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Myotubularin Related Protein 14 (MTMR14) ELISA Kits

MTMR14 encodes a myotubularin-related protein. Additionally we are shipping Myotubularin Related Protein 14 Antibodies (65) and Myotubularin Related Protein 14 Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
MTMR14 64419 Q8NCE2
MTMR14 97287 Q8VEL2
Anti-Rat MTMR14 MTMR14 312634  
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More ELISA Kits for Myotubularin Related Protein 14 Interaction Partners

Zebrafish Myotubularin Related Protein 14 (MTMR14) interaction partners

  1. Morpholino-mediated knockdown of MTMR14 results in morphologic abnormalities, a developmental motor phenotype characterized by diminished spontaneous contractions and abnormal escape response, and impaired excitation-contraction coupling.

Human Myotubularin Related Protein 14 (MTMR14) interaction partners

  1. This study provides the first in vivo evidence for a role of myotubularins, and in particular MTMR14, in the regulation of autophagy.

  2. The authors uncovered a key negative regulatory role in autophagy of a phosphatidylinositol 3-phosphate (PI3P) phosphatase Jumpy (MTMR14).

  3. C3orf29 encodes hJUMPY, a phosphoinositide 3-phosphate phosphatase that acts on PtdIns3P and PtdIns(3,5)P2. A missense mutation disrupts the catalytic activity in a patient with centronuclear myopathy.

Mouse (Murine) Myotubularin Related Protein 14 (MTMR14) interaction partners

  1. Data (including data from studies in knockout mice) suggest that Mtmr14 plays role in lipid metabolism and inflammation in liver, skeletal muscle, and adipose tissue in obesity induced by high-fat diet (HFD); here, Mtmr14 deficiency in knockout mice accelerates HFD-induced inflammation and metabolic dysfunction (obesity, hyperglycemia, and hyperlipidemia).

  2. propose that defect of MTMR14 promotes autophagy and cell proliferation in MEFs

  3. In young Mtmr14 KO mice (12 weeks). The T-tubule dysmorphology (swollen and elongated) could explain, in part, the defects in Ca2thorn excitationcontraction machinery observed in previous studies.

  4. MTMR14 may play an important role in muscle calcium homeostasis.

  5. Data report that mice deficient in the newly identified phosphatidylinositol phosphate phosphatase MIP (show MIP ELISA Kits)/MTMR14 (muscle-specific (show EIF3K ELISA Kits) inositol phosphatase) show muscle weakness and fatigue.

Myotubularin Related Protein 14 (MTMR14) Antigen Profile

Antigen Summary

This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.

Gene names and symbols associated with MTMR14

  • myotubularin related protein 14 (mtmr14) antibody
  • myotubularin related protein 14 (MTMR14) antibody
  • myotubularin related protein 14 (Mtmr14) antibody
  • 1110061O04Rik antibody
  • AW553738 antibody
  • C3orf29 antibody
  • C76151 antibody
  • fc14d11 antibody
  • jumpy antibody
  • MGC131146 antibody
  • RGD1304842 antibody
  • wu:fc14d11 antibody

Protein level used designations for MTMR14

myotubularin related protein 14 , myotubularin-related protein 14-like , HCV NS5A-transactivated protein 4 splice variant A-binding protein 1 , NS5ATP4ABP1 , egg-derived tyrosine phosphatase homolog , jumpy , myotubularin-related protein 14 , mJumpy

323929 Danio rerio
703936 Macaca mulatta
734951 Xenopus laevis
100014047 Monodelphis domestica
100036693 Xenopus (Silurana) tropicalis
100224025 Taeniopygia guttata
100397575 Callithrix jacchus
100542441 Meleagris gallopavo
100554543 Anolis carolinensis
64419 Homo sapiens
97287 Mus musculus
312634 Rattus norvegicus
484668 Canis lupus familiaris
416048 Gallus gallus
100157480 Sus scrofa
514596 Bos taurus
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