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Myocyte Enhancer Factor 2D Proteins (MEF2D)

MEF2D is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Additionally we are shipping MEF2D Antibodies (123) and MEF2D Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
MEF2D 4209 Q14814
MEF2D 17261  
MEF2D 81518 O89038
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Top MEF2D Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,439.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

MEF2D Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Myocyte Enhancer Factor 2D (MEF2D) Interaction Partners

Human Myocyte Enhancer Factor 2D (MEF2D) interaction partners

  1. miR (show MLXIP Proteins)-1244 and MEF2D form an autoregulatory loop contributing to the progression of lung carcinoma.

  2. MEF2D was also found to increase the transcription of Pokemon (show ZBTB7A Proteins) by binding myocyte enhancer factor 2 (MEF2 (show MEF2A Proteins)) sites within its promoter region, that can promote Hepatocellular carcinoma invasion

  3. Cell cycle progression was also inhibited by MEF2D suppression.

  4. OA induced cell cycle arrest in lung cancer cells through miR (show MLXIP Proteins)-122/Cyclin G1 (show CCNG1 Proteins)/MEF2D pathway. This finding may contribute to the understanding of the molecular mechanism of OA's anti-tumor activity

  5. MEF2C and MEF2D interact with the E3 ligase F-box protein SKP2, which mediates their subsequent degradation through the ubiquitin-proteasome system.

  6. MEF2D suppression was shown to decrease the proliferation of osteosarcoma cells.

  7. Oxidation of survival factor MEF2D inhibits its function, underlies oxidative stress-induced (show SQSTM1 Proteins) neurotoxicity, and may be a part of the Parkinson disease pathogenic process.

  8. The oncogenic properties of rhabdomyosarcoma cells can be partially attributed to the loss of MEF2D expression.

  9. MEF2D-silencing abolished hepatocellular carcinoma tumorigenicity.

  10. The expression of MEF2D was higher in the higher clinical stage of nasopharyngeal carcinoma, but there was no correlation with survival rate.

Mouse (Murine) Myocyte Enhancer Factor 2D (MEF2D) interaction partners

  1. These findings uncover a novel role for Mef2c (show MEF2C Proteins)/d in coordinating the transcriptional network that promotes early B-cell development.

  2. This study identifies MEF2D as a critical regulator of IL-10 (show IL10 Proteins) gene expression that negatively controls microglia inflammation response and prevents inflammation-mediated cytotoxicity.

  3. Mef2d is essential for the maturation and integrity of retinal photoreceptor and bipolar cells

  4. miR (show MLXIP Proteins)-103 worked through activating AKT (show AKT1 Proteins)/mTOR (show FRAP1 Proteins) signal pathway and impairing target gene MEF2D.

  5. These findings demonstrate that broadly expressed TFs acquire specific functions through competitive recruitment to enhancers by tissue-specific Mef2d and through selective activation of these enhancers to regulate tissue-specific genes.

  6. Whereas MEF2A (show MEF2A Proteins) is absolutely required for proper myoblast differentiation, MEF2B (show MEF2B Proteins), -C, and -D were found to be dispensable for this process.

  7. A role for endogenous MEF2 (show MEF2C Proteins) factors exclusively in hormone/Fsk/cAMP-induced Nr4a1 (show NR4A1 Proteins) gene expression in mouse MA-10 Leydig cells.

  8. Oxidation of survival factor MEF2D inhibits its function, underlies oxidative stress-induced (show SQSTM1 Proteins) neurotoxicity, and may be a part of the Parkinson disease pathogenic process.

  9. Results demonstrate that coordinated alternative splicing by a single RNA binding protein modulates transcription (Mef2d) and cell signaling (Rock2 (show ROCK2 Proteins)) programs to drive tissue-specific functions (cell fusion) to promote a developmental transition.

  10. We found that Parkinson's disease -associated neurotoxins destabilize MEF2D mRNA and reduce its level in vitro and in vivo.

Cow (Bovine) Myocyte Enhancer Factor 2D (MEF2D) interaction partners

  1. Expression analysis showed that the MEF2D polymorphisms were highly correlated with MEF2D mRNA and protein levels in the longissimus dorsi muscle of Polish Holstein-Friesian bulls carrying the three different combined genotypes.

MEF2D Protein Profile

Protein Summary

This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with MEF2D

  • myocyte enhancer factor 2D (mef2d)
  • myocyte enhancer factor 2D (MEF2D)
  • MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) (MEF2D)
  • myocyte enhancer factor 2D (Mef2d)
  • C80750 protein
  • MGC145245 protein
  • sl-1 protein
  • sl1 protein
  • XMEF2D protein

Protein level used designations for MEF2D

myocyte enhancer factor 2D , MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) , myocyte-specific enhancer factor 2D-like , MADS box transcription enhancer factor 2, polypeptide D , myocyte-specific enhancer factor 2D

GENE ID SPECIES
780389 Xenopus (Silurana) tropicalis
100023326 Monodelphis domestica
100406906 Callithrix jacchus
100459204 Pongo abelii
769067 Gallus gallus
4209 Homo sapiens
17261 Mus musculus
81518 Rattus norvegicus
490413 Canis lupus familiaris
100156714 Sus scrofa
100336730 Bos taurus
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