NDUFS1 antibody (AA 80-290)

Catalog No. ABIN7268819

Product Details anti-NDUFS1 Antibody

Target: NDUFS1 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1))

Binding Specificity: AA 80-290

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFS1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purpose: NDUFS1 Rabbit pAb

Sequence: VEIEKAPKVV AACAMPVMKG WNILTNSEKS KKAREGVMEF LLANHPLDCP ICDQGGECDL QDQSMMFGND RSRFLEGKRA VEDKNIGPLV KTIMTRCIQC TRCIRFASEI AGVDDLGTTG RGNDMQVGTY IEKMFMSELS GNIIDICPVG ALTSKPYAFT ARPWETRKTE SIDVMDAVGS NIVVSTRTGE VMRILPRMHE DINEEWISDK T

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-290 of human NDUFS1 (NP_004997.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NDUFS1

Target: NDUFS1 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 1, 75kDa (NADH-Coenzyme Q Reductase) (NDUFS1))

Alternative Name: NDUFS1 (NDUFS1 Products)

Synonyms: 5830412M15Rik antibody, 9930026A05Rik antibody, CI-75Kd antibody, CI-75k antibody, PRO1304 antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 1 antibody, NADH:ubiquinone oxidoreductase core subunit S1 antibody, Ndufs1 antibody, NDUFS1 antibody

Background: The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene.,NDUFS1,CI-75Kd,CI-75k,PRO1304,Cancer,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Oxidative phosphorylation,Neuroscience,Neurodegenerative Diseases,NDUFS1

Molecular Weight: 67kDa/73kDa/75kDa/79kDa/80kDa

Gene ID: 4719

UniProt: P28331