anti-NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1) Antibodies

The protein encoded by NDUFS1 belongs to the complex I 75 kDa subunit family. Additionally we are shipping NDUFS1 Proteins (4) and NDUFS1 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
NDUFS1 227197 Q91VD9
NDUFS1 301458 Q66HF1
NDUFS1 4719 P28331
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Top anti-NDUFS1 Antibodies at

Showing 10 out of 76 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB Lanes:  Lane1: 30 ug Human liver Lane2: 30 ug Rat liver Lane3: 30 ug Mouse (wild-type) liver Lane4: 30 ug Mouse [AMPK alpha 1/2(-/-)] liver Lane5: 30 ug Human muscle Lane6: 30 ug Rat muscle Lane7: 30 ug Mouse muscle Primary Antibody Dilution:  1:1000 Secondary Antibody:   Secondary Antibody Dilution:  1:10000 Gene Name:  NDUFS1 Submitted by:  Dr. Bruno Guigas, PhD, Dept. of Molecular Cell Biology, Leiden University Medical Center nuclear lysates 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated WB Host: Rabbit  Target Name: Ndufs1  Sample Tissue: Rat Thymus lysates  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 2 to 3 Days
Cow Goat Un-conjugated EIA, WB   0.1 mg Log in to see 12 to 15 Days
Human Goat Un-conjugated ELISA, WB Western Blot: Ndufs1 Antibody [NBP1-52060] - (0.3ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IHC (p), WB WB Image NDUFS1 antibody detects NDUFS1 protein by Western blot analysis. A. 50 µg rat brain lysate/extract 7.5 % SDS-PAGE NDUFS1 antibody , dilution: 1:500 WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 7.5% SDS PAGE antibody diluted at 1:10000 100 μL Log in to see 1 to 2 Days
Bat Goat Un-conjugated IHC (p), ELISA, WB Anti-NDUFS1 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1103219 concentration 5 ug/ml. 50 μg Log in to see 7 to 9 Days
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
Human Mouse Un-conjugated WB Western Blot analysis of NDUFS1 expression in transfected 293T cell line by NDUFS1 MaxPab polyclonal antibody.Lane 1: NDUFS1 transfected lysate(79.97 KDa).Lane 2: Non-transfected lysate. NDUFS1 MaxPab polyclonal antibody. Western Blot analysis of NDUFS1 expression in human spleen. 50 μg Log in to see 11 to 12 Days
Cow Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of NDUFS1 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of NDUFS1 expression in HeLa (A), SP2/0 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days

NDUFS1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-NDUFS1 Antibodies

  1. Human Polyclonal NDUFS1 Primary Antibody for WB - ABIN518248 : Sheftel, Stehling, Pierik, Netz, Kerscher, Elsässer, Wittig, Balk, Brandt, Lill: Human ind1, an iron-sulfur cluster assembly factor for respiratory complex I. in Molecular and cellular biology 2009 (PubMed)

  2. Human Polyclonal NDUFS1 Primary Antibody for IHC, ELISA - ABIN1451382 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005 (PubMed)

  3. Human Polyclonal NDUFS1 Primary Antibody for ELISA, WB - ABIN4338410 : Saito, Kawamoto, Kamatani: Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. in Journal of human genetics 2009 (PubMed)

More Antibodies against NDUFS1 Interaction Partners

Mouse (Murine) NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1) interaction partners

  1. lysosomal membrane permeability induced by TNFalpha (show TNF Antibodies) plus cycloheximide, the release of lysosomal cathepsins and reactive oxygen species formation require the caspase-3 (show CASP3 Antibodies)-mediated cleavage of the p75 (show NGFR Antibodies) NDUFS1 subunit of respiratory complex I.

Human NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1) interaction partners

  1. Results found nominal significant associations of 2 SNPs in the NDUFS1 gene and 4 SNPs in the NDUFS2 (show NDUFS2 Antibodies) gene with early onset schizophrenia (EOS (show IKZF4 Antibodies)), but none of these associations survived the Bonferroni correction.

  2. Loss of FOXRED1 (show FOXRED1 Antibodies), coupled with protein, choline and/or folate-deficient diets results in the depletion of glutathione, the dysregulation of nitric oxide metabolism and the peroxynitrite-mediated inactivation of complex I.

  3. NDUFS1 may confer susceptibility to schizophrenia in male subjects, acting as a causative factor for the severity of negative symptoms in schizophrenia.

  4. The presented clinical courses of NDUFV1 (show NDUFV1 Antibodies) and NDUFS1 mutation-based complex I deficiencies are characterized by leukoencephalopathy or early death and expand the already heterogeneous phenotypic spectrum.

  5. Some mutations in NDUFS1 cause a milder phenotype with a more benign course despite the initial decompensation phase. Homozygosity for the c.755A > G missense mutation may correlate with the milder clinical picture in the patient.

  6. homozygous c.1783A>G (p.Thr595Ala) mutation in NDUFS1 in two inbred siblings with isolated complex I deficiency associated to a progressive cavitating leukoencephalopathy

  7. report 3 patients with low residual complex I activity who displayed novel mutations in the NDUFS1 gene. One mutation introduces a premature stop codon, 3 mutations cause a substitution of amino acids and another mutation a deletion of one amino acid.

  8. A patient with Leigh syndrome had a mutation in the NDUFS1 protein of Complex I of the Respiratory Chain. Identifying nuclear mutations will help us understand how molecular defects can lead to complex I deficiency.

  9. mutations in the NDUFS1 and NDUFS4 (show NDUFS4 Antibodies) genes of complex I cause dysfunction in cellular oxidative metabolism

Cow (Bovine) NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1) interaction partners

  1. Data show that during NADH-ubiquinone oxidoreductase (Complex (show NDUFA2 Antibodies) I) catalytic electron transfer from NADH to DBQ, the superoxide generation site was mostly shifted to the SQ.

  2. Data suggest that Q(Nf) plays a role in a "direct" redox-driven proton pump, while Q(Ns) triggers an "indirect" conformation-driven proton pump in NADH-ubiquinone oxidoreductase (complex (show NDUFA2 Antibodies) I).

  3. Bovine heart NADH-ubiquinone oxidoreductase contains one molecule of ubiquinone with ten isoprene units as one of the cofactors

NDUFS1 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with NDUFS1

  • NADH dehydrogenase (ubiquinone) Fe-S protein 1 (Ndufs1) antibody
  • NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) (NDUFS1) antibody
  • 5830412M15Rik antibody
  • 9930026A05Rik antibody
  • CI-75k antibody
  • CI-75Kd antibody
  • PRO1304 antibody

Protein level used designations for NDUFS1

CI-75kD , NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial , complex I-75kD , NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa , complex I 75kDa subunit , complex I, mitochondrial respiratory chain, 75-kD subunit , mitochondrial NADH-ubiquinone oxidoreductase 75 kDa subunit

227197 Mus musculus
301458 Rattus norvegicus
4719 Homo sapiens
478880 Canis lupus familiaris
288380 Bos taurus
100516402 Sus scrofa
459896 Pan troglodytes
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