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Mediterranean Fever Proteins (MEFV)

MEFV encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Additionally we are shipping Mediterranean Fever Antibodies (64) and Mediterranean Fever Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MEFV 4210 O15553
MEFV 54483 Q9JJ26
MEFV 58923 Q9JJ25
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Top Mediterranean Fever Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$4,194.67
Details

MEFV Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Mediterranean Fever (MEFV) Interaction Partners

Human Mediterranean Fever (MEFV) interaction partners

  1. Healthy individuals may bear E148Q and K695R MEFV gene mutations, as well as R202Q polymorphism in homozygous state. The determined gene alterations contribute to a subtle oxidative stress and may be associated with more frequent episodes of fever and unspecific inflammatory manifestations.

  2. the presence of homozygous M694V gene mutation seems to increase the risk for periodontitis in familial Mediterranean fever patients.

  3. Describe the MEFV mutational spectrum and distribution in a healthy Turkish population, and report a carrier rate that is much higher than expected.

  4. This study shows that p.M694I homozygosity in MEFV is a potential genetic risk factor for the development of renal AA-amyloidosis in Algerian Familial Mediterranean fever patients.

  5. Fever and MEFV gene M694V homozygosity were less frequently detected in Familial Mediterranean fever.

  6. Correlate MEFV genotype and the SAA1 (show SAA1 Proteins) polymorphisms with the clinical manifestations of familial Mediterranean fever and the occurrence of amyloidosis in a large cohort of Armenian patients.

  7. a guard-like mechanism of pyrin regulation, originally identified for Nod-like receptors in plant innate immunity, also exists in humans.

  8. Most patients presenting with PFAPA syndrome have heterozygous MEFV gene mutations.

  9. When compared with the control group, a lower prevalence of the MEFV gene mutation carrier was found in sarcoidosis patients but this was not statistically significant.

  10. This is the first report of non-transmitted, acquired familial Mediterranean fever, associated with a Janus Kinase 2 (show JAK2 Proteins) driven clonal expansion of a somatic Mediterranean fever gene exon 10 mutation.

Mouse (Murine) Mediterranean Fever (MEFV) interaction partners

  1. These results are consistent with a model in which pyrin acts to limit the release of IL-1beta (show IL1B Proteins) generated by activation and assembly of inflammasomes in response to subclinical immune challenges.

  2. pyrin has a critical role in the innate immune response, possibly by acting on ASC (show STS Proteins), a known caspase-1 (show CASP1 Proteins) activator

Mediterranean Fever (MEFV) Protein Profile

Protein Summary

This gene encodes a protein, also known as pyrin or marenostrin, that is an important modulator of innate immunity. Mutations in this gene are associated with Mediterranean fever, a hereditary periodic fever syndrome.

Gene names and symbols associated with Mediterranean Fever Proteins (MEFV)

  • Mediterranean fever (MEFV)
  • Mediterranean fever (Mefv)
  • pyrin-like (LOC529195)
  • FMF protein
  • MEF protein
  • MEFV protein
  • pyrin protein
  • rfp domain protein
  • TRIM20 protein

Protein level used designations for Mediterranean Fever Proteins (MEFV)

Mediterranean fever protein , Mediterranean fever , pyrin-like , marenostrin , pyrin , familial mediterranean fever

GENE ID SPECIES
467886 Pan troglodytes
701927 Macaca mulatta
100387055 Callithrix jacchus
100477997 Ailuropoda melanoleuca
100592337 Nomascus leucogenys
4210 Homo sapiens
490041 Canis lupus familiaris
54483 Mus musculus
58923 Rattus norvegicus
529195 Bos taurus
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