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Musashi Homolog 1 (Drosophila) Proteins (MSI1)

MSI1 encodes a protein containing two conserved tandem RNA recognition motifs. Additionally we are shipping MSI1 Antibodies (115) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MSI1 4440 O43347
MSI1 17690 Q61474
MSI1 259272 Q8K3P4
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Top MSI1 Proteins at

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

MSI1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Musashi Homolog 1 (Drosophila) (MSI1) Interaction Partners

Fruit Fly (Drosophila melanogaster) Musashi Homolog 1 (Drosophila) (MSI1) interaction partners

  1. show specific evidence for a cell-autonomous requirement for Msi family proteins in regulating stem cell differentiation, leading to the identification of an RNA-binding protein required for spermatogonial stem cell maintenance

Human Musashi Homolog 1 (Drosophila) (MSI1) interaction partners

  1. miR (show MLXIP Proteins)-761 and MSI1 are inversely expressed in ovarian cancer tissues. In conclusion, we demonstrated that miR (show MLXIP Proteins)-761 repressed ovarian cancer proliferation and invasion by targeting MSI1

  2. Concomitant loss of function of both MSI1 is sufficient to abrogate the growth of human colorectal cancer cells, and Msi gene deletion inhibits tumorigenesis in several mouse models of intestinal cancer.

  3. Msi1 overexpression is associated with Esophageal Squamous Cell Carcinoma.

  4. studies highlight Msi reporters as a unique tool to identify therapy resistance, and define Msi signalling as a central regulator of pancreatic cancer

  5. Musashi-1 and ALDH1 (show ALDH1A1 Proteins) expression are closely related to metastasis of ovarian adenocarcinoma.

  6. Suggest high level of Musashi-1 protein expression is associated with poor survival in endometrioid adenocarcinoma patients.

  7. Our results demonstrate that miR (show MLXIP Proteins)-137 acts as a tumor-suppressive miRNA in colorectal cancers and negatively regulates oncogenic Musashi-1

  8. This review highlights both the essential contribution of RBPs to posttranscriptional regulation and the importance of the Musashi family as master regulators of male gamete development--{REVIEW}

  9. data suggest that in response to environmental cues that oppose cell cycle progression, regulation of Musashi function is required to promote target mRNA translation and cell fate transition

  10. oncogenic role in hepatocellular carcinoma may be through modulation of cell growth and cell cycle by activating Wnt (show WNT2 Proteins) pathway via direct downregulation of APC (show APC Proteins) and DKK1 (show DKK1 Proteins)

Mouse (Murine) Musashi Homolog 1 (Drosophila) (MSI1) interaction partners

  1. Given that deregulated fatty acid metabolism plays a key role in kidney fibrosis, these results demonstrate a novel connection between fatty acid and Msi1, an RNA-binding protein, in kidney fibrosis

  2. A Mouse Model of Targeted Musashi1 Expression in Whole Intestinal Epithelium Suggests Regulatory Roles in Cell Cycle and Stemness.

  3. studies highlight Msi (show EBP Proteins) reporters as a unique tool to identify therapy resistance, and define Msi (show EBP Proteins) signalling as a central regulator of pancreatic cancer

  4. the RNA-binding protein Musashi 1 competes with miR130a and -206 for interaction with tachykinin mRNA

  5. MSI1 and MSI2 (show MSI2 Proteins) display distinct expression profiles during mammalian folliculogenesis and that MSI2 (show MSI2 Proteins) is required for pre-antral follicle development

  6. Osteoarticular expression of Msi1 protein is increased in joints with CIA (show NCOA5 Proteins)-induced lesion and absent in nonlesioned joints, suggesting that this protein is expressed when the lesion is produced in order to favor tissue repair.

  7. Msi1 is critical for constructing functional blood-testis barrier &maintaining spermatogenesis. Msi1 regulates Sertoli cell fate following heat-induced injury, likely through induction of stress granule formation & activation of p-ERK1/2 signaling

  8. Through expression studies and utilizing a transgenic Msi1 testis-specific (show AIF1 Proteins) overexpression model, we have identified 2 unique RNA-binding targets of MSI1 in spermatogonia, Msi2 (show MSI2 Proteins) and Erh (show ERH Proteins), and have demonstrated a role for MSI1 in translational regulation.

  9. Msi (show EBP Proteins) proteins contribute to an epithelial gene expression program in neural and mammary cell types.

  10. MSI1 is specifically inhibited by 18-22 carbon omega-9 monounsaturated fatty acids; MSI1 regulates stearoyl-CoA desaturase (show SCD Proteins)

Xenopus laevis Musashi Homolog 1 (Drosophila) (MSI1) interaction partners

  1. specific association of Musashi with the noncanonical poly(A) polymerase (show PAPOLA Proteins) germ line development defective-2 (GLD2 (show PAPD4 Proteins))

  2. Xenopus Musashi proteins regulate translation of the Musashi1 mRNA during oocyte maturation.

  3. Ringo/cyclin-dependent kinase (show CDK1 Proteins) and mitogen-activated protein kinase (show MAPK1 Proteins) signaling pathways regulate the activity of the cell fate determinant Musashi to promote cell cycle re-entry in Xenopus oocytes.

  4. These findings indicate that Musashi function is necessary to establish the temporal order of maternal mRNA translation during Xenopus meiotic cell cycle progression.

  5. Msi-1 expression is upregulated in the adult progenitor cells and plays important roles in their maintenance and/or active proliferation during amphibian gastrointestinal remodeling.

  6. Visual deprivation for 2 days increased proliferation of musashi1-immunoreactive radial glial progenitors

MSI1 Protein Profile

Protein Summary

This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13.

Gene names and symbols associated with MSI1

  • musashi (msi)
  • musashi RNA-binding protein 1 (msi1)
  • GD21224 gene product from transcript GD21224-RA (Dsim\\msi)
  • musashi 1 (LOC100352797)
  • musashi homolog 1 (Drosophila) (MSI1)
  • musashi RNA-binding protein 1 (MSI1)
  • musashi RNA-binding protein 1 (Msi1)
  • anon-EST:Liang-2.35 protein
  • CG5099 protein
  • clone 2.35 protein
  • Dmel\\CG5099 protein
  • DMSIDNA protein
  • Dsim\\GD21224 protein
  • dsim_GLEANR_4982 protein
  • GD21224 protein
  • m-Msi-1 protein
  • msi protein
  • msi1h protein
  • Musahi1 protein
  • musashi protein
  • Musashi-1 protein
  • Musashi1 protein
  • nrp-1B protein
  • SIDNA protein
  • XNrp-1 protein

Protein level used designations for MSI1

CG5099-PA , CG5099-PB , CG5099-PC , CG5099-PD , CG5099-PE , CG5099-PF , CG5099-PH , msi-PA , msi-PB , msi-PC , msi-PD , msi-PE , msi-PF , msi-PH , mushashi , musashi homolog 1 , Musashi 1 , Dsim\\GD21224-PA , Dsim\\msi-PA , GD21224-PA , msi , musashi 1 , RNA-binding protein Musashi homolog 1 , RNA-binding protein Musashi-1 , musashi-1 , musashi1 , Musashi homolog 1(Drosophila) , nrp-1B

43087 Drosophila melanogaster
496961 Xenopus (Silurana) tropicalis
6729631 Drosophila simulans
100352797 Oryctolagus cuniculus
527436 Bos taurus
4440 Homo sapiens
17690 Mus musculus
259272 Rattus norvegicus
399271 Xenopus laevis
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