteinase , membrane type-1 metalloproteinase

GENE ID SPECIES
594950 Xenopus (Silurana) tropicalis
4323 Homo sapiens
17387 Mus musculus
81707 Rattus norvegicus
281915 Bos taurus
100009598 Oryctolagus cuniculus
397471 Sus scrofa
443116 Ovis aries
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