N-Myc (And STAT) Interactor Proteins (NMI)

NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. Additionally we are shipping NMI Antibodies (52) and NMI Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NMI 17913 Q9WTI7
NMI 9111 Q13287
Rat NMI NMI 311021  
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Top NMI Proteins at antibodies-online.com

Showing 8 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 2 to 3 Days
Human Un-conjugated   5 μg Log in to see 6 Days

NMI Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,

More Proteins for N-Myc (And STAT) Interactor (NMI) Interaction Partners

Mouse (Murine) N-Myc (And STAT) Interactor (NMI) interaction partners

  1. We propose a novel genome-wide mechanism where myosin synergizes with Pol II-associated actin to link the polymerase machinery with permissive chromatin for transcription activation.

  2. Our observations demonstrate specific changes in the expression of myosin IC (show MYO1C Proteins) isoform A that are concurrent with the occurrence of prostate cancer in the TRAMP (show DPT Proteins) mouse prostate cancer model that closely mimics clinical prostate cancer

  3. Ca(2+) binding to calmodulin induces major conformational changes in both IQ motifs and the post-IQ domain and increases flexibility of the myosin-1c tail.

  4. The v-Crk-myosin-1c interaction, which modulates membrane dynamics by regulating Rac1 activity, is crucial for cell adhesion and spreading.

  5. These findings suggest that Nmi is a negative regulator of the virus-triggered induction of type I IFNs that targets IRF7 (show IRF7 Proteins)

  6. Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus.

  7. Myo1c (show MYO1C Proteins) functions as a slow transporter rather than a tension-sensitive anchor.

  8. the novel specific NLS (show ALDH1A2 Proteins) brings to the cell nucleus not only the "nuclear" isoform of myosin I (show MYO1A Proteins) (NM1 (show MYO1C Proteins) protein) but also its "cytoplasmic" isoform (Myo1c (show MYO1C Proteins) protein)

  9. The data suggest that Myosin 1c is involved in the cytoskeleton dynamics and membrane protein anchoring or sorting in B lymphocytes

  10. A hearing loss-associated myo1c mutation (R156W) decreases the myosin duty ratio and force sensitivity

Human N-Myc (And STAT) Interactor (NMI) interaction partners

  1. Data suggest that N-myc (and STAT) interactor (NMI) could improve its downstream target bradykinin B2 receptor (BDKRB2) expression to induce extracellular signal-regulated kinases (ERK) 1 (show MAPK3 Proteins)/2 activation, and thereby further evoke malignant progression of hepatocellular carcinoma (HCC (show FAM126A Proteins)).

  2. N-Myc (show MYCN Proteins)-interacting protein (NMI (show MYO1C Proteins)) negatively regulates epithelial-mesenchymal transition by inhibiting the acetylation of NF-kappaB (show NFKB1 Proteins)/p65 (show GORASP1 Proteins) in histone deacetylase (show HDAC1 Proteins)-dependent manner.

  3. N-myc and STAT interactor sensitizes breast cancer cells to cisplatin treatment through DRAM1 dependent autophagy.

  4. Results show that aberrant miR (show MLXIP Proteins)-29 expression may account for reduced NMI (show MYO1C Proteins) expression in breast tumors and mesenchymal phenotype of cancer cells that promotes invasive growth.

  5. The results showed that SARS (show SARS Proteins) coronavirus protein 6 can promote the ubiquitin-dependent proteosomal degradation of Nmi (show MYO1C Proteins).

  6. overexpression or depletion of NMI (show MYO1C Proteins) revealed its regulation on G1/S progression and cell proliferation (both in vitro and in vivo), and this effect was partially dependent on STAT1 (show STAT1 Proteins), which interacted with and was regulated by NMI (show MYO1C Proteins).

  7. Trim21 (show TRIM21 Proteins) regulates Nmi (show MYO1C Proteins)-IFI35 (show IFI35 Proteins) complex-mediated inhibition of innate antiviral response

  8. Its potential function in transcriptional activation of NMI (show MYO1C Proteins).

  9. identified NMI (show MYO1C Proteins) induction as a novel negative feedback mechanism that decreases IRE1alpha (show ERN1 Proteins)-dependent activation of JNK (show MAPK8 Proteins) and apoptosis in cytokine-exposed beta cells

  10. Thus our work reveals a novel NMI-mediated, transcription-independent ARF induction pathway in response to cellular stresses.

NMI Protein Profile

Protein Summary

NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias.

Gene names and symbols associated with NMI

  • N-myc (and STAT) interactor (nmi)
  • N-myc (and STAT) interactor (NMI)
  • myosin IC (Myo1c)
  • N-myc (and STAT) interactor (Nmi)
  • C80397 protein
  • fj02e01 protein
  • MGC108489 protein
  • mm1beta protein
  • MMIb protein
  • MYO1E protein
  • myr2 protein
  • NMI protein
  • wu:fj02e01 protein

Protein level used designations for NMI

N-myc (and STAT) interactor , N-myc and STAT interactor , MMI-beta , myosin I beta , myosin-Ibeta , myosin-Ic , nuclear myosin I beta , unconventional myosin-Ic , N-myc interactor , N-myc-interactor , N-mcy (and STAT) interactor

335331 Danio rerio
424314 Gallus gallus
470714 Pan troglodytes
476146 Canis lupus familiaris
495484 Xenopus laevis
613094 Xenopus (Silurana) tropicalis
694554 Macaca mulatta
784981 Bos taurus
17913 Mus musculus
9111 Homo sapiens
511280 Bos taurus
311021 Rattus norvegicus
64685 Mus musculus
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